Action of Brazilian berries on metabolic parameters and cognitive performance of obese animals

• Grant number: 18/11069-5
• Support Opportunities: Regular Research Grants
• Duration: June 01, 2019 - January 31, 2022
• Field of knowledge: Health Sciences - Nutrition - Nutrition Biochemistry
• Principal Investigator: Mário Roberto Maróstica Junior
• Grantee: Mário Roberto Maróstica Junior
• Host Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated grant(s): 19/13465-8 - Lund University and State University of Campinas partnership for studies on cardiometabolic disease-preventive functional foods and diets, AP.R SPRINT

Abstract

Brazil has the most diverse flora in the world, which favors the discovery of edible vegetable tissues rich in bioactive compounds. The grumixama (Eugenia brasiliensis Lam.) and the cherry-of-the-rio-grande (Eugenia involucrata DC.) represent sources of phenolic compounds that may potentially contribute to the prevention and treatment of chronic noncommunicable diseases such as obesity and associated comorbidities. The aim of this study is to evaluate the chemical composition and bioactivity of two Brazilian native fruits (grumixama and cherry-of-the-rio-grande) as regards anti-inflammatory, antioxidant, anti-obesogenic and neuroprotective capacity in obese animals. Swiss mice will be induced to develop obesity through a hyperlipid diet rich in saturated fatty acids. The animals will receive the lyophilized fruits (bark + pulp) added to the diets which will be fed ad libitum throughout the experimental period. The biological functionality of compounds from both fruits will be analyzed based on the determination of body weight and composition, lipid profile, hormone profile associated with hunger and satiety, insulin resistance level, serum adipokines, inflammation and oxidative stress, as well as through neurodegeneration and cognition task. The results will be analyzed by applying analysis of variance ANOVA and Tukey test for parametric data and Kruskal Wallis for non-parametric data, considering p < 0.05. The project will be executed between the first half of 2019 and the second semester of 2021. (AU)

Scientific publications

(46)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ARRUDA, HENRIQUE SILVANO; NERI-NUMA, IRAMAIA ANGELICA; KIDO, LARISSA AKEMI; MAROSTICA JUNIOR, MARIO ROBERTO; PASTORE, GLAUCIA MARIA. Recent advances and possibilities for the use of plant phenolic compounds to manage ageing-related diseases. Journal of Functional Foods, v. 75, DEC 2020. (18/11069-5, 15/13320-9, 17/01573-5, 15/50333-1)

KIDO, LARISSA AKEMI; HAHM, EUN-RYEONG; KIM, SU-HYEONG; BASEGGIO, ANDRESSA MARA; CAGNON, VALERIA HELENA ALVES; SINGH, SHIVENDRA V.; MAROSTICA, JR., MARIO ROBERTO. Prevention of Prostate Cancer in Transgenic Adenocarcinoma of the Mouse Prostate Mice by Yellow Passion Fruit Extract and Antiproliferative Effects of Its Bioactive Compound Piceatannol. JOURNAL OF CANCER PREVENTION, v. 25, n. 2, p. 87-99, JUN 2020. (18/11069-5, 15/13320-9, 15/50333-1, 18/09793-7)

ARRUDA, HENRIQUE SILVANO; SILVA, ERIC KEVEN; PEIXOTO ARAUJO, NAYARA MACEDO; PEREIRA, GUSTAVO ARAUJO; PASTORE, GLAUCIA MARIA; MAROSTICA JUNIOR, MARIO ROBERTO. Anthocyanins Recovered from Agri-Food By-Products Using Innovative Processes: Trends, Challenges, and Perspectives for Their Application in Food Systems. Molecules, v. 26, n. 9, MAY 2021. (19/27103-0, 19/13465-8, 18/11069-5, 18/10608-0, 15/13320-9, 15/50333-1)

REBELO, KEMILLA SARMENTO; COIMBRA NUNEZ, CARLA EVELYN; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, MARIO ROBERTO; KRISTIANSEN, KARSTEN; DANNESKIOLD-SAMSOE, NIELS BANHOS. Pot-pollen supplementation reduces fasting glucose and modulates the gut microbiota in high-fat/high-sucrose fed C57BL/6 mice. FOOD & FUNCTION, v. 13, n. 7, p. 11-pg., 2022-03-15. (15/13320-9, 15/50333-1, 19/13465-8, 18/11069-5)

