Integration of the extraction/hydrolysis processes in subcritical water and purification for the valuation of grape bagasse in a biorrefinery concept

• Grant number: 21/04096-9
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: December 01, 2021
• End date: December 02, 2026
• Field of knowledge: Agronomical Sciences - Food Science and Technology - Food Engineering
• Principal Investigator: Tânia Forster Carneiro
• Grantee: Luiz Eduardo Nochi de Castro
• Host Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 18/14938-4 - Waste2energy: integration of supercritical technologies and anaerobic digestion through an automated system for the production of biofuel precursors, AP.JP2
• Associated scholarship(s): 24/04678-6 - Sustainable valorization of grape pomace (Vitis vinifera L.): Ionic liquids-assisted recovery and purification of biocompounds through subcritical water processing, BE.EP.DR

Abstract

The demand for technologies to convert biomass and reusing waste has put pressure on the industrial productive sector to increasingly invest in innovations aimed at the generation of new products with high-energy use. In this context, subcritical water technology is recognized as a clean and sustainable process for obtaining bioactive compounds and sugars from by-products generated in the processing of vegetable sources. Therefore, the development of processes that further enhance the technological characteristics of solid waste has been highlighted. The objective of this project is to use an integrated system of extraction followed by hydrolysis in subcritical water and purification of solid residues from the wine processing industry, grape bagasse (seeds and peels), aiming the production of technologies with greater added value. The tests with extraction in subcritical water from the grape bagasse will be evaluated for the production of phenolic and bioactive compounds and evaluation of the antioxidant power. The hydrolysis tests with subcritical water will be evaluated for the production of xylose, arabinose, fructose and inhibitory compounds (furfural and HMF). The bio-adsorbents obtained after the hydrolysis step will be evaluated as an adsorbent material, as well as its adsorptive capacity against different types of bio-adsorbents, biochar and commercial adsorbents. The adsorption tests will be carried out in batch, off-line and in-line column systems, for the purification of inhibition compounds formed during the hydrolysis step. All the processes used in obtaining the co-products will be evaluated technically and economically, the integration of technologies may contribute to the decarbonization of the energy matrix, supporting the transition to a circular economy, based on the reduction, reuse and recovery of energy. (AU)

Scientific publications

(20)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FERREIRA, VANESSA COSME; SGANZERLA, WILLIAM GUSTAVO; BARROSO, TIAGO LINHARES CRUZ TABOSA; CASTRO, LUIZ EDUARDO NOCHI; COLPINI, LEDA MARIA SARAGIOTTO; FORSTER-CARNEIRO, TANIA. Sustainable valorization of pitaya (Hylocereus spp.) peel in a semi-continuous high-pressure hydrothermal process to recover value-added products. Food Research International, v. 173, p. 12-pg., 2023-11-01. (22/02305-2, 21/04096-9, 18/14582-5, 20/16248-5)

BARROSO, TIAGO L. C. T.; CASTRO, LUIZ E. N.; F. BARBERO, GERARDO; PALMA, MIGUEL; CARRERA, CEFERINO; ROSTAGNO, MAURICIO A.; FORSTER-CARNEIRO, TANIA. Optimization of a Microwave-Assisted Extraction Method for the Recovery of the Anthocyanins from Jabuticaba By-Products. AGRONOMY-BASEL, v. 13, n. 2, p. 13-pg., 2023-02-01. (22/02039-0, 18/14938-4, 20/16248-5, 18/14582-5, 21/04096-9)

BARROSO, TIAGO LINHARES CRUZ TABOSA; DA ROSA, RAFAEL GABRIEL; SGANZERLA, WILLIAM GUSTAVO; CASTRO, LUIZ EDUARDO NOCHI; MACIEL-SILVA, FRANCISCO WESHLEY; ROSTAGNO, MAURICIO ARIEL; FORSTER-CARNEIRO, TANIA. Hydrothermal pretreatment based on semi-continuous flow-through sequential reactors for the recovery of bioproducts from jabuticaba (Myrciaria cauliflora) peel. JOURNAL OF SUPERCRITICAL FLUIDS, v. 191, p. 14-pg., 2022-10-19. (18/14582-5, 19/26925-7, 20/16248-5, 21/04096-9)

