CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Pharmacy-Biochemistry from the University of São Paulo (2002) and PhD in Food Sciences (USP - 2007) with a period at the University of Nottingham (RU). He has a Post-Doctorate at USP (2008-2011) with an internship at the University of Nottingham. He is currently an Associate Professor at the Department of Food and Experimental Nutrition at the Faculty of Pharmaceutical Sciences at USP. He is interested in the area of Chemistry, Biochemistry and Molecular Biology of Foods of plant origin, specifically in understanding the molecular basis of the ripening of edible fruits and the relationship between consumption of foods of plant origin X possible benefits to human health. He is Principal Investigator at FoRC (Food Research Center), one of the Innovation, Research and Dissemination Centers (CEPIDs) supported by FAPESP. He is a member of the Scientific Board (Board of Directors) and of the Scientific and Administrative Council (Board of Trustees) of the International Life Sciences Institute (ILSI) Brazil. (Source: Lattes Curriculum)
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Anthocyanins are polyphenolic compounds with potential beneficial properties for human health. However, they are bioactive compounds with high molecular instability due to environmental factors and those inherent in human intestinal digestion. In the gastrointestinal tract, anthocyanins undergo an intense process of structural biotransformation, reducing their functionalities, limiting th…
The consumption of dietary fiber from fruits benefits human health by reducing the incidence of chronic noncommunicable diseases (NCDs). The soluble fibers of the fruits are derived from pectins that can be chemically modified and can then exert immunomodulatory action in the colon. These bioactive modified pectins are formed by galacturonans and low molecular weight galactans that are ex…
The Food Research Center (FoRC) is an initiative of scientists from University of São Paulo for creation of the first research center focused on food and nutrition in Brazil. It is based on the concept that food and nutrition studies present a multidisciplinary character, and professionals with different backgrounds can study different aspects of the same subject. The main goal is to addr…
The consumption of dietary fibers (DF), especially the non-digestible polysaccharides, has been related to the decrease in the incidence of colon cancer. Fruits, such as papayas, are foods rich in pectins, which constitute a large amount of the DF fraction of the fruit. Papaya has a very fast ripening, with consequent pulp softening and modification of the DF structures. The DF from ripe …
(Only some records are available in English at this moment)
Dysregulation of the gut microbiota is associated with the development of neurological, metabolic, and inflammatory diseases and is influenced by dietary habits, such as low intake of soluble fibers. Pectins, a type of water-soluble fiber found in fruits, promote the growth of beneficial gut bacteria by being degraded by colonic microbiota. Their modulatory effects depend on structural ch…
Anthocyanins are bioactive compounds that stand out for their ability to alter the intestinal microbiota, leading to beneficial systemic effects. Despite this, the therapeutic use of anthocyanins is quite limited due to their high molecular instability, intense degradation throughout the gastrointestinal tract, and limited reach to the distal portions of the intestine, especially of the i…
Anthocyanins are polyphenolic compounds with potential beneficial properties for human health. However, they are bioactive compounds with high molecular instability due to environmental factors and those inherent in human intestinal digestion. In the gastrointestinal tract, anthocyanins undergo an intense process of structural biotransformation, reducing their functionalities, limiting th…
The lifestyle of the current man with low intake of fruits made several chronic non-communicable diseases (NCD), such as colon cancer, more common. Fruits are excellent sources of dietary fiber, and pectins have received attention due to some beneficial effects besides colonic fermentation. The best studied pectins are modified citrus pectin (PMC) and ripe papayas pectin. The first is the…
The dysregulation of the intestinal microbial community plays an important role in the development of neurological, metabolic, and inflammatory diseases. Intestinal dysbiosis is closely linked to specific eating habits, such as low consumption of soluble fiber. Intake of pectin, a soluble fiber found in fruit, can significantly influence gut health. Its breakdown in the body, which mainly…
Wheat bran is the layer where most of the dietary fiber and minerals in the grain are found. However, it is discarded in the milling process to obtain wheat flour. Despite the richness of polysaccharides in bran, extraction is often uninteresting and costly for the food industry. Colon Cancer is one of the most common cancers worldwide and both diet and lifestyle have been shown to play a…
(Only some records are available in English at this moment)
Some plant-derived polysaccharides present immunomodulatory potential. A proinflammatory environment can aggravate colorectal cancer pathogenesis and progression. Pectins have been studied in this regard as protector molecules. One of the most promising results in this area is the interaction between different pectic epitopes and varied Toll-like receptors. The capacity of restoring intes…
Colorectal cancer is a major health problem worldwide. The intake of dietary fiber has been associated to a decrease of colon cancer, especially the intake of soluble fibers, such as pectins. Papaya fibers have been linked to several anti-cancer and anti-inflammatory activities in 2D models, including the induction of apoptosis, cell cycle arrest, and regulation of expression of toll-like…
| 3 / 3 | Ongoing grants |
| 6 / 6 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 19 / 17 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 33 / 31 | All research grants and scholarships |
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