| Full text | |
| Author(s): |
Fava, Elson Luiz
[1]
;
do Prado, Thiago Martimiano
[1]
;
Garcia-Filho, Amauri
[1]
;
Silva, Tiago Almeida
[1, 2]
;
Cincotto, Fernando Henrique
[3, 1]
;
de Moraes, Fernando Cruz
[1]
;
Faria, Ronaldo Censi
[1]
;
Fatibello-Filho, Orlando
[1]
Total Authors: 8
|
| Affiliation: | [1] Univ Fed Sao Carlos, Dept Chem, POB 676, BR-13560970 Sao Carlos, SP - Brazil
[2] Fed Ctr Technol Educ Minas Gerais, Dept Met & Chem, BR-35180008 Timoteo, MG - Brazil
[3] Univ Fed Rio de Janeiro, Inst Chem, Rio De Janeiro, RJ - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | Talanta; v. 207, JAN 15 2020. |
| Web of Science Citations: | 0 |
| Abstract | |
A low-cost and disposable microcell was constructed with a screen-printed electrode for the non-enzymatic electrochemical determination of creatinine. The working electrode was modified with carbon black and maintained in contact with paper-adsorbed iron (III) ions. A small sample volume of 3 mu L was required for the device operation. Then, iron (III) ions were complexed in the presence of creatinine in a chemical step, followed by an electrochemical reduction of non-complexed metallic ions in excess. Cyclic voltammetry and differential-pulse voltammetry experiments were employed for the electrochemical characterizations and analytical performance evaluation of the microcell. The working electrode modification with carbon black provided a significant increase of analytical signal. The sensor presented a linear response for creatinine concentrations ranging from 0.10 to 6.5 mmol L-1, with a limit of detection of 0.043 mmol L-1. Experiments for creatinine determination in real samples were successful performed through of standard recovery in urine. (AU) | |
| FAPESP's process: | 17/24053-7 - Development of simple electrochemical methods for the detection of biomarkers for the diagnosis of diseases |
| Grantee: | Ronaldo Censi Faria |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 16/10012-4 - Development of a disposable biosensors array with a microfluidic device for multiplex determination of species of biological interest in different matrices |
| Grantee: | Elson Luiz Fava |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 17/10118-0 - Study and application of electrochemical technology for the analysis and degradation of endocrine interferents: materials, sensors, processes and scientific dissemination |
| Grantee: | Marcos Roberto de Vasconcelos Lanza |
| Support Opportunities: | Research Projects - Thematic Grants |