| Full text | |
| Author(s): |
Reno, Caroline de Oliveira
[1]
;
Pereta, Nicholas C.
[1]
;
Bertran, Celso A.
[2]
;
Motisuke, Mariana
[1]
;
de Sousa, Eliandra
[1]
Total Authors: 5
|
| Affiliation: | [1] Fed Univ Sao Paulo UNIFESP, Inst Sci & Technol, Bioceram Lab, BR-12231280 Sao Paulo - Brazil
[2] Univ Campinas UNICAMP, Inst Chem, Dept Phys Chem, Campinas, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE; v. 25, n. 10, p. 2297-2303, OCT 2014. |
| Web of Science Citations: | 8 |
| Abstract | |
An interest path to fabricate supports for tissue engineering is to foam calcium phosphate cement's pastes leading to an increase on material's total porosity and interconnectivity which facilitates cells' adhesion, proliferation and differentiation. The aim of this work is to develop scaffolds of brushite cement and to evaluate its in vitro degradation rate. Macroporosity was obtained by foaming the liquid phase with different non-ionic surfactants (Tween 80 and Lutensol ON-110). The foam stability was achieved by adding chitosan. The scaffolds were immersed in Ringers(A (R)) solution during 7, 14, 21 and 28 days and samples' microstructure, weight loss, mechanical resistance and apparent porosity were evaluated. Both scaffolds presented interconnected macropores with sizes ranging from 100 to 360 A mu m and total porosities higher than 60 %. These properties could facilitate cell infiltration, bone growth and vascularization. The scaffolds obtained in this work should be considered as promising materials for application in bone tissue engineering. (AU) | |
| FAPESP's process: | 10/00863-0 - Processing and characterization of B-TCP/Al2O3 nanostructured scaffolds for biomedical applications |
| Grantee: | Eliandra de Sousa Trichês |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 11/09240-9 - Calcium phosphate cement otimization for application in orthopedics and tissue engineering |
| Grantee: | Mariana Motisuke |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 12/21198-0 - Bioactive and reabsorbable calcium phosphate microspheres for drug delivery |
| Grantee: | Caroline de Oliveira Renó |
| Support Opportunities: | Scholarships in Brazil - Master |