| Full text | |
| Author(s): |
da Silva, Jonas Joaquim Mangabeira
[1]
;
Campanharo, Sarah Chagas
[1]
;
Paschoal, Jonas Augusto Rizzato
[1]
Total Authors: 3
|
| Affiliation: | [1] Univ Sao Paulo, Dept Biomol Sci, Sch Pharmaceut Sci Ribeirao Preto, Ave Cafe S-N, BR-14040903 Ribeirao Preto, SP - Brazil
Total Affiliations: 1
|
| Document type: | Review article |
| Source: | COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY; v. 20, n. 1, p. 48-90, JAN 2021. |
| Web of Science Citations: | 3 |
| Abstract | |
Alternatives to the use of conventional veterinary drugs in food-producing animals have gained attention, such as the use of natural products (NPs), mainly to soften the risks to the animal, the environment, and consumer's health. Although NPs have consistent advantages over conventional drugs, they cannot be considered risk free under food safety matters. In this way, this document presents a comprehensive overview of the importance of considering both the pharmacological and toxicological properties of the constituents of a NP from plants intending the standardization and regulation of its use in food-producing animals. Terpenes are the most diverse class of natural substances present in NP of vegetal origin with a broad range of biological activities that can be explored in veterinary science; however, certain plants and terpenes also have significant toxic effects, a fact that can harm the health of animals and consequently generate economic losses and risks for humans. In this context, this review gathered scientific data of vegetal species of importance to ethnoveterinary for food-producing animals, which produce terpenes, its biological effects, and their implications on food safety issues for consumers. For this, more than 300 documents were selected from different online scientific databases. The present data and discussion may contribute to the rational commercial exploration of this class of NPs in veterinary medicine. (AU) | |
| FAPESP's process: | 19/06159-8 - Studies for the safe use of erythromycin and doxycycline in fish of national commercial importance |
| Grantee: | Jonas Augusto Rizzato Paschoal |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 17/15052-7 - Residual persistence investigation of toxic constituents of C. duckei used in Pisciculture |
| Grantee: | Jonas Joaquim Mangabeira da Silva |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 18/05536-0 - Erythromycin in aquaculture: studies for drug incorporation in feed and for residual depletion in fish |
| Grantee: | Sarah Chagas Campanharo |
| Support Opportunities: | Scholarships in Brazil - Master |
| FAPESP's process: | 12/18334-0 - Veterinary drug residues in food: multiclass analytical methods employing LC-MS/MS, exposition data and residual depletion study |
| Grantee: | Jonas Augusto Rizzato Paschoal |
| Support Opportunities: | Research Grants - Young Investigators Grants |