| Full text | |
| Author(s): Show less - |
Marcelino, Gabriela
;
Hiane, Priscila Aiko
;
Pott, Arnildo
;
de Oliveira Filiu, Wander Fernando
;
Caires, Anderson R. L.
;
Michels, Flavio S.
;
Junior, Mario R. Marostica
;
Santos, Nathalia M. S.
;
Nunes, Angela A.
;
Oliveira, Lincoln C. S.
;
Cortes, Mario R.
;
Maldonade, Iriani R.
;
Cavalheiro, Leandro F.
;
Nazario, Carlos Eduardo Domingues
;
Santana, Lidiani Figueiredo
;
Di Pietro Fernandes, Carolina
;
Negrao, Fabio Juliano
;
Tatara, Mariana Bento
;
de Faria, Bernardo Bacelar
;
Asato, Marcel Arakaki
;
de Cassia Freitas, Karine
;
Bogo, Danielle
;
do Nascimento, Valter Aragao
;
de Cassia Avellaneda Guimaraes, Rita
Total Authors: 24
|
| Document type: | Journal article |
| Source: | NUTRIENTS; v. 14, n. 12, p. 22-pg., 2022-06-01. |
| Abstract | |
Mauritia flexuosa (Buriti) pulp oil contains bioactive substances and lipids that are protective against cardiovascular and inflammatory diseases. We performed physical and chemical analyses to verify its quality and stability. Buriti oil was stable according to the Rancimat test, presenting an induction period of 6.6 h. We evaluated the effect of supplementation with crude buriti oil and olive oil on metabolic parameters in 108 Swiss mice for 90 days. We investigated six groups: extra virgin olive oil (EVOO) 1 and 2 (1000 and 2000 mg/kg), buriti oil (BO) 1 and 2 (1000 and 2000 mg/kg), synergic (S) (BO1 + EVOO1), and control (water dose 1000 mg/kg). The animals were euthanized to examine their blood, livers, and fats. The supplementation did not interfere with food consumption, weight gain, and histological alterations in the liver. Group S showed the strongest relationship with the fractions HDL-c and non-HDL-c, indicating a possible cardioprotective effect. Moreover, we observed significantly higher IL-6 levels in the control, EVOO2, and BO1 groups than in the EVOO1 group. Resistin was also significantly higher for the synergic treatment than for the control. We conclude that BO combined with EVOO could be an excellent food supplement for human consumption. (AU) | |
| FAPESP's process: | 15/50333-1 - COBRA: a novel compound discovery pipeline for rapid and cost-effective identification of bioactives with health beneficial effects in Brazilian crops |
| Grantee: | Glaucia Maria Pastore |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 15/13320-9 - Effect of pulp oil and tea of leaves from avocado Hass variety associated with physical activity in the treatment of obesity induced by high-fat diet |
| Grantee: | Mário Roberto Maróstica Junior |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 18/11069-5 - Action of Brazilian berries on metabolic parameters and cognitive performance of obese animals |
| Grantee: | Mário Roberto Maróstica Junior |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 19/13465-8 - Lund University and State University of Campinas partnership for studies on cardiometabolic disease-preventive functional foods and diets |
| Grantee: | Mário Roberto Maróstica Junior |
| Support Opportunities: | Regular Research Grants |