Formation and properties of hemiesters of carbonic acid in aqueous medium

• Grant number: 17/13137-5
• Support Opportunities: Research Projects - Thematic Grants
• Start date: April 01, 2018
• End date: March 31, 2023
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Claudimir Lucio Do Lago
• Grantee: Claudimir Lucio Do Lago
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Pesquisadores principais: Lucio Angnes
• Associated researchers: Ivano Gebhardt Rolf Gutz ; Lucas Colucci Ducati ; Lucio Angnes ; Rômulo Augusto Ando ; Sandro Roberto Marana
• Associated scholarship(s): 19/22126-2 - Electrochemical behavior of carbonic acid hemiesters in aqueous medium, BP.DR; 18/23768-5 - Carbonic Acid Hemimesters: Nitrogen and Membrane Compounds, BP.PD; 19/01207-4 - Use of CAD and CAM resources for the production of devices of interest in analytical chemistry, BP.TT; 18/20764-9 - Using capillary electrophoresis with capacitively coupled contactless conductivity detection and mass spectrometry, BP.TT; 18/13960-6 - Development of instrumentation for the detection and characterization of hemiesters of carbonic acid, BP.PD

Abstract

Over the last few years, we have studied the Hemiesters of Carbonic Acid (HECAs) spontaneously formed in aqueous medium by reacting HCO3-/CO2 and a compound having at least one hydroxyl group. In a previous FAPESP project (2012/06642-1), we were able to promote a significant improvement in understanding about this class of compounds. In this new phase, we intend to extend the work in several directions: 1) detection and properties of HECAs in cellular membrane; 2) acidity of alkyl carbonic acids; 3) identification of enzymes that catalyze the formation of HECAs; 4) alkanolamines HECAs in industry and biochemistry, and 5) electrochemical behavior of HECAs. The team is diverse and composed of specialists from Theoretical Chemistry to Biochemistry. The aim is to develop analytical techniques and evidence the importance of this class of compounds for industrial and biochemical processes. (AU)

Scientific publications

(44)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GONCALVES, JOSUE M.; DA SILVA, MATHEUS I.; HASHEMINEJAD, MEISAM; TOMA, HENRIQUE E.; ARAKI, KOITI; MARTINS, PAULO R.; ANGNES, LUCIO. Recent Progress in Core@Shell Sulfide Electrode Materials for Advanced Supercapacitor Devices. BATTERIES & SUPERCAPS, MAR 2021. (13/24725-4, 18/21489-1, 18/16896-7, 14/50867-3, 17/13137-5)

SURKOV, ANDREI M.; QUEIROZ, RODRIGO G.; RINCO, RAFAEL S.; RIOS, ALEJANDRO G.; GUTZ, IVANO G. R.; BACCARO, ALEXANDRE L. B.; ANGNES, LUCIO. Graphite-polystyrene composite with enhanced electrochemical and electroanalytical performance. Talanta, v. 223, n. 2, FEB 1 2021. (17/13137-5, 14/50867-3)

NEGAHDARY, MASOUD; ANGNES, LUCIO. lectrochemical nanobiosensors equipped with peptides: a revie. Microchimica Acta, v. 189, n. 3, MAR 2022. (17/13137-5, 14/50867-3, 19/27021-4)

GONCALVES, JOSUE M.; ROCHA, DIEGO P.; SILVA, MURILLO N. T.; MARTINS, PAULO R.; NOSSOL, EDSON; ANGNES, LUCIO; ROUT, CHANDRA SEKHAR; MUNOZ, RODRIGO A. A.. Feasible strategies to promote the sensing performances of spinel MCo2O4 (M = Ni, Fe, Mn, Cu and Zn) based electrochemical sensors: a review. JOURNAL OF MATERIALS CHEMISTRY C, v. 9, n. 25, p. 7852-7887, JUL 7 2021. (17/13137-5, 18/16896-7, 14/50867-3, 20/00325-0)

CERDEIRA FERREIRA, LUIS MARCOS; MARTINS, PAULO ROBERTO; ARAKI, KOITI; ANGNES, LUCIO. Tuning Selectivity and Sensitivity of Mixed-polymeric Tetraruthenated Metalloporphyrins Modified Electrodes as Voltammetric Sensors of Chloramphenicol. Electroanalysis, v. 31, n. 4, p. 688-694, APR 2019. (17/13137-5)

