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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A first step towards building spectral libraries as complementary tools for snake venom proteome/peptidome studies

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Author(s):
Zelanis, Andre [1] ; Silva, Debora A. [2] ; Kitano, Eduardo S. [2, 3] ; Liberato, Tarcisio [1] ; Fukushima, Isabella [1] ; Serrano, Solange M. T. [2] ; Tashima, Alexandre K. [2, 4]
Total Authors: 7
Affiliation:
[1] Univ Fed Sao Paulo ICT UNIFESP, Dept Sci & Technol, Funct Prote Lab, Sao Jose Dos Campos, SP - Brazil
[2] Inst Butantan, Ctr Toxins Immune Response & Cell Signaling CeTIC, Lab Especial Toxinol Aplicada, Sao Paulo - Brazil
[3] Univ Sao Paulo HCFMUSP, Fac Med, Hosp Clin, Lab Imunol, Sao Paulo - Brazil
[4] Univ Fed Sao Paulo EPM UNIFESP, Escola Paulista Med, Dept Bioquim, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Comparative Biochemistry and Physiology D-Genomics & Proteomics; v. 31, SEP 2019.
Web of Science Citations: 0
Abstract

Snake venoms are complex mixtures of a large number of distinct proteins and peptides with biological activity. Peptide spectral libraries are compilations of previously identified MS/MS spectra obtained from proteomics experiments. Here we present the generation and use of a Venom Peptidome and a Venom Proteome spectral library for the analysis of venom proteomes and peptidomes from distinct snake species. (AU)

FAPESP's process: 13/14651-3 - Experimental approaches in proteomics and glycomics applied to the characterization of Bothrops alcatraz
Grantee:Débora Andrade Silva
Support type: Scholarships in Brazil - Master
FAPESP's process: 14/06579-3 - System-wide analysis of N-terminal processing and protein diversity in the secretome of tumor cells
Grantee:André Zelanis Palitot Pereira
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 17/20106-9 - Peptidomics of Brazilian snake and spider venoms
Grantee:Alexandre Keiji Tashima
Support type: Regular Research Grants
FAPESP's process: 13/07467-1 - CeTICS - Center of Toxins, Immune-Response and Cell Signaling
Grantee:Hugo Aguirre Armelin
Support type: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 17/07897-7 - Proteolytic processing analysis in the secretome of melanoma tumor cells
Grantee:Isabella Fukushima
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 13/13548-4 - Proteomic/Glycoproteomic characterization of the venoms of the Bothrops jararaca complex with emphasis on the N-terminome and N-glycome of toxins
Grantee:Solange Maria de Toledo Serrano
Support type: Regular Research Grants