| Grant number: | 14/26905-2 |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |
| Start date: | August 01, 2016 |
| End date: | March 31, 2017 |
| Field of knowledge: | Biological Sciences - Genetics - Molecular Genetics and Genetics of Microorganisms |
| Principal Investigator: | Marcelo Falsarella Carazzolle |
| Grantee: | Sheila Tiemi Nagamatsu |
| Host Institution: | Instituto de Biologia (IB). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil |
Abstract Besides the fact that Brazil is one of the most important world producers of first generation ethanol and it has hundreds plants in its national territory, this process present technological limitations which have encouraged the pursuit for new alternatives, the main one is second generation ethanol that aim use biomass as feedstock. Both first and second generation production present limiting factors to fermentation stage, among them temperature variation, pH alterations, inhibitory molecules and high ethanol concentration. Thus, industrial yeast development to robustness of this factor is an essential step to increase the competitiveness. The genomic study of ethanol industrial yeast have had great importance in gene identification and metabolic pathway associated to robustness, furthermore, this methodology could be useful to select more efficient wild strain to a desirable feature. In this context, the objective of this study is developing a bioinformatics methodology to analyze QTL maps in industrial yeast using ISA (Individual Segregant Analysis) to detect genomic regions linked to the phenotypes of interest. (AU) | |
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