DA ROSA, RAFAEL GABRIEL; CASTRO, LUIZ EDUARDO NOCHI; BARROSO, TIAGO LINHARES CRUZ TABOSA; FERREIRA, VANESSA COSME; BITTENCOURT, PAULO RODRIGO STIVAL; ROSTAGNO, MAURICIO ARIEL; FORSTER-CARNEIRO, TANIA. Valorizing corn stover waste into valuable bioproducts using subcritical water hydrolysis. BIOFUEL RESEARCH JOURNAL-BRJ, v. 12, n. 1, p. 27-pg., 2025-03-01. (21/04096-9, 18/14582-5, 23/02064-8, 22/02305-2, 18/14938-4)

MANCANO, ROSANA RABELO; MATHEUS, LARISSA RESENDE; CASTRO, LUIZ EDUARDO NOCHI; BARROSO, TIAGO LINHARES CRUZ TABOSA; DA ROSA, RAFAEL GABRIEL; FERREIRA, VANESSA COSME; FORSTER-CARNEIRO, TANIA; COLPINI, LEDA MARIA SARAGIOTTO. Extraction techniques for propolis and its utilization in silver nanoparticle synthesis: a comprehensive review. EUROPEAN FOOD RESEARCH AND TECHNOLOGY, v. N/A, p. 37-pg., 2025-04-05. (24/06628-6, 21/04096-9, 23/02064-8)

SGANZERLA, WILLIAM GUSTAVO; MOREIRA, BARBARA PEZZINI; LACHOS-PEREZ, DANIEL; ZABOT, GIOVANI L.; CASTRO, LUIZ EDUARDO NOCHI; FORSTER-CARNEIRO, TANIA; ROSTAGNO, MAURICIO ARIEL. Techno-economic analysis of amino acids production with subcritical water technology. JOURNAL OF SUPERCRITICAL FLUIDS, v. 222, p. 10-pg., 2025-08-01. (19/26925-7, 18/14582-5, 18/14938-4, 21/04096-9)

BARROSO, TIAGO LINHARES CRUZ TABOSA; CASTRO, LUIZ EDUARDO NOCHI; DA ROSA, RAFAEL GABRIEL; BRACKMANN, RODRIGO; GOLDBECK, ROSANA; FORSTER-CARNEIRO, TANIA. Obtaining value-added products from cashew apple bagasse: A sustainable alternative achieved through a hydrothermal process. Food Research International, v. 208, p. 15-pg., 2025-05-01. (18/14938-4, 22/15221-1, 21/04096-9, 23/02064-8)

CASTRO, LUIZ EDUARDO NOCHI; SGANZERLA, WILLIAM GUSTAVO; SILVA, ALINE PRISCILLA GOMES; JOHN, OLIVER DEAN; BARROSO, TIAGO LINHARES CRUZ TABOSA; ROSTAGNO, MAURICIO A.; FORSTER-CARNEIRO, TANIA. Sustainable extraction methods for the recovery of polyphenolic compounds from grape pomace and its biological properties: a comprehensive review. PHYTOCHEMISTRY REVIEWS, v. N/A, p. 28-pg., 2024-07-05. (19/26925-7, 18/14938-4, 21/04096-9, 23/02064-8, 18/14582-5)

CASTRO, LUIZ EDUARDO NOCHI; SGANZERLA, WILLIAM G.; COSTA, JOSIEL M.; SOUZA, FERNANDO MANZOTTI; ROSTAGNO, MAURICIO A.; FORSTER-CARNEIRO, TANIA. Adsorbents for the purification and recovery of biocompounds: An updated review. BIOFUELS BIOPRODUCTS & BIOREFINING-BIOFPR, v. 18, n. 1, p. 26-pg., 2023-11-27. (19/26925-7, 21/03950-6, 18/14938-4, 21/04096-9, 18/14582-5)

