Determination of primary aromatic amines from cooking utensils by capillary electrophoresis-tandem mass spectrometry

Author(s)

Favaro Perez, Mary Angela ^{[1, 2]} ; Daniel, Daniela ^[3] ; Padula, Marisa ^[2] ; do Lago, Claudimir Lucio ^[3] ; Grespan Bottoli, Carla Beatriz ^[1]

Affiliation

^[1] Univ Estadual Campinas, Inst Chem, POB 6154, BR-13083970 Campinas, SP - Brazil

^[2] Packaging Technol Ctr Cetea, Inst Food Technol Ital, Av Brasil 2880, BR-13070178 Campinas, SP - Brazil

^[3] Univ Sao Paulo, Inst Chem, Av Prof Lineu Prestes 748, BR-05508000 Sao Paulo, SP - Brazil

• Document type: Journal article
• Source: Food Chemistry; v. 362, NOV 15 2021.
• Web of Science Citations: 0

Abstract

This paper describes a fast, sensitive, environment-friendly method for the determination of 19 primary aromatic amines (PAAs) in cooking utensils by capillary zone electrophoresis coupled with tandem mass spectrometry. The best electrophoretic separation of PAAs was obtained in 0.1 mol l- 1 formic acid (pH 2.4) as the background electrolyte, fused silica capillary (67 cm) with a run time below 6 min. The proposed method presented a linear calibration with correlation coefficients higher than 0.99 and reproducibility in a range of 1-25%. Limits of detection were in the range of 0.2-1.3 mu g kg-1 and recoveries were in a range of 85-120% for all the PAAs. The validated method was employed to determine PAAs on 36 samples of cooking utensils using acetic simulant. The results showed that 4,4 `-diaminodiphenylmethane and aniline being the most frequently found PAAs in these samples and 28% of cooking utensils were not compliant. (AU)

• FAPESP's process: 18/07234-0 - 47th International Symposium on High Perfomance Liquid Phase Separations and Related Techniques
• Grantee: Carla Beatriz Grespan Bottoli
• Support Opportunities: Research Grants - Meeting - Abroad
• FAPESP's process: 14/50867-3 - INCT 2014: National Institute of Science and Technology in Bioanalysis
• Grantee: Marco Aurelio Zezzi Arruda
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 15/26300-6 - Assessment of potential food contamination by primary aromatic amines (PAAs) with focus on kitchenware
• Grantee: Marisa Padula
• Support Opportunities: Regular Research Grants
• FAPESP's process: 12/06642-1 - Formation and properties of adducts of organic hydroxy-compounds with carbonate in aqueous medium and biological conditions
• Grantee: Claudimir Lucio Do Lago
• Support Opportunities: Regular Research Grants