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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Catalytic Friedel-Crafts Alkylation of Electron Rich Aromatic Derivatives with alpha-Aryl Diazoacetates Mediated by Bronsted Acids

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Author(s):
Gallo, Rafael D. C. [1] ; Momo, Patricia B. [1] ; Day, David P. [1] ; Burtoloso, Antonio C. B. [1]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: ORGANIC LETTERS; v. 22, n. 6, p. 2339-2343, MAR 20 2020.
Web of Science Citations: 0
Abstract

The catalytic protonation of aryl diazoacetates by strong Bronsted acids, followed by a Friedel-Crafts alkylation reaction with electron rich aromatic compounds, is reported. The reaction provided in a direct fashion 24 geminal diarylacetates in yields of <= 92%. (AU)

FAPESP's process: 09/54040-8 - Acquisition of a high-resolution Orbitrap mass spectrometer for the discovery and structural analysis of biologically active compounds: applications in proteomics, biomarkers, synthesis, isolation, and characterization of natural products, studies of redox systems in food and enzymatic synthesis
Grantee:Emanuel Carrilho
Support Opportunities: Multi-user Equipment Program
FAPESP's process: 13/50228-8 - Biodiversity components, and their metabolic characters, of Brazilian Islands: an integrated approach
Grantee:Roberto Gomes de Souza Berlinck
Support Opportunities: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 15/22003-7 - Asymmetric Aza-Michael Addition from unsaturated diazoketones.
Grantee:Patrícia Betoni Momo
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 19/05002-8 - Exploration of Enantioselective Transformations of Diazoketones and Sulfoxonium Ylides
Grantee:David Philip Day
Support Opportunities: Scholarships in Brazil - Post-Doctoral