GONCALVES, JOSUE M.; DA SILVA, MATHEUS I.; HASHEMINEJAD, MEISAM; TOMA, HENRIQUE E.; ARAKI, KOITI; MARTINS, PAULO R.; ANGNES, LUCIO. Recent Progress in Core@Shell Sulfide Electrode Materials for Advanced Supercapacitor Devices. BATTERIES & SUPERCAPS, v. 4, n. 9, p. 1397-1427, SEP 2021. (18/21489-1, 18/16896-7, 14/50867-3, 13/24725-4, 17/13137-5)

GONCALVES, JOSUE M.; IGLESIAS, BERNARDO A.; MARTINS, PAULO R.; ANGNES, LUCIO. Recent advances in electroanalytical drug detection by porphyrin/phthalocyanine macrocycles: developments and future perspectives. ANALYST, v. 146, n. 2, p. 365-381, JAN 21 2021. (18/16896-7, 17/13137-5, 14/50867-3)

GONCALVES, JOSUE M.; DE FARIA, LUCAS, V; NASCIMENTO, AMANDA B.; GERMSCHEIDT, RAFAEL L.; PATRA, SANTANU; HERNANDEZ-SARAVIA, LUCAS P.; BONACIN, JULIANO A.; MUNOZ, RODRIGO A. A.; ANGNES, LUCIO. Sensing performances of spinel ferrites MFe2O4 (M = Mg, Ni, Co, Mn, Cu and Zn) based electrochemical sensors: A review. Analytica Chimica Acta, v. 1233, p. 31-pg., 2022-10-22. (13/22127-2, 18/16896-7, 17/13137-5, 20/00325-0, 14/50867-3)

GONCALVES, JOSUE M.; HENNEMANN, ARTUR LUIS; RUIZ-MONTOYA, JOSE G.; MARTINS, PAULO R.; ARAKI, KOITI; ANGNES, LUCIO; SHAHBAZIAN-YASSAR, REZA. Metal-glycerolates and their derivatives as electrode materials: A review on recent developments, challenges, and future perspectives. Coordination Chemistry Reviews, v. 477, p. 29-pg., 2023-02-15. (18/16896-7, 18/21489-1, 17/13137-5, 13/24725-4, 20/06176-7)

NEGAHDARY, MASOUD; AMEKU, WILSON AKIRA; SANTOS, BERLANE GOMES; LIMA, IRLAN DOS SANTOS; DE OLIVEIRA, THAWAN GOMES; FRANCA, MESAQUE CARVALHO; ANGNES, LUCIO. Recent electrochemical sensors and biosensors for toxic agents based on screen-printed electrodes equipped with nanomaterials. Microchemical Journal, v. 185, p. 18-pg., 2023-02-01. (14/50867-3, 19/27021-4, 17/13137-5)

GONCALVES, JOSUE M.; SILVA, MURILLO N. T.; NAIK, KUSHA KUMAR; MARTINS, PAULO R.; ROCHA, DIEGO P.; NOSSOL, EDSON; MUNOZ, RODRIGO A. A.; ANGNES, LUCIO; ROUT, CHANDRA SEKHAR. Multifunctional spinel MnCo₂O₄ based materials for energy storage and conversion: a review on emerging trends, recent developments and future perspectives. JOURNAL OF MATERIALS CHEMISTRY A, v. 9, n. 6, p. 31-pg., 2021-02-16. (18/16896-7, 20/00325-0, 17/13137-5, 14/50867-3)

AZEREDO, NATHALIA F. B.; GONCALVES, JOSUE M.; ROSSINI, PAMELA O.; ARAKI, KOITI; WANG, JOSEPH; ANGNES, LUCIO. Uric acid electrochemical sensing in biofluids based on Ni/Zn hydroxide nanocatalyst. Microchimica Acta, v. 187, n. 7, JUN 9 2020. (14/50867-3, 17/13137-5, 18/21489-1, 18/16896-7)

ROSSINI, PAMELA DE O.; LAZA, ANABEL; AZEREDO, NATHALIA F. B.; GONCALVES, JOSUE M.; FELIX, FABIANA S.; ARAKI, KOITI; ANGNES, LUCIO. Ni-based double hydroxides as electrocatalysts in chemical sensors: A review. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 126, MAY 2020. (18/21489-1, 14/50867-3, 17/13137-5, 18/16896-7)