KIDO, LARISSA AKEMI; ROSSETTO, ISABELA MARIA URRA; BASEGGIO, ANDRESSA MARA; CHIAROTTO, GABRIELA BORTOLANZA; ALVES, LETICIA FERREIRA; SANTOS, FELIPE RABELO; LAMAS, CELINA DE ALMEIDA; MAROSTICA, MARIO ROBERTO; CAGNON, VALERIA HELENA ALVES. Brazilian Berry Extract Differentially Induces Inflammatory and Immune Responses in Androgen Dependent and Independent Prostate Cancer Cells. JOURNAL OF CANCER PREVENTION, v. 27, n. 3, p. 10-pg., 2022-09-30. (18/04579-7, 15/50333-1, 19/13465-8, 15/13320-9, 18/11069-5)

LONGO, MARJORIE BARCHA; LAMAS, CELINA DE ALMEIDA; ROSSETTO, ISABELA URRA; NOGUEIRA-LIMA, ELLEN; COLLARES-BUSATTO, CARLA BEATRIZ; MAROSTICA JUNIOR, MARIO ROBERTO; ALVES CAGNON QUITETE, VALERIA HELENA. Brazilian Berry Extract Chemopreventive Action: Hormone Receptors as a Target to Mitigate Aging Prostatic Disorders.. Brazilian Archives of Biology and Technology, v. 66, p. 12-pg., 2023-01-01. (15/25714-1, 15/13320-9, 18/11069-5, 15/24793-5, 18/04579-7, 15/50333-1)

CAETANO, PATRICIA A.; DO NASCIMENTO, TATIELE C.; FERNANDES, ANDRESSA S.; NASS, PRICILA P.; VIEIRA, KAREM R.; MAROSTICA JUNIOR, MARIO R.; JACOB-LOPES, EDUARDO; ZEPKA, LEILA Q.. Microalgae-based polysaccharides: Insights on production, applications, analysis, and future challenges. BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY, v. 45, p. 18-pg., 2022-10-01. (19/13465-8, 15/50333-1, 18/11069-5, 15/13320-9)

ARRUDA, HENRIQUE SILVANO; SILVA, ERIC KEVEN; PASTORE, GLAUCIA MARIA; MAROSTICA, MARIO ROBERTO. Non-Thermal Supercritical Carbon Dioxide Processing Retains the Quality Parameters and Improves the Kinetic Stability of an Araticum Beverage Enriched with Inulin-Type Dietary Fibers. FOODS, v. 12, n. 13, p. 21-pg., 2023-07-01. (23/01876-9, 15/13320-9, 15/50333-1, 19/13465-8, 20/08761-4, 18/11069-5)

PECANHA, JULIANA DE SOUZA; DOS SANTOS, NATHALIA MEDINA; MAROSTICA JUNIOR, MARIO ROBERTO; MICHELETTI, ANA CAMILA; LIAO, LUCIANO MORAIS; ALCANTARA, GLAUCIA BRAZ. NMR-based metabolomics of dried berries in comparison with dietary supplements. Journal of Pharmaceutical and Biomedical Analysis, v. 209, FEB 5 2022. (15/13320-9, 18/11069-5, 19/13465-8, 15/50333-1)

BASEGGIO, ANDRESSA MARA; KIDO, LARISSA AKEMI; VIGANO, JULIANE; CARNEIRO, MARA JUNQUEIRA; LAMAS, CELINA DE ALMEIDA; MARTINEZ, JULIAN; SAWAYA, ALEXANDRA CHRISTINE HELENA FRANKLAND; CAGNON, VALERIA HELENA ALVES; MAROSTICA JUNIOR, MARIO ROBERTO. Systemic antioxidant and anti-inflammatory effects of yellow passion fruit bagasse extract during prostate cancer progression. JOURNAL OF FOOD BIOCHEMISTRY, AUG 2021. (17/01573-5, 18/11069-5, 15/13320-9, 15/50333-1, 19/13465-8)

REGUENGO, LIVIA MATEUS; SALGACO, MATEUS KAWATA; SIVIERI, KATIA; MAROSTICA JUNIOR, MARIO ROBERTO. gro-industrial by-products: Valuable sources of bioactive compound. Food Research International, v. 152, FEB 2022. (15/50333-1, 19/25048-2, 18/11069-5, 15/13320-9)