NOCHI CASTRO, LUIZ EDUARDO; SGANZERLA, WILLIAM GUSTAVO; CRUZ TABOSA BARROSOA, TIAGO LINHARES; MACIEL-SILVA, FRANCISCO WESHLEY; SARAGIOTTO COLPINI, LEDA MARIA; STIVAL BITTENCOURT, PAULO RODRIGO; ROSTAGNO, MAURICIO A.; FORSTER-CARNEIRO, TANIA. Improving the semi-continuous flow-through subcritical water hydrolysis of grape pomace (Vitis vinifera L.) by pH and temperature control. JOURNAL OF SUPERCRITICAL FLUIDS, v. 196, p. 14-pg., 2023-02-28. (21/04096-9, 18/14582-5, 18/14938-4, 19/26925-7, 20/16248-5)

BARROSO, TIAGO; SGANZERLA, WILLIAM; ROSA, RAFAEL; CASTRO, LUIZ; MACIEL-SILVA, FRANCISCO; ROSTAGNO, MAURICIO; FORSTER-CARNEIRO, TANIA. Semi-continuous flow-through hydrothermal pretreatment for the recovery of bioproducts from jabuticaba (Myrciaria cauliflora) agro-industrial by-product. Food Research International, v. 158, p. 12-pg., 2022-06-28. (20/16248-5, 18/14582-5, 21/04096-9, 19/26925-7)

TORRES-MAYANGA, PAULO. C. C.; CASTRO, LUIZ E. N.; AZAMBUJA, SUELLEN P. H.; LACHOS-PEREZ, DANIEL; BROWN, AVERY. B. B.; TIMKO, MICHAEL. T. T.; GOLDBECK, ROSANA; FORSTER-CARNEIRO, TANIA; ROSTAGNO, MAURICIO. A. A.. Detoxification of furanic aldehydes of the hemicellulosic hydrothermal hydrolysate of brewers' spent grains by continuous adsorption on a fixed-bed column. BIOFUELS BIOPRODUCTS & BIOREFINING-BIOFPR, v. N/A, p. 14-pg., 2023-02-10. (21/04096-9, 20/10323-5, 18/14938-4, 18/05999-0, 18/14582-5)

DA ROSA, RAFAEL GABRIEL; SGANZERLA, WILLIAM GUSTAVO; BARROSO, TIAGO LINHARES CRUZ TABOSA; CASTRO, LUIZ EDUARDO NOCHI; BERNI, MAURO DONIZETTI; FORSTER-CARNEIRO, TANIA. Sustainable bioprocess combining subcritical water pretreatment followed by anaerobic digestion for the valorization of jabuticaba (Myrciaria cauliflora) agro-industrial by-product in bioenergy and biofertilizer. FUEL, v. 334, p. 15-pg., 2023-02-15. (19/26925-7, 20/16248-5, 21/04096-9)

BARROSO, TIAGO LINHARES CRUZ TABOSA; FERREIRA, VANESSA COSME; CASTRO, LUIZ EDUARDO NOCHI; DA ROSA, RAFAEL GABRIEL; DE SOUZA, LUIZ GUSTAVO ANTONIO; GOLDBECK, ROSANA; FORSTER-CARNEIRO, TANIA. Bioenergy and bioproducts from cashew apple bagasse: a scientometric overview and strategies for sustainable utilization. BIOFUELS BIOPRODUCTS & BIOREFINING-BIOFPR, v. N/A, p. 30-pg., 2024-12-17. (21/04096-9, 24/06628-6, 23/02064-8, 18/14938-4, 22/15221-1)

