Comparison of two types of xenogeneic matrices to treat single gingival recessions: A randomized clinical trial

Author(s)

Santamaria, Mauro Pedrine ^{[1, 2]} ; Rossato, Amanda ^[2] ; Viana Miguel, Manuela Maria ^[2] ; Fonseca, Manuela Bafini ^[2] ; Gomez Bautista, Cristhian Reynaldo ^[2] ; Marco, Andrea Carvalho ^[2] ; Mathias-Santamaria, Ingrid Fernandes ^{[3, 2]} ; Ferreira Ferraz, Lais Fernanda ^[2]

Affiliation

^[1] Univ Kentucky, Coll Dent Lexington, Lexington, KY - USA

^[2] Sao Paulo State Univ Unesp, Inst Sci & Technol, Div Periodont, Av Engn Francisco Jose Longo 777, Sao Jose Dos Campos, SP - Brazil

^[3] Univ Maryland, Sch Dent, Div Operat Dent, Dept Gen Dent, Baltimore, MD 21201 - USA

• Document type: Journal article
• Source: Journal of Periodontology; NOV 2021.
• Web of Science Citations: 0

Abstract

Background Xenogeneic matrices (XMs) have been increasingly used for root coverage procedures. This study compared the use of two types of XM (collagen matrix {[}CM] and xenogeneic acellular dermal matrix {[}XDM]) associated with the coronally advanced flap technique (CAF) to treat single gingival recessions. Methods Seventy-five patients presenting single RT1 gingival recession were treated by CAF (control group, n = 25), CAF+CM (test group 1, n = 25), or CAF+XDM (test group 2, n = 25) and completed 6-month follow-up. Clinical, patient-centered, and esthetic assessments were performed and intra- and intergroup differences were analyzed. Results At 6 months, the mean recession reduction for CAF, CAF+CM, and CAF+XDM was 2.4 +/- 0.8 mm, 2.4 +/- 0.9 mm and 2.1 +/- 0.8 mm, respectively (P > 0.05). The corresponding mean percentage of root coverage was 78.9% +/- 26.2% for CAF, 78.0% +/- 28.5% for CAF+CM, and 65.6% +/- 26.9% for CAF+XDM (P > 0.05). Dentin hypersensitivity and esthetic conditions showed significantly improvements in all groups. Test groups presented significant gains in gingival thickness (GT; CAF+CM: 0.4 +/- 0.3 mm; CAF+XDM: 0.4 +/- 0.2 mm) compared to the control group (CAF: 0.0 +/- 0.1 mm; P < 0.05). Conclusion The CAF, CAF+CM, and CAF+XDM treatments each provided similar results in the treatment of single gingival recessions. The addition of either CM or XDM to CAF increases the GT. (AU)

• FAPESP's process: 18/03284-3 - Comparison between porcine acellular dermal matrix (Mucoderm®) versus connective tissue graft in the treatment of multiple gingival recessions associated with non-carious cervical lesion partially restored: randomized clinical trial
• Grantee: Amanda Rossato
• Support Opportunities: Scholarships in Brazil - Master