DO NASCIMENTO, ROBERTO DE PAULA; REGUENGO, LIVIA MATEUS; DA FONSECA MACHADO, ANA PAULA; MAROSTICA JUNIOR, MARIO ROBERTO. he preventive and therapeutic potential of native Brazilian fruits on colorectal cance. FOOD BIOSCIENCE, v. 46, APR 2022. (18/11069-5, 19/03228-9, 17/23657-6, 15/50333-1, 19/25048-2, 15/13320-9)

BATISTA, ANGELA GIOVANA; MENDONCA, MONIQUE CULTURATO P.; SOARES, EDILENE SIQUEIRA; DA SILVA-MAIA, JULIANA KELLY; DIONISIO, ANA PAULA; SARTORI, CESAR R.; DA CRUZ-HOFLING, MARIA ALICE; MAROSTICA JUNIOR, MARIO ROBERTO. Syzygium malaccense fruit supplementation protects mice brain against high-fat diet impairment and improves cognitive functions. Journal of Functional Foods, v. 65, FEB 2020. (18/11069-5, 15/50333-1)

SOUZA, ALANN THAFFARELL PORTILHO; FREITAS, GILEADE PEREIRA; LOPES, HELENA BACHA; TOTOLI, GABRIELA GUARALDO CAMPOS; TARONE, ADRIANA GADIOLI; MAROSTICA-JUNIOR, MARIO ROBERTO; ROSA, ADALBERTO LUIZ; BELOTI, MARCIO MATEUS. Jabuticaba peel extract modulates adipocyte and osteoblast differentiation of MSCs from healthy and osteoporotic rats. JOURNAL OF BONE AND MINERAL METABOLISM, v. 39, n. 2, SEP 2020. (15/13320-9, 17/20349-9, 18/11069-5, 15/50333-1, 17/12622-7)

MARCELINO, GABRIELA; HIANE, PRISCILA AIKO; POTT, ARNILDO; DE OLIVEIRA FILIU, WANDER FERNANDO; CAIRES, ANDERSON R. L.; MICHELS, FLAVIO S.; JUNIOR, MARIO R. MAROSTICA; SANTOS, NATHALIA M. S.; NUNES, ANGELA A.; OLIVEIRA, LINCOLN C. S.; et al. Characterization of Buriti (Mauritia flexuosa) Pulp Oil and the Effect of Its Supplementation in an In Vivo Experimental Model. NUTRIENTS, v. 14, n. 12, p. 22-pg., 2022-06-01. (15/50333-1, 15/13320-9, 18/11069-5, 19/13465-8)

VALLE, MARIA C. P. R.; VIEIRA, ISABEL A.; FINO, LUCIANA C.; GALLINA, DARLILA A.; ESTEVES, ANDREA M.; DA CUNHA, DIOGO T.; CABRAL, LUCELIA; BENATTI, FABIANA B.; MAROSTICA JUNIOR, MARIO R.; BATISTA, ANGELA G.; et al. Immune status, well-being and gut microbiota in military supplemented with synbiotic ice cream and submitted to field training: a randomised clinical trial. BRITISH JOURNAL OF NUTRITION, v. 126, n. 12, p. 1794-1808, DEC 28 2021. (18/18366-5, 15/50333-1, 17/25007-9, 18/11069-5, 15/13320-9)

MOREIRA, RAFAEL CHELALA; DE MELO, RAYANNE PRISCILLA FRANCA; MARTINEZ, JULIAN; MAROSTICA JUNIOR, MARIO ROBERTO; PASTORE, GLAUCIA MARIA; ZORN, HOLGER; BICAS, JULIANO LEMOS. Supercritical CO2 as a Valuable Tool for Aroma Technology. Journal of Agricultural and Food Chemistry, v. 71, n. 24, p. 12-pg., 2023-06-08. (21/01008-1, 15/13320-9, 20/06814-3, 17/11245-5, 15/50333-1, 19/13465-8, 18/11069-5)

BERILLI, PATRICIA; FANARO, GUSTAVO BERNARDES; SANTOS, JESSICA PIVA; REYES, FELIX GUILLERMO REYES; IGLESIAS, AMADEU HOSHI; REIS, MARCELLA; CAZARIN, CINTHIA BAUL BETIM; MAROSTICA JUNIOR, MARIO ROBERTO. White tea modulates antioxidant defense of endurance-trained rats. CURRENT RESEARCH IN PHYSIOLOGY, v. 5, p. 9-pg., 2022-01-01. (15/50333-1, 18/11069-5)

