| Full text | |
| Author(s): |
Azambuja, Sueellen P. H.
[1]
;
Teixeira, Gleidson S.
[1]
;
Andrietta, Maria G. S.
[2]
;
Torres-Mayanga, Paulo C.
[3]
;
Forster-Carneiro, Tania
[3]
;
Rosa, Carlos A.
[4]
;
Goldbeck, Rosana
[1]
Total Authors: 7
|
| Affiliation: | [1] Univ Estadual Campinas, Sch Food Engn, Dept Food Engn, Lab Bioproc & Metab Engn, BR-13083862 Campinas, SP - Brazil
[2] Univ Estadual Campinas, Chem Biol & Agr Pluridisciplinary Res Ctr CPQBA, BR-13148218 Campinas, SP - Brazil
[3] Univ Estadual Campinas, Sch Food Engn, Dept Food Engn, Lab Bioengn & Water & Waste Treatment, BR-13083862 Campinas, SP - Brazil
[4] Univ Fed Minas Gerais, Dept Microbiol, BR-31270901 Belo Horizonte, MG - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | FEMS Microbiology Letters; v. 366, n. 13 JUL 2019. |
| Web of Science Citations: | 0 |
| Abstract | |
Butanol has advantages over ethanol as a biofuel. Although butanol is naturally produced by some Clostridium species, clostridial fermentation has inherent characteristics that prevent its industrial application. Butanol-producing Saccharomyces cerevisiae strains may be a solution to this problem. The aim of this study was to evaluate the ability of wild-type and industrial Brazilian strains of S. cerevisiae to produce n-butanol using glycine as co-substrate and evaluate the relationship between the production of this alcohol and other metabolites in fermented broth. Of the 48 strains analyzed, 25 were able to produce n-butanol in a glycine-containing medium. Strains exhibited different profiles of n-butanol, isobutanol, ethanol, glycerol and acetic acid production. Some wild-type strains showed substantial n-butanol production capability, for instance UFMG-CM-Y267, which produced about 12.7mg/L of butanol. Although this concentration is low, it demonstrates that wild-type S. cerevisiae can synthesize butanol, suggesting that selection and genetic modification of this microorganism could yield promising results. The findings presented here may prove useful for future studies aimed at optimizing S. cerevisiae strains for butanol production. (AU) | |
| FAPESP's process: | 18/05999-0 - Waste2energy: integration of the supercritical and anaerobic digestion technologies for the management of water and food waste |
| Grantee: | Tânia Forster Carneiro |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 15/50612-8 - An integrated approach to explore a novel paradigm for biofuel production from lignocellulosic feedstocks |
| Grantee: | Telma Teixeira Franco |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 15/20630-4 - Biorefinery development integrated to a bioethanol sugar cane plant with zero CO2 emission: routes to convert renewable resources to bio-products and bio-electricity |
| Grantee: | Rubens Maciel Filho |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 16/04602-3 - Development of Saccharomyces cerevisiae strains through heterologous expression of cellulases and evolutionary engineering aiming for simultaneous saccharification and fermentation of lignocellulosic biomass |
| Grantee: | Rosana Goldbeck Coelho |
| Support Opportunities: | Program for Research on Bioenergy (BIOEN) - Regular Program Grants |
| FAPESP's process: | 16/02506-7 - Development of high-throughput approaches for the study of quantitative traits loci related to robustness of industrial yeasts (Saccharomyces cerevisiae) |
| Grantee: | Gleidson Silva Teixeira |
| Support Opportunities: | Program for Research on Bioenergy (BIOEN) - Regular Program Grants |