| Full text | |
| Author(s): |
Aline Sayuri Lima Iida
[1]
;
Karina Novais Luz
[2]
;
Taís Téo Barros-Alexandrino
;
Carmen Sílvia Fávaro-Trindade
[4]
;
Samantha Cristina de Pinho
[5]
;
Odílio Benedito Garrido Assis
[6]
;
Milena Martelli-Tosi
[7]
Total Authors: 7
|
| Affiliation: | [1] Universidade de São Paulo. Faculdade de Zootecnia e Engenharia de Alimentos. Departamento de Engenharia de Alimentos - Brasil
[2] Universidade de São Paulo. Faculdade de Zootecnia e Engenharia de Alimentos. Departamento de Engenharia de Alimentos - Brasil
[4] Universidade de São Paulo. Faculdade de Zootecnia e Engenharia de Alimentos. Departamento de Engenharia de Alimentos - Brasil
[5] Universidade de São Paulo. Faculdade de Zootecnia e Engenharia de Alimentos. Departamento de Engenharia de Alimentos - Brasil
[6] Embrapa Instrumentação. Laboratório Nacional de Nanotecnologia para o Agronegócio - Brasil
[7] Universidade de São Paulo. Faculdade de Zootecnia e Engenharia de Alimentos. Departamento de Engenharia de Alimentos - Brasil
Total Affiliations: 7
|
| Document type: | Journal article |
| Source: | POLIMEROS-CIENCIA E TECNOLOGIA; v. 29, n. 4 2020-04-06. |
| Abstract | |
Abstract Tripolyphosphate (TPP)-chitosomes were produced aiming at the encapsulation and conservation of vitamin D3. This hybrid system is made of liposomes, vesicles consisting of phospholipid bilayers, surrounded by chitosan wall ionic-crosslinked with TPP. Chitosan concentrations (2 and 4 mg mL-1) were tested and the vitamin stability in aqueous dispersions monitored for 49 days. The results confim that D3 remained stable throughout the analyzed period (49 days), whereas the non-encapsulated vitamin totally degrades after the second week of storage. The particle diameters ranged from 0.1 to 5 μm with good colloidal stability (+22 to +48 mV), and encapsulation efficiency of 97%. Thermal stability was also improved when using the TPP-chitosomes. The protection performed was attributed to the stable interactions conferred by the phospholipids crosslinking with the chitosan amino groups and a formation of a net of hydrogen bonds established amongst the hydroxyl groups of the interacting compounds as revealed by infrared spectroscopy. (AU) | |
| FAPESP's process: | 16/18788-1 - Raman microspectroscopy and chemometrics for the characterization of polymer-based microcarrier systems of active/photoactive compounds |
| Grantee: | Milena Martelli Tosi |
| Support Opportunities: | Regular Research Grants |