| Full text | |
| Author(s): |
Dolan, Eimear
[1]
;
Warren, Daniel E.
[2]
;
Harris, Roger C.
[3]
;
Sale, Craig
[4]
;
Gualano, Bruno
[5, 1]
;
Saunders, Bryan
[6, 1]
Total Authors: 6
|
| Affiliation: | [1] Univ Sao Paulo, Fac Med FMUSP, Sch Phys Educ & Sport, Rheumatol Div, Appl Physiol & Nutr Res Grp, Sao Paulo, SP - Brazil
[2] St Louis Univ, Dept Biol, St Louis, MO 63103 - USA
[3] Junipa Ltd, Newmarket, Suffolk - England
[4] Nottingham Trent Univ, Sport Hlth & Performance Enhancement Res Ctr, Sch Sci & Technol, Musculoskeletal Physiol Res Grp, Nottingham - England
[5] Univ Sao Paulo, Food Res Ctr, Sao Paulo - Brazil
[6] Univ Sao Paulo, Fac Med FMUSP, Inst Orthopaed & Traumatol, Sao Paulo - Brazil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY; v. 262, DEC 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
Freshwater turtles found in higher latitudes can experience extreme challenges to acid-base homeostasis while overwintering, due to a combination of cold temperatures along with the potential for environmental hypoxia. Histidine-containing dipeptides (HCDs; carnosine, anserine and balenine) may facilitate pH regulation in response to these challenges, through their role as pH buffers. We measured the HCD content of three tissues (liver, cardiac and skeletal muscle) from the anoxia-tolerant painted turtle (C. picta bellii) acclimated to either 3 or 20 degrees C. HCDs were detected in all tissues, with the highest content shown in the skeletal muscle. Turtles acclimated to 3 degrees C had more HCD in their skeletal muscle than those acclimated to 20 degrees C (carnosine = 20.8 +/- 4.5 vs 12.5 +/- 5.9 mmol. kg DM-1; ES = 1.59 (95%CI: 0.16-3.00), P = 0.013). The higher HCD content shown in the skeletal muscle of the cold-acclimated turtles suggests a role in acid-base regulation in response to physiological challenges associated with living in the cold, with the increase possibly related to the temperature sensitivity of carnosine's dissociation constant. (AU) | |
| FAPESP's process: | 19/26899-6 - The bone response to exercise a translational research program exploring clinical and mechanistic aspects |
| Grantee: | Eimear Bernadette Dolan |
| Support Opportunities: | Scholarships in Brazil - Young Researchers |
| FAPESP's process: | 17/13552-2 - Reducing sedentary time in clinical populations: the take a stand for health study |
| Grantee: | Bruno Gualano |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 16/50438-0 - Nutritional suplementation and exercise to optimize exercise performance: focus on individual responses and a step towards personalized sports nutrition |
| Grantee: | Bryan Saunders |
| Support Opportunities: | Research Grants - Young Investigators Grants |
| FAPESP's process: | 19/05616-6 - The bone response to exercise: a translational research program exploring clinical and mechanistic aspects |
| Grantee: | Eimear Bernadette Dolan |
| Support Opportunities: | Research Grants - Young Investigators Grants |