DO NASCIMENTO, ROBERTO DE PAULA; MOYA, AMANDA MARIA TOMAZINI MUNHOZ; MACHADO, ANA PAULA DA FONSECA; GERALDI, MARINA VILAR; DIEZ-ECHAVE, PATRICIA; VEZZA, TERESA; GALVEZ, JULIO; CAZARIN, CINTHIA BAIL BETIM; MAROSTICA, JR., MARIO ROBERTO. Review on the potential application of non-phenolic compounds from native Latin American food byproducts in inflammatory bowel diseases. Food Research International, v. 139, JAN 2021. (15/50333-1, 15/13320-9, 19/12244-8, 17/23657-6, 18/11069-5)

LAMAS, CELINA A.; KIDO, LARISSA A.; HERMES, TULIO A.; NOGUEIRA-LIMA, ELLEN; MINATEL, ELAINE; COLLARES-BUZATO, CARLA B.; MAROSTICA JR, MARIO R.; CAGNON, VALERIA H. A.. Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress. PROSTATE, v. 80, n. 11, p. 13-pg., 2020-05-27. (15/50333-1, 15/25714-1, 18/11069-5)

DO NASCIMENTO, ROBERTO DE PAULA; RIZZATO, JULIA SOTO; POLEZI, GABRIELE; MOYA, AMANDA MARIA TOMAZINI MUNHOZ; SILVA, MILENA FERREIRA; MACHADO, ANA PAULA DA FONSECA; FRANCHI JUNIOR, GILBERTO CARLOS; BORGUINI, RENATA GALHARDO; SANTIAGO, MANUELA CRISTINA PESSANHA DE ARAUJO; PAIOTTI, ANA PAULA RIBEIRO; et al. Freeze-dried jaboticaba (Myrciaria jaboticaba) peel powder, a rich source of anthocyanins and phenolic acids, mitigates inflammation-driven colorectal cancer in mice. FOOD BIOSCIENCE, v. 53, p. 10-pg., 2023-04-05. (15/13320-9, 20/00414-3, 19/03228-9, 15/50333-1, 17/23657-6, 18/11069-5)

DE OLIVEIRA, ELLEN CRISTINA SOUZA; DALMAU, LESVI MOYA; DE ALMEIDA COSTA, CELSO ACACIO RODRIGUES; DE ALMEIDA JUNIOR, LUIZ DOMINGUES; BALLARD, CINTIA REIS; MAROSTICA JUNIOR, MARIO ROBERTO; STAHL, MARCELLA APARECIDA; GRIMALDI, RENATO; WITAICENIS, ALINE; DI STASI, LUIZ CLAUDIO. Dietary intervention with avocado (Persea americana Mill.) ameliorates intestinal inflammation induced by TNBS in rats. INFLAMMOPHARMACOLOGY, v. N/A, p. 14-pg., 2022-12-31. (19/13465-8, 15/50333-1, 18/11069-5, 15/13320-9)

MEDINA DOS SANTOS, NATHALIA; BATISTA, ANGELA GIOVANA; MENDONCA, MONIQUE CULTURATO PADILHA; ANGOLINI, CELIO FERNANDO FIGUEIREDO; GRIMALDI, RENATO; PASTORE, GLAUCIA MARIA; SARTORI, CESAR RENATO; DA CRUZ-HOEFLING, MARIA ALICE; MAROSTICA JR, MARIO ROBERTO. Acai pulp improves cognition and insulin sensitivity in obese mice. NUTRITIONAL NEUROSCIENCE, v. N/A, p. 11-pg., 2023-01-06. (15/50333-1, 18/11069-5)

DE PAULA DO NASCIMENTO, ROBERTO; DA FONSECA MACHADO, ANA PAULA; GALVEZ, JULIO; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, MARIO ROBERTO. Ulcerative colitis: Gut microbiota, immunopathogenesis and application of natural products in animal models. Life Sciences, v. 258, p. 22-pg., 2020-10-01. (17/23657-6, 15/13320-9, 18/11069-5, 15/50333-1)

REGUENGO, LIVIA MATEUS; DO NASCIMENTO, ROBERTO DE PAULA; MACHADO, ANA PAULA DA FONSECA; MAROSTICA JUNIOR, MARIO ROBERTO. Signaling pathways and the potential anticarcinogenic effect of native Brazilian fruits on breast cancer. Food Research International, v. 155, p. 13-pg., 2022-05-01. (15/13320-9, 18/11069-5, 19/03228-9, 17/23657-6, 15/50333-1, 19/25048-2, 19/12244-8)