NEGAHDARY, MASOUD; VELOSO, WILLIAM BARROS; BACIL, RAPHAEL PRATA; BUORO, RAFAEL MARTOS; GUTZ, IVANO GEBHARDT ROLF; PAIXAO, THIAGO REGIS LONGO CESAR; DO LAGO, CLAUDIMIR LUCIO; SAKATA, SOLANGE KAZUMI; MELONI, GABRIEL NEGRAO; FRANCA, MESAQUE CARVALHO; et al. Aptasensing of beta-amyloid (Aβ_(1-42)) by a 3D-printed platform integrated with leaf-shaped gold nanodendrites. SENSORS AND ACTUATORS B-CHEMICAL, v. 393, p. 11-pg., 2023-10-15. (19/27021-4, 17/13137-5, 18/08782-1, 14/50867-3)

GONCALVES, JOSUE M.; MATIAS, TIAGO A.; ANGNES, LUCIO; MARTINS, PAULO R.; ARAKI, KOITI. Review-Tetraruthenated Porphyrins and Composites as Catalysts and Sensor Materials: A Short Review. ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY, v. 9, n. 6, JAN 8 2020. (13/24725-4, 18/16896-7, 17/13137-5, 18/21489-1, 17/50129-0, 14/50867-3)

GONCALVES, JOSUE M.; KUMAR, ABHISHEK; DA SILVA, MATHEUS I.; TOMA, HENRIQUE E.; MARTINS, PAULO R.; ARAKI, KOITI; BERTOTTI, MAURO; ANGNES, LUCIO. Nanoporous Gold-Based Materials for Electrochemical Energy Storage and Conversion. ENERGY TECHNOLOGY, v. 9, n. 5, MAR 2021. (18/16896-7, 17/13137-5, 18/21489-1)

KUMAR, ABHISHEK; GONCALVES, JOSUE M.; LUDER, JOHANN; NAKAMURA, MARCELO; ANGNES, LUCIO; BOUVET, MARCEL; BERTOTTI, MAURO; ARAKI, KOITI. Interplay of hetero-MN4 catalytic sites on graphene for efficient oxygen reduction reaction. Electrochimica Acta, v. 419, p. 12-pg., 2022-07-01. (17/13137-5, 19/14418-3)

AMEKU, WILSON A.; NEGAHDARY, MASOUD; LIMA, IRLAN S.; SANTOS, BERLANE G.; OLIVEIRA, THAWAN G.; PAIXAO, THIAGO R. L. C.; ANGNES, LUCIO. Laser-Scribed Graphene-Based Electrochemical Sensors: A Review. CHEMOSENSORS, v. 10, n. 12, p. 31-pg., 2022-12-01. (18/16896-7, 19/22126-2, 14/50867-3, 17/13137-5)

NEGAHDARY, MASOUD; ANGNES, LUCIO. Recent advances in electrochemical nanomaterial-based aptasensors for the detection of cancer biomarkers. Talanta, v. 259, p. 24-pg., 2023-04-14. (19/27021-4, 17/13137-5, 14/50867-3)

DA COSTA, ERIC TAVARES; OLIVEIRA, DANIEL ROSSADO; DO LAGO, CLAUDIMIR LUCIO. Qualitative and quantitative aspects of time-, charge-, and mobility-based electropherograms. ELECTROPHORESIS, v. 43, n. 23-24, p. 14-pg., 2022-09-03. (18/13960-6, 12/06642-1, 17/13137-5)

NEGAHDARY, MASOUD; BUORO, RAFAEL MARTOS; BACIL, RAPHAEL PRATA; SANTOS, BERLANE GOMES; ANGNES, LUCIO. Design of an electrochemical aptasensor in the presence of an array of gold nanostructure and a GO-MWCNTs nanocomposite: application in diagnosis of Alzheimer's disease. Microchimica Acta, v. 190, n. 10, p. 13-pg., 2023-10-01. (19/27021-4, 17/13137-5, 14/50867-3)

NEGAHDARY, MASOUD; BARROS AZEREDO, NATHALIA FLORENCIA; SANTOS, BERLANE GOMES; DE OLIVEIRA, THAWAN GOMES; DE OLIVEIRA LINS, RENATO SOARES; DOS SANTOS LIMA, IRLAN; ANGNES, LUCIO. Electrochemical Nanomaterial-based Sensors/Biosensors for Drug Monitoring. CURRENT TOPICS IN MEDICINAL CHEMISTRY, v. 23, n. 4, p. 21-pg., 2023-01-01. (19/22126-2, 19/27021-4, 17/13137-5, 14/50867-3)

