| Full text | |
| Author(s): |
Lorizola, Isabela Micheletti
;
Miyamoto, Josiane Erica
;
Figueiredo Vieira, Ana Luiza
;
Sumere, Beatriz Rocchetti
;
Neves Bezerra, Rosangela Maria
;
Torsoni, Marcio Alberto
;
Torsoni, Adriana Souza
;
Rostagno, Mauricio Ariel
;
Milanski, Marciane
;
Capitani, Caroline Dario
Total Authors: 10
|
| Document type: | Journal article |
| Source: | FOOD CHEMISTRY: MOLECULAR SCIENCES; v. 2, p. 10-pg., 2021-07-30. |
| Abstract | |
Although beet stalks and leaves are not consumed and are usually discarded, they are an important source of bioactive flavonoids possessing antioxidant and anti-inflammatory activity. The aim of this study was to assess the effect of supplementation with beet stalks and leaves on metabolic parameters and glucose homeostasis in mice exposed to a high-fat diet. Six-week-old male Swiss mice were randomly divided into five experimental groups submitted to either standard diet (CT) or high-fat diet (HF), and HF-fed mice were subdivided into three treatment groups supplemented with oven-dehydrated beet stalks and leaves (SL), lyophilized beet stalks and leaves (Ly) or beet stalk and leaf extract (EX). Supplementation with SL promoted a mild improvement in the glucose homeostasis and decreased the protein levels of TNF alpha with no alterations in hepatic triglyceride content. It remains to be clarified if the enhancement in the glucose homeostasis observed in HFSL could be a consequence of improvement in pancreatic insulin secretion and/or glucose uptake from skeletal muscle and white adipose tissues. (AU) | |
| FAPESP's process: | 13/04304-4 - Development of integrated systems for the analysis of bioactive compounds in natural products employing supercritical technology |
| Grantee: | Maurício Ariel Rostagno |
| Support Opportunities: | Research Grants - Young Investigators Grants |
| FAPESP's process: | 13/18498-5 - Effect of beetroot (Beta vulgaris L .) by-products on oxidative stress of high-fat diet rats |
| Grantee: | Isabela Micheletti Lorizola |
| Support Opportunities: | Scholarships in Brazil - Scientific Initiation |
| FAPESP's process: | 16/24768-3 - Evaluation of metabolic parameters of experimental animal models in response to dietary interesterified fat: underlaying molecular mechanisms |
| Grantee: | Josiane Érica Miyamoto |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 15/15035-0 - Metabolic parameters and hepatic gluconeogenesis on hyperlipidemia mice induced by high-fat diet supplemented with beetroot stalks and leaves (beta vulgaris l.) |
| Grantee: | Caroline Dario Capitani |
| Support Opportunities: | Regular Research Grants |