Bio-based solvents as a sustainable alternative to develop a multiproduct biorefinery process from archaebacteria Halobacterium salinarum R1

Author(s):Show less -

Kholany, Mariam ; Macario, Ines P. E. ; Veloso, Telma ; Contieri, Leticia S. ; Vaz, Barbara M. C. ; Pereira, Joana L. ; Nunes, Claudia ; Coutinho, Joao A. P. ; Rostagno, Mauricio A. ; Ventura, Sonia P. M. ; Mesquita, Leonardo M. de Souza

• Document type: Journal article
• Source: GREEN CHEMISTRY; v. 26, n. 5, p. 14-pg., 2024-01-30.

Abstract

This study delves into an innovative biorefinery approach to extract multiple high-value compounds from a single biomass source, Halobacterium salinarum R1, a resilient halophilic microorganism. By using bio-based solvents, namely an aqueous solution of gamma-valerolactone (GVL) and ethanol, a simple and efficient pipeline approach was developed, recovering unique pigments, including C-50 bacterioruberin, as well as two additional fractions consisting of protein and polysaccharides. The process is based on sustainable engineering and green chemistry principles, providing a viable alternative to replacing non-renewable solvents. The study addresses environmental concerns by employing bio-based solvents while presenting a cost-effective and sustainable solution. This approach contributes to developing a high-performance and sustainable alternative, promoting the development of a blue bioeconomy. (AU)

• FAPESP's process: 21/11022-1 - Integrated biorefinery of agricultural wastes to obtain natural dyes and value-added bioactive compounds
• Grantee: Leonardo Mendes de Souza Mesquita
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• FAPESP's process: 20/08421-9 - Application of non-volatile alternative solvents to create sustainable two-dimensional and integrated platforms for harnessing agro-industrial waste from jaboticaba and pomegranate fruits
• Grantee: Leonardo Mendes de Souza Mesquita
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 20/03623-2 - Extraction and separation of phenolic compounds from green propolis by a bidimensional system
• Grantee: Letícia Sanches Contieri
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• FAPESP's process: 19/13496-0 - Multi user equipment approved in grant 2018/14582-5: ultra-high pressure liquid chromatography system (UHPLC), composed by a quaternary pump, autoinjector, oven with selection valve and detector (PDA)
• Grantee: Maurício Ariel Rostagno
• Support Opportunities: Multi-user Equipment Program
• FAPESP's process: 21/11023-8 - Development of sustainable methods for propolis extracts by the application of non-volatile alternative solvents
• Grantee: Letícia Sanches Contieri
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate (Direct)
• FAPESP's process: 18/14582-5 - Development of a two-dimensional extraction, separation and analysis system for evaluating the bioactivity of phytochemicals
• Grantee: Maurício Ariel Rostagno
• Support Opportunities: Research Grants - Young Investigators Grants - Phase 2