Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Evidence of natural Zika virus infection in neotropical non-human primates in Brazil

Full text
Author(s):
Show less -
Terzian, Ana Carolina B. [1] ; Zini, Nathalia [1] ; Sacchetto, Livia [2] ; Rocha, Rebeca Froes [3] ; Pereira Parra, Maisa Carla [1] ; Del Sarto, Juliana Lemos [3] ; Fialho Dias, Ana Carolina [3] ; Coutinho, Felipe [3] ; Rayra, Jessica [3] ; da Silva, Rafael Alves [1] ; Costa, Vivian Vasconcelos [3] ; Couto De Azevedo Fernandes, Natalia Coelho [4] ; Ressio, Rodrigo [4] ; Diaz-Delgado, Josue [4] ; Guerra, Juliana [4] ; Cunha, Mariana S. [4] ; Catao-Dias, Jose Luiz [5] ; Bittar, Cintia [6] ; Negri Reis, Andreia Francesli [7] ; Penha dos Santos, Izalco Nuremberg [7] ; Marascalchi Ferreira, Andreia Cristina [7] ; Arao Antonio Cruz, Lilian Elisa [7] ; Rahal, Paula [6] ; Ullmann, Leila [8] ; Malossi, Camila [8] ; de Araujo, Jr., Joao Pessoa [8] ; Widen, Steven [9] ; de Rezende, Izabela Mauricio [2] ; Mello, Erica [10] ; Pacca, Carolina Colombelli [11] ; Kroon, Erna Geessien [2] ; Trindade, Giliane [2] ; Drumond, Betania [2] ; Chiaravalloti-Neto, Francisco [12] ; Vasilakis, Nikos [13, 14] ; Teixeira, Mauro M. [3] ; Nogueira, Mauricio Lacerda [1]
Total Authors: 37
Affiliation:
Show less -
[1] Sao Jose do Rio Preto Sch Med FAMERP, Ave Brigadeiro Faria Lima 5416, BR-15090000 Sao Jose Do Rio Preto, SP - Brazil
[2] Univ Fed Minas Gerais, Lab Virus, Ave Antonio Carlos 6627, BR-31270901 Belo Horizonte, MG - Brazil
[3] Univ Fed Minas Gerais, Ctr Drug Res & Dev, Inst Ciencias Biol, Ave Antonio Carlos 6627, BR-31270901 Belo Horizonte, MG - Brazil
[4] IAL, Ave Dr Arnaldo, 351-7 Andar, Sala 706, BR-01246000 Sao Paulo, SP - Brazil
[5] Univ Sao Paulo, FMVZ, LAPOCM, Lab Wildlife Comparat Pathol, Dept Pathol, Sch Vet, Ave Orlando Marques de Paiva 87, BR-05508270 Sao Paulo, SP - Brazil
[6] Sao Paulo State Univ, Inst Biosci Letters & Exact Sci, Dept Biol, Sao Jose Rio Preto IBILCE, UNESP, Rua Cristovao Colombo 2265, BR-15054000 Sao Jose Do Rio Preto, SP - Brazil
[7] Epidemiol Surveillance Dept Sao Jose Do Rio Preto, Ave Romeu Strazzi 199, BR-15084010 Sao Jose Do Rio Preto, SP - Brazil
[8] Sao Paulo State Univ Unesp, Inst Biotechnol, Alameda Tecomarias S-N, BR-18607440 Botucatu, SP - Brazil
[9] Univ Texas Med Branch, Dept Biochem & Mol Biol, 301 Univ Blvd, Galveston, TX 77555 - USA
[10] Belo Horizonte Council, Ctr Controle Zoonoses, Rua Edna Quintel 173, BR-31270705 Belo Horizonte, MG - Brazil
[11] Faceres Med Sch, Ave Anisio Haddad 6751, BR-15090305 Sao Jose Do Rio Preto, SP - Brazil
[12] Univ Sao Paulo, Sch Publ Hlth, Dept Epidemiol, Ave Dr Arnaldo 715, BR-01246904 Sao Paulo, SP - Brazil
[13] Univ Texas Med Branch, Dept Pathol, 301 Univ Blvd, Galveston, TX 77555 - USA
[14] Univ Texas Med Branch, Ctr Biodef & Emerging Infect Dis, Ctr Trop Dis, Inst Human Infect & Immun, 301 Univ Blvd, Galveston, TX 77555 - USA
Total Affiliations: 14
Document type: Journal article
Source: SCIENTIFIC REPORTS; v. 8, OCT 30 2018.
Web of Science Citations: 14
Abstract

In Africa, Old World Primates are involved in the maintenance of sylvatic circulation of ZIKV. However, in Brazil, the hosts for the sylvatic cycle remain unknown. We hypothesized that free-living NHPs might play a role in urban/periurban ZIKV dynamics, thus we undertook an NH P ZIKV investigation in two cities in Brazil. We identified ZIKV-positive NHPs and sequences obtained were phylogenetically related to the American lineage of ZIKV. Additionally, we inoculated four C. penicillata with ZIKV and our results demonstrated that marmosets had a sustained viremia. The natural and experimental infection of NHPs with ZIKV, support the hypothesis that NHPs may be a vertebrate host in the maintainance of ZIKV transmission/circulation in urban tropical settings. Further studies are needed to understand the role they may play in maintaining the urban cycle of the ZIKV and how they may be a conduit in establishing an enzootic transmission cycle in tropical Latin America. (AU)

FAPESP's process: 14/23159-8 - VIRAL GENOME RESEARCH IN TROPICAL BATS THROUGH METAGENOMICS
Grantee:Leila Sabrina Ullmann
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 13/21719-3 - Epidemiological study of dengue (serotypes1-4) in a cohort of São José do Rio Preto, São Paulo, Brazil, during 2014-2018
Grantee:Maurício Lacerda Nogueira
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 16/15021-1 - Clinical-epidemiological study of a cohort of Zika infected pregnant women in São José do Rio Preto, SP
Grantee:Maurício Lacerda Nogueira
Support Opportunities: Research Grants - Research in Public Policies for the National Health Care System (PP-SUS)
FAPESP's process: 15/12295-0 - Diagnostic of Brazilian and emergent arboviruses in patients and mosquitoes from two distinct regions in Brazil
Grantee:Ana Carolina Bernardes Terzian
Support Opportunities: Scholarships in Brazil - Post-Doctoral