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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Dispelling the myth that habitual caffeine consumption influences the performance response to acute caffeine supplementation

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Goncalves, Livia de Souza ; Painelli, Vitor de Salles ; Yamaguchi, Guilherme ; de Oliveira, Luana Farias ; Saunders, Bryan ; da Silva, Rafael Pires ; Maciel, Erika ; Artioli, Guilherme Giannini ; Roschel, Hamilton ; Gualano, Bruno
Total Authors: 10
Document type: Journal article
Source: Journal of Applied Physiology; v. 123, n. 1, p. 213-220, JUL 2017.
Web of Science Citations: 44

This study investigates the influence of habitual caffeine intake on aerobic exercise-performance responses to acute caffeine supplementation. A double-blind, crossover, counterbalanced study was performed. Forty male endurancetrained cyclists were allocated into tertiles, according to their daily caffeine intake: low (58 +/- 29 mg/d), moderate (143 +/- 25 mg/d), and high (351 +/- 139 mg/d) consumers. Participants completed three trials in which they performed simulated cycling time trials (TTs) in the fastest time possible following ingestion of the following: caffeine (CAF: 6 mg/kg body mass), placebo (PLA), and no supplement (CON). A mixed-model analysis revealed that TT performance was significantly improved in CAF compared with PLA and CON (29.92 +/- 2.18 vs. 30.81 +/- 2.67 and 31.14 +/- 2.71 min, respectively; P = 0.0002). Analysis of covariance revealed no influence of habitual caffeine intake as a covariate on exercise performance (P = 0.47). TT performance was not significantly different among tertiles (P = 0.75). No correlation was observed between habitual caffeine intake and absolute changes (CAF = CON) in TT performance with caffeine (P = 0.524). Individual analysis showed that eight, seven, and five individuals improved above the variation of the test in CAF in the low, moderate, and high tertiles, respectively. A Fisher's exact test did not show any significant differences in the number of individuals who improved in CAF among the tertiles (P > 0.05). Blood lactate and ratings of perceived exertion were not different between trials and tertiles (P > 0.05). Performance effects of acute caffeine supplementation during an similar to 30-min cycling TT performance were not influenced by the level of habitual caffeine consumption. (AU)

FAPESP's process: 11/19513-2 - Effects of Chronic Beta-Alanine Supplementation with and without Acute Sodium Bicarbonate Ingestion on Peak Muscle Carnosine Concentration, Washout and High-Intensity Exercise Performance
Grantee:Bryan Saunders
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 13/04806-0 - Effects of 12 weeks of high-intensity intermittent training on intramuscular carnosine concentrations
Grantee:Vitor de Salles Painelli
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 13/14746-4 - Carnosine metabolism in skeletal muscle: a multi-approach study
Grantee:Bruno Gualano
Support type: Research Projects - Thematic Grants
Grantee:Rafael Pires da Silva
Support type: Scholarships in Brazil - Doctorate