The Mediating Role of Lean Soft Tissue in the Relationship between Somatic Maturation and Bone Density in Adolescent Practitioners and Non-Practitioners of Sports

Author(s)

Agostinete, Ricardo R. ^[1] ; Werneck, Andre O. ^[2] ; Maillane-Vanegas, Santiago ^[1] ; Gracia-Marco, Luis ^{[3, 4]} ; Ubago-Guisado, Esther ^{[3, 4, 5]} ; Constable, Annie M. ^{[6, 7]} ; Fernandes, Romulo A. ^[1] ; Vlachopoulos, Dimitris ^[6]

Affiliation

^[1] Sao Paulo State Univ UNESP, Lab InVest Exercise LIVE, Dept Phys Educ, BR-19060900 Presidente Prudente - Brazil

^[2] Univ Sao Paulo, Ctr Epidemiol Res Nutr & Hlth, Sch Publ Hlth, Dept Nutr, BR-01246904 Sao Paulo - Brazil

^[3] Univ Granada, PROFITH PROmoting FITness & Hlth Phys Act, Res Grp, Fac Sport Sci, Sport & Hlth Univ Res Inst iMUDS, Dept Phys Educ &, Granada 18071 - Spain

^[4] Inst Invest Biosanitaria Ibs GRANADA, Granada 18012 - Spain

^[5] Escuela Andaluza Salud Publ EASP, Granada 18011 - Spain

^[6] Univ Exeter, Childrens Hlth & Exercise Res Ctr, Sport & Hlth Sci, Exeter EX1 1TX, Devon - England

^[7] Univ Eastern Finland, Inst Biomed, Kuopio Campus, FI-70211 Kuopio - Finland

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH; v. 18, n. 6 MAR 2021.
• Web of Science Citations: 0

Abstract

This study aimed to identify the mediating effect of lean soft tissue (LST) in the association between somatic maturation and areal bone mineral density (aBMD) in adolescents by sex and sport participation. The sample included 558 adolescents (401 males, mean age of 14.0 years) that were practitioners of sports (11 sport modalities, n = 402) and a non-sport group (n = 157). Somatic maturation was assessed by using a validated peak height velocity prediction equation. Dual-energy X-ray absorptiometry (DXA) was used to assess aBMD (upper and lower limbs, spine and total body less head-TBLH) and LST. For both sexes, LST mediated the association between somatic maturation and aBMD at all skeletal sites (mediation percentage ranging from 36.3% to 75.4%). For sport and non-sport groups, the LST also mediated the association between somatic maturation and aBMD at all skeletal sites (mediation percentage ranging from 51.6% to 85.6%). The direct effect was observed in all groups, except for lower limbs and TBLH in the non-sport group. The association between somatic maturation and aBMD was mediated by LST in adolescents of both sexes and regardless of involvement in organized sports. Our findings highlighted the role of improving LST to mitigate the association of somatic maturation with aBMD. (AU)

• FAPESP's process: 17/09182-5 - Impact of aquatic sport participation on markers of bone turnover among adolescents: ABCD - growth study
• Grantee: Ricardo Ribeiro Agostinete
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 16/20354-0 - Arrangements different impact sports in occurrence and gravity musculoskeletal symptoms among pediatric groups: ABCD growth study
• Grantee: Santiago Maillane Vanegas
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 16/06920-2 - Application allometric models in understanding the relationship between sports practice, biological maturity and bone variable in adolescents
• Grantee: Ricardo Ribeiro Agostinete
• Support Opportunities: Scholarships abroad - Research Internship - Master's degree
• FAPESP's process: 18/24164-6 - LONGITUDINAL ADAPTATIONS IN BONE GEOMETRY AND STRENGTH IN ADOLESCENTS ENGAGED IN SIX DIFFERENT SPORTS: ABCD - GROWTH STUDY
• Grantee: Ricardo Ribeiro Agostinete
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• FAPESP's process: 13/06963-5 - Practice of different sport modalities and bone mass gain in adolescents: cohort of 09 months
• Grantee: Ricardo Ribeiro Agostinete
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 15/13543-8 - Inflammatory mechanisms linking sports practice at high intensity and bone development in young
• Grantee: Ricardo Ribeiro Agostinete
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 15/19710-3 - Analysis of behaviors of children during growth (ABCD - Growth Study)
• Grantee: Rômulo Araújo Fernandes
• Support Opportunities: Regular Research Grants
• FAPESP's process: 17/27234-2 - Longitudinal association between biological maturation, body fatness and sports participation predicting the risk of metabolic syndrome and C-reactive protein: structural equation modelling (ABCD - growth study)
• Grantee: André de Oliveira Werneck
• Support Opportunities: Scholarships in Brazil - Master