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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Mechanism of Action of TiF4 on Dental Enamel Surface: SEM/EDX, KOH-Soluble F, and X-Ray Diffraction Analysis

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Author(s):
Comar, Livia P. [1, 2] ; Souza, Beatriz M. [1] ; Al-Ahj, Luana P. [1] ; Martins, Jessica [1] ; Grizzo, Larissa T. [1] ; Piasentim, Isabelle S. [1] ; Rios, Daniela [3] ; Rabelo Buzalaf, Marilia Afonso [1] ; Magalhaes, Ana Carolina [1]
Total Authors: 9
Affiliation:
[1] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Al Octavio Pinheiro Brisolla 9-75, BR-17012901 Bauru, SP - Brazil
[2] Univ Marilia UNIMAR, Dept Dent, Marilia - Brazil
[3] Univ Sao Paulo, Bauru Sch Dent, Dept Orthodont Pediat Dent & Publ Hlth, Bauru - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Caries Research; v. 51, n. 6, p. 554-567, 2017.
Web of Science Citations: 5
Abstract

This in vitro study aimed to evaluate the action of TiF4 on sound and carious bovine and human enamel. Sound (S) and pre-demineralised (DE) bovine and human (primary and permanent) enamel samples were treated with TiF4 (pH 1.0) or NaF varnishes (pH 5.0), containing 0.95, 1.95, or 2.45% F for 12 h. The enamel surfaces were analysed using SEM-EDX (scanning electron microscopy/ energy-dispersive X-ray spectroscopy) (n = 10, 5 S and 5 DE) and KOH-soluble fluoride was quantified (n = 20, 10 S and 10 DE). Hydroxyapatite powder produced by precipitation method was treated with the corresponding fluoride solutions for 1 min (n = 2). The formed compounds were detected using X-ray diffraction (XRD). All TiF4 varnishes produced a coating layer rich in Ti and F on all types of enamel surface, with micro-cracks in its extension. TiF4 (1.95 and 2.45% F) provided higher fluoride deposition than NaF, especially for bovine enamel (p < 0.0001). It also induced a higher fluoride deposition on DE samples compared to S samples (p < 0.0001), except for primary enamel. The Ti content was higher for bovine and human primary enamel than human permanent enamel, with some differences between S and DE. The XRD analysis showed that TiF4 induced the formation of new compounds such as CaF2, TiO2, and Ti(HPO4)(2) center dot H2O. In conclusion, TiF4 (>0.95%F) interacts better, when compared to NaF, with bovine and human primary enamel than with human permanent enamel. TiF4 provoked higher F deposition compared to NaF. Carious enamel showed higher F uptake than sound enamel by TiF4 application, while Ti uptake was dependent on the enamel condition and origin. (c) 2017 S. Karger AG, Basel (AU)

FAPESP's process: 10/07001-4 - Evaluation of the effect of an experimental paste with calcium phosphate nanoparticles on enamel demineralization in vitro
Grantee:Beatriz Martines de Souza
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 11/11263-7 - Evaluation of TiF4 interaction with hydroxyapatite and enamel and the effect on the de-remineralization of artificial caries enamel lesion in situ
Grantee:Livia Picchi Comar
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 12/00662-0 - Evaluation of the titanium tetrafluoride (TiF4) interaction with sound and demineralized human enamel in vitro
Grantee:Jéssica Martins
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 13/20372-0 - Effect of titanium tetrafluoride varnish on fibroblasts (NIH3T3): viability assay, morphological analysis and cell signals for apoptotic pathways
Grantee:Ana Carolina Magalhães
Support type: Regular Research Grants
FAPESP's process: 12/20698-0 - Effect of TiF4 on hydroxiapatite and enamel subjected to cariogenic and erosive processes: in vitro and in situ studies
Grantee:Ana Carolina Magalhães
Support type: Regular Research Grants