GERALDI, MARINA VILAR; BETIM CAZARIN, CINTHIA BAU; DIAS-AUDIBERT, FLAVIA LUISA; PEREIRA, GUSTAVO ARAUJO; CARVALHO, GABRIELA GUIMARAES; KABUKI, DIRCE YORIKA; CATHARINO, RODRIGO RAMOS; PASTORE, GLAUCIA MARIA; BEHRENS, JORGE HERMAN; CRISTIANINI, MARCELO; et al. Influence of high isostatic pressure and thermal pasteurization on chemical composition, color, antioxidant properties and sensory evaluation of jabuticaba juice. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 139, MAR 2021. (15/50333-1, 18/11069-5, 19/12244-8, 15/13320-9)

AGUIAR, LAIS MARINHO; BICAS, JULIANO LEMOS; FUENTES, EDUARDO; ALARCON, MARCELO; GONZALEZ, IVAN PALOMO; PASTORE, GLAUCIA MARIA; MAROSTICA JUNIOR, MARIO ROBERTO; CAZARIN, CINTHIA BAU BETIM. Non-nutrients and nutrients from Latin American fruits for the prevention of cardiovascular diseases. Food Research International, v. 139, JAN 2021. (18/11069-5, 15/50333-1, 15/13320-9)

MACHADO, ANA PAULA DA FONSECA; ALVES, MARIANA DA ROCHA; NASCIMENTO, ROBERTO DE PAULA DO; REGUENGO, LIVIA MATEUS; MAROSTICA JR, MARIO ROBERTO. Antiproliferative effects and main molecular mechanisms of Brazilian native fruits and their by-products on lung cancer. Food Research International, v. 162, p. 9-pg., 2022-12-01. (17/23657-6, 19/03228-9, 15/50333-1, 19/12244-8, 15/13320-9, 18/11069-5)

BARROS MARIUTTI, LILIAN REGINA; REBELO, KEMILLA SARMENTO; BISCONSIN-JUNIOR, ANTONIO; DE MORAIS, JANNE SANTOS; MAGNANI, MARCIANE; MALDONADE, IRIANI RODRIGUES; MADEIRA, NUNO RODRIGO; TIENGO, ANDREA; MAROSTICA, JR., MARIO ROBERTO; BETIM CAZARIN, CINTHIA BAU. The use of alternative food sources to improve health and guarantee access and food intake. Food Research International, v. 149, NOV 2021. (19/13465-8, 18/11069-5, 15/50333-1, 15/13320-9)

LAIBER PASCOAL, GABRIELA DE FREITAS; DE ALMEIDA SOUSA CRUZ, MARTA ANGELA; DE ABREU, JOEL PIMENTEL; BARROS SANTOS, MILLENA CRISTINA; FANARO, GUSTAVO BERNARDES; MAROSTICA JUNIOR, MARIO ROBERTO; SILVA, OTNIEL FREITAS; ALVES MOREIRA, RICARDO FELIPE; CAMERON, LUIZ CLAUDIO; LARRAZ FERREIRA, MARIANA SIMOES; et al. Evaluation of the antioxidant capacity, volatile composition and phenolic content of hybrid Vitis vinifera L. varieties sweet sapphire and sweet surprise. Food Chemistry, v. 366, JAN 1 2022. (19/13465-8, 18/11069-5, 15/50333-1, 15/13320-9)

LAMAS, CELINA A.; KIDO, LARISSA A.; HERMES, TULIO A.; NOGUEIRA-LIMA, ELLEN; MINATEL, ELAINE; COLLARES-BUZATO, CARLA B.; MAROSTICA JR, MARIO R.; CAGNON, VALERIA H. A.. Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress. PROSTATE, v. 80, n. 11, MAY 2020. (18/11069-5, 15/50333-1, 15/25714-1)

MACHADO, ANA PAULA DA FONSECA; DO NASCIMENTO, ROBERTO DE PAULA; ALVES, MARIANA DA ROCHA; REGUENGO, LIVIA MATEUS; MAROSTICA JUNIOR, MARIO ROBERTO. razilian tucuma-do-Amazonas (Astrocaryum aculeatum) and tucuma-do-Para (Astrocaryum vulgare) fruits: bioactive composition, health benefits, and technological potentia. Food Research International, v. 151, JAN 2022. (18/11069-5, 19/25048-2, 19/03228-9, 17/23657-6, 15/50333-1, 15/13320-9)

