Sustainable extraction methods for the recovery of polyphenolic compounds from grape pomace and its biological properties: a comprehensive review

Author(s)

Castro, Luiz Eduardo Nochi ; Sganzerla, William Gustavo ; Silva, Aline Priscilla Gomes ; John, Oliver Dean ; Barroso, Tiago Linhares Cruz Tabosa ; Rostagno, Mauricio A. ; Forster-Carneiro, Tania

• Document type: Journal article
• Source: PHYTOCHEMISTRY REVIEWS; v. N/A, p. 28-pg., 2024-07-05.

Abstract

Grape pomace (seeds, skin, and stalks) holds promise as a feedstock for various industrial applications. This comprehensive review describes advancements in sustainable and novel extraction processes for recovering polyphenolic compounds and their biological properties. In contrast to traditional methods, sustainable extraction techniques such as microwave-assisted, ultrasound-assisted, pressurized liquid, enzyme-assisted, and hydrothermal processes have been applied to produce high-quality and safe extracts. These methods utilize non-toxic solvents, maintain moderate temperatures, achieve fast extraction times, and require low energy input. The polyphenolic compounds, particularly flavan-3-ols, anthocyanins, and proanthocyanidins extracted from grape pomace, exhibit a wide range of biological properties, including anti-inflammatory, anti-obesity, antioxidant, antidiabetic, hepatoprotective, anticancer, antimicrobial, and heart health-promoting effects. They also contribute to enhancing the gut microbiota population, promoting health. In conclusion, emerging extraction methods offer a sustainable approach to producing bioactive compounds from grape pomace for use in the cosmetic, pharmaceutical, and food industries. (AU)

• FAPESP's process: 19/26925-7 - Development of an automated system for biofuel precursor production using sub-critical technology
• Grantee: William Gustavo Sganzerla
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• FAPESP's process: 18/14938-4 - Waste2energy: integration of supercritical technologies and anaerobic digestion through an automated system for the production of biofuel precursors
• Grantee: Tânia Forster Carneiro
• Support Opportunities: Research Grants - Young Investigators Grants - Phase 2
• FAPESP's process: 21/04096-9 - Integration of the extraction/hydrolysis processes in subcritical water and purification for the valuation of grape bagasse in a biorrefinery concept
• Grantee: Luiz Eduardo Nochi de Castro
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 23/02064-8 - Sustainable bioprocesses for the valorization of cashew apple bagasse (Anacardium occidentale): integration of hydrothermal pretreatment and fermentation processes to produce value-added compounds in a biorefinery concept
• Grantee: Tiago Linhares Cruz Tabosa Barroso
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 18/14582-5 - Development of a two-dimensional extraction, separation and analysis system for evaluating the bioactivity of phytochemicals
• Grantee: Maurício Ariel Rostagno
• Support Opportunities: Research Grants - Young Investigators Grants - Phase 2