BARROSO, TIAGO LINHARES CRUZ TABOSA; SGANZERLA, WILLIAM GUSTAVO; CASTRO, LUIZ EDUARDO NOCHI; FREIRIA, NICOLAS LUIS MOREIRA; BARBERO, GERARDO FERNANDEZ; LOVILLO, MIGUEL PALMA; ROSTAGNO, MAURICIO ARIEL; FORSTER-CARNEIRO, TANIA. Removal of 5-hydroxymethylfurfural from brewer's spent grains hydrolysates obtained by subcritical water hydrolysis: An approach using liquid-liquid extraction. JOURNAL OF SUPERCRITICAL FLUIDS, v. 201, p. 9-pg., 2023-06-13. (21/04096-9, 18/14582-5, 18/14938-4, 20/16248-5, 19/26925-7)

FRANCISCO, ANA PAULA; SGANZERLA, WILLIAM GUSTAVO; CASTRO, LUIZ EDUARDO NOCHI; BARROSO, TIAGO LINHARES CRUZ TABOSA; DA SILVA, ALINE PRISCILLA GOMES; DA ROSA, CLEONICE GONCALVES; NUNES, MICHAEL RAMOS; FORSTER-CARNEIRO, TANIA; ROSTAGNO, MAURICIO A.. Pressurized liquid extraction of bioactive compounds from grape peel and application in pH-sensing carboxymethyl cellulose films: A promising material to monitor the freshness of pork and milk. Food Research International, v. 179, p. 12-pg., 2024-01-19. (19/26925-7, 21/04096-9, 20/16248-5, 18/14582-5)

CASTRO, LUIZ EDUARDO NOCHI; BARROSO, TIAGO LINHARES CRUZ TABOSA; FERREIRA, VANESSA COSME; SGANZERLA, WILLIAM GUSTAVO; QUEIROZ, MATHEUS; RIBEIRO, LEOMARA FLORIANO; FORSTER-CARNEIRO, TANIA. Application of functional compounds from agro-industrial residues of Brazilian's tropical fruits extracted by sustainable methods in alginate-chitosan microparticles. BIOACTIVE CARBOHYDRATES AND DIETARY FIBRE, v. 32, p. 12-pg., 2024-08-11. (19/26925-7, 18/14938-4, 21/04096-9, 23/02064-8, 20/16248-5, 22/02305-2)

CASTRO, LUIZ EDUARDO NOCHI; BARROSO, TIAGO LINHARES CRUZ TABOSA; SGANZERLA, WILLIAM GUSTAVO; COSTA, JOSIEL MARTINS; SAIA, FLAVIA TALARICO; COLPINI, LEDA MARIA SARAGIOTTO; FORSTER-CARNEIRO, TANIA. Subcritical water hydrolysis of grape pomace as a sustainable pretreatment for anaerobic digestion in a biorefinery concept. FUEL, v. 363, p. 15-pg., 2024-01-19. (19/26925-7, 21/03950-6, 18/14938-4, 21/04096-9, 20/16248-5)

BARROSO, TIAGO LINHARES CRUZ TABOSA; CASTRO, LUIZ EDUARDO NOCHI; DE SOUZA MESQUISTA, LEONARDO M.; BARBERO, GERARDO FERNANDEZ; CARRERA, CEFERINO; ROSTAGNO, MAURICIO ARIEL; FORSTER-CARNEIRO, TANIA. Simple procedure for the simultaneous extraction and purification of anthocyanins using a jabuticaba byproduct biosorbent. Journal of Food Composition and Analysis, v. 130, p. 10-pg., 2024-03-29. (18/14938-4, 22/02039-0, 21/04096-9, 20/16248-5, 18/14582-5)

BARROSO, TIAGO LINHARES CRUZ TABOSA; CASTRO, LUIZ EDUARDO NOCHI; LIMA, JOSE ROMUALDO DE SOUSA; COLPINI, LEDA MARIA SARAGIOTTO; ROSTAGNO, MAURICIO ARIEL; FORSTER-CARNEIRO, TANIA. Synthesis and Optimization of biosorbent using jabuticaba peel (Myrciaria cauliflora) for anthocyanin recovery through adsorption. ADSORPTION-JOURNAL OF THE INTERNATIONAL ADSORPTION SOCIETY, v. 30, n. 6, p. 21-pg., 2024-05-18. (20/16248-5, 18/14582-5, 21/04096-9)