DE PAULA DO NASCIMENTO, ROBERTO; DA FONSECA MACHADO, ANA PAULA; LIMA, VERENA SILVA; TOMAZINI MUNHOZ MOYA, AMANDA MARIA; REGUENGO, LIVIA MATEUS; BOGUSZ JUNIOR, STANISLAU; LEAL, RAQUEL FRANCO; CAO-NGOC, PHU; ROSSI, JEAN CHRISTOPHE; LECLERCQ, LAURENT; et al. Chemoprevention with a tea from hawthorn (Crataegus oxyacantha) leaves and flowers attenuates colitis in rats by reducing inflammation and oxidative stress. FOOD CHEMISTRY-X, v. 12, DEC 30 2021. (15/50333-1, 15/13320-9, 18/11069-5, 17/23657-6)

SANZANA, SIGRID; RODRIGUEZ, LYANNE; BARRAZA BARRIONUEVO, HAYLEEN; ALBORNOZ POBLETE, CESAR; MAROSTICA JUNIOR, MARIO ROBERTO; FUENTES, EDUARDO; PALOMO, IVAN. ntiplatelet Activity of Cucurbita maxim. JOURNAL OF MEDICINAL FOOD, AUG 2021. (18/11069-5, 15/50333-1, 15/13320-9)

BALLARD, CINTIA R.; GALVAO, TAIS F.; CAZARIN, CINTHIA B. B.; MAROSTICA JR, MARIO R.. Effects of Polyphenol-Rich Fruit Extracts on Diet-Induced Obesity in Rodents: Systematic Review and Meta-Analysis. CURRENT PHARMACEUTICAL DESIGN, v. 25, n. 32, p. 3484-3497, 2019. (18/11069-5, 15/50333-1)

FUENTES, EDUARDO; TROSTCHANSKY, ANDRES; REGUENGO, LIVIA M.; JUNIOR, MARIO R. M.; PALOMO, IVAN. Antiplatelet Effects of Bioactive Compounds Present in Tomato Pomace. CURRENT DRUG TARGETS, v. 22, n. 15, p. 1716-1724, 2021. (18/11069-5, 15/50333-1, 15/13320-9)

QUATRIN, ANDREIA; RAMPELOTTO, CRISTINE; PAULETTO, ROBERSON; MAURER, LUANA HASELEIN; NICHELLE, SABRINA MARAFIGA; KLEIN, BRUNA; RODRIGUES, RENATA FRITZSCHE; MAROSTICA JUNIOR, MARIO ROBERTO; FONSECA, BRUNA DE SOUZA; DE MENEZES, CRISTIANO RAGAGNIN; et al. Bioaccessibility and catabolism of phenolic compounds from jaboticaba (Myrciaria trunciflora) fruit peel during in vitro gastrointestinal digestion and colonic fermentation. Journal of Functional Foods, v. 65, FEB 2020. (18/11069-5, 15/50333-1)

ALEXANDRINO, THAIS DOLFINI; TOMAZINI MUNHOZ MOYA, AMANDA MARIA; MADUREIRA DE MEDEIROS, TIAGO DANIEL; MORARI, JOSEANE; VELLOSO, LICIO AUGUSTO; LEAL, RAQUEL FRANCO; MAROSTICA, MARIO ROBERTO; PASTORE, GLAUCIA MARIA; BETIM CAZARIN, CINTHIA BAU; BICAS, JULIANO LEMOS. Anti-inflammatory effects of monoterpenoids in rats with TNBS-induced colitis. PHARMANUTRITION, v. 14, DEC 2020. (16/21619-7, 15/50333-1, 15/13320-9, 18/11069-5)

VUOLO, MILENA MORANDI; LIMA, GLAUCIA CARIELO; BATISTA, ANGELA GIOVANA; BETIM CARAZIN, CINTHIA BAU; CINTRA, DENNYS ESPER; PRADO, MARCELO ALEXANDRE; MAROSTICA JUNIOR, MARIO ROBERTO. Passion fruit peel intake decreases inflammatory response and reverts lipid peroxidation and adiposity in diet-induced obese rats. Nutrition Research, v. 76, p. 106-117, APR 2020. (18/11069-5, 12/12322-0, 15/50333-1)

