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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Mass spectrometry in plant metabolomics strategies: from analytical platforms to data acquisition and processing

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Ernst, Madeleine [1] ; Silva, Denise Brentan [1] ; Silva, Ricardo Roberto [2] ; Vencio, Ricardo Z. N. [2] ; Lopes, Norberto Peporine [1]
Total Authors: 5
[1] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Chem & Phys, Nucleo Pesquisa Prod Na & Sintet, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, FFCLRP, Dept Comp & Math, BR-14040901 Ribeirao Preto, SP - Brazil
Total Affiliations: 2
Document type: Review article
Source: NATURAL PRODUCT REPORTS; v. 31, n. 6, p. 784-806, 2014.
Web of Science Citations: 76

Plant metabolomics is a relatively recent research field that has gained increasing interest in the past few years. Up to the present day numerous review articles and guide books on the subject have been published. This review article focuses on the current applications and limitations of the modern mass spectrometry techniques, especially in combination with electrospray ionisation (ESI), an ionisation method which is most commonly applied in metabolomics studies. As a possible alternative to ESI, perspectives on matrix-assisted laser desorption/ionisation mass spectrometry (MALDI-MS) in metabolomics studies are introduced, a method which still is not widespread in the field. In metabolomics studies the results must always be interpreted in the context of the applied sampling procedures as well as data analysis. Different sampling strategies are introduced and the importance of data analysis is illustrated in the example of metabolic network modelling. (AU)

FAPESP's process: 12/18031-7 - Application of MALDI-MS/MS in the vicenin-2 and derivatives analyses: Understanding the ionization processes to production of the images
Grantee:Denise Brentan da Silva
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 09/54098-6 - Acquisition of a mass spectrometer for the generation of images at the Mass Spectrometry Center of the University of São Paulo Ribeirão Preto School of Pharmaceutical Sciences: studies of molecular localization of biologically active substances
Grantee:Norberto Peporine Lopes
Support type: Multi-user Equipment Program
FAPESP's process: 10/14926-4 - Bioinformatics applied to Bioenergy: Probabilistic annotation of cane sugar the metabolome
Grantee:Ricardo Roberto da Silva
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 11/05215-0 - Metabolomics in plant systematics: the arnica model
Grantee:Madeleine Ernst
Support type: Scholarships in Brazil - Master