ARRUDA, HENRIQUE SILVANO; LOPES ARAUJO, MARIA VITORIA; MAROSTICA JUNIOR, MARIO ROBERTO. Underexploited Brazilian Cerrado fruits as sources of phenolic compounds for diseases management: A review. FOOD CHEMISTRY: MOLECULAR SCIENCES, v. 5, p. 22-pg., 2022-11-23. (15/13320-9, 20/08761-4, 18/11069-5, 19/13465-8, 15/50333-1)

DA SILVA-MAIA, JULIANA KELLY; NAGALINGAM, ARUMUGAM; CAZARIN, CINTHIA BAIL BETIM; MAROSTICA JR, MARIO ROBERTO; SHARMA, DIPALI. Jaboticaba (Myrciaria jaboticaba) peel extracts induce reticulum stress and apoptosis in breast cancer cells. FOOD CHEMISTRY: MOLECULAR SCIENCES, v. 6, p. 8-pg., 2023-02-26. (19/13465-8, 15/50333-1, 18/11069-5, 15/13320-9)

PASCOAL, GABRIELA DE FREITAS LAIBER; GERALDI, MARINA VILAR; MAROSTICA, MARIO ROBERTO, JR.; ONG, THOMAS PRATES. Effect of Paternal Diet on Spermatogenesis and Offspring Health: Focus on Epigenetics and Interventions with Food Bioactive Compounds. NUTRIENTS, v. 14, n. 10, p. 18-pg., 2022-05-01. (15/13320-9, 18/11069-5, 19/13465-8, 15/50333-1, 19/12244-8, 13/07914-8)

MACHADO, ANA PAULA DA FONSECA; GERALDI, MARINA VILAR; NASCIMENTO, ROBERTO DE PAULA DO; MOYA, AMANDA MARIA TOMAZINI MUNHOZ; VEZZA, TERESA; DIEZ-ECHAVE, PATRICIA; JUAN GALVAZ, JULIO; CAZARIN, CINTHIA BAU BETIM; MAROSTICA JUNIOR, MARIO ROBERTO. Polyphenols from food by-products: An alternative or complementary therapy to IBD conventional treatments. Food Research International, v. 140, FEB 2021. (18/11069-5, 19/12244-8, 15/50333-1, 17/23657-6)

DO NASCIMENTO, ROBERTO DE PAULA; POLEZI, GABRIELE; RIZZATO, JULIA SOTO; BATISTA, PATRICIA BERILLI; DOS SANTOS, NATHALIA MEDINA; LOUBET FILHO, PAULO SERGIO; REGUENGO, LIVIA MATEUS; MORARI, JOSEANE; JUNIOR, STANISLAU BOGUSZ; RIBEIRO PAIOTTI, ANA PAULA; et al. Brazilian berries prevent colitis induced in obese mice by reducing the clinical signs and intestinal damage. FOOD BIOSCIENCE, v. 44, n. B, DEC 2021. (15/50333-1, 15/13320-9, 18/11069-5)

ARRUDA, HENRIQUE SILVANO; BORSOI, FELIPE TECCHIO; ANDRADE, AMANDA CRISTINA; PASTORE, GLAUCIA MARIA; MAROSTICA JUNIOR, MARIO ROBERTO. Scientific Advances in the Last Decade on the Recovery, Characterization, and Functionality of Bioactive Compounds from the Araticum Fruit (Annona crassiflora Mart.). PLANTS-BASEL, v. 12, n. 7, p. 39-pg., 2023-04-01. (15/13320-9, 15/50333-1, 19/13465-8, 20/08761-4, 18/11069-5)

CARNEIRO, MARA JUNQUEIRA; PINHEIRO, GUILHERME PEREZ; BASEGGIO, ANDRESSA MARA; MAROSTICA JR, MARIO ROBERTO; SAWAYA, ALEXANDRA CHRISTINE HELENA FRANKLAND. Chemical Composition and Antioxidant Activity of Essential Oil from Male and Female Schinus terebinthifolius. PHARMACOGNOSY RESEARCH, v. 15, n. 3, p. 8-pg., 2023-07-01. (15/13320-9, 16/11524-9, 22/09493-9, 15/50333-1, 19/13465-8, 18/11069-5)