SHARMA, ABHINAV; ANGNES, LUCIO; SATTARAHMADY, NAGHMEH; NEGAHDARY, MASOUD; HELI, HOSSEIN. Electrochemical Immunosensors Developed for Amyloid-Beta and Tau Proteins, Leading Biomarkers of Alzheimer's Disease. BIOSENSORS-BASEL, v. 13, n. 7, p. 28-pg., 2023-07-01. (19/27021-4, 17/13137-5, 14/50867-3)

SURKOV, ANDREI M.; QUEIROZ, RODRIGO G.; RINCO, RAFAEL S.; RIOS, ALEJANDRO G.; GUTZ, IVANO G. R.; BACCARO, ALEXANDRE L. B.; ANGNES, LUCIO. Graphite-polystyrene composite with enhanced electrochemical and electroanalytical performance. Talanta, v. 223, p. 9-pg., 2021-02-01. (17/13137-5, 14/50867-3)

GONCALVES, JOSUE M.; GHORBANI, ALIREZA; RITTER, TIMOTHY G.; LIMA, IRLAN S.; SARAY, MAHMOUD TAMADONI; PHAKATKAR, ABHIJIT H.; SILVA, VINICIUS D.; PEREIRA, RAFAEL S.; YARIN, ALEXANDER L.; ANGNES, LUCIO; et al. Multimetallic glycerolate as a precursor template of spherical porous high-entropy oxide microparticles. Journal of Colloid and Interface Science, v. 641, p. 10-pg., 2023-03-22. (18/16896-7, 20/06176-7, 17/13137-5, 22/04127-4)

PHAKATKAR, ABHIJIT H.; GONCALVES, JOSUE M.; ZHOU, JIANSHU; RITTER, TIMOTHY G.; SARAY, MAHMOUD TAMADONI; SOROKINA, LIOUDMILA V.; AMIRI, AZADEH; ANGNES, LUCIO; SHOKUHFAR, TOLOU; SHAHBAZIAN-YASSAR, REZA. Enhanced Bacterial Growth by Polyelemental Glycerolate Particles. ACS APPLIED BIO MATERIALS, v. 6, n. 4, p. 10-pg., 2023-03-18. (18/16896-7, 20/06176-7, 17/13137-5)

NEGAHDARY, MASOUD; SHARMA, ABHINAV; ANTHOPOULOS, THOMAS D.; ANGNES, LUCIO. Recent advances in electrochemical nanobiosensors for cardiac biomarkers. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 164, p. 22-pg., 2023-07-01. (19/27021-4, 17/13137-5, 14/50867-3)

CLAUDIMIR LUCIO DO LAGO. A HISTORY OF CARBONIC ACID AND THE CENTRAL ROLE OF BICARBONATE IN THE CO2/H2O SYSTEM. Química Nova, v. 47, n. 8, 2024-05-03. (17/13137-5)

GONCALVES, JOSUE M.; MARTINS, PAULO R.; ROCHA, DIEGO P.; MATIAS, TIAGO A.; JULIAO, MURILO S. S.; MUNOZ, RODRIGO A. A.; ANGNES, LUCIO. Recent trends and perspectives in electrochemical sensors based on MOF-derived materials. JOURNAL OF MATERIALS CHEMISTRY C, v. 9, n. 28, p. 8718-8745, JUL 28 2021. (14/50867-3, 17/13137-5, 18/16896-7, 20/00325-0)

DANIEL, DANIELA; LOPES, FERNANDO SILVA; DO LAGO, CLAUDIMIR LUCIO. A sensitive multiresidue method for the determination of pesticides in marijuana by liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, v. 1603, p. 231-239, OCT 2019. (17/13137-5, 12/06642-1)

GONCALVES, JOSUE M.; LIMA, IRLAN S.; AZEREDO, NATHALIA F. B.; ROCHA, DIEGO P.; DE SIERVO, ABNER; ANGNES, LUCIO. iVCe-Layered Double Hydroxide as Multifunctional Nanomaterials for Energy and Sensor Application. FRONTIERS IN MATERIALS, v. 8, NOV 29 2021. (17/13137-5, 20/00325-0, 07/08244-5, 07/54829-5, 18/16896-7, 14/50867-3)

SANTOS, BERLANE G.; GONCALVES, JOSUE M.; ROCHA, DIEGO P.; HIGINO, GIANE S.; YADAV, THAKUR P.; PEDROTTI, JAIRO J.; AJAYAN, PULICKEL M.; ANGNES, LUCIO. Electrochemical sensor for isoniazid detection by using a WS2/CNTs nanocomposite. SENSORS AND ACTUATORS REPORTS, v. 4, NOV 2022. (19/22126-2, 12/50259-8, 18/16896-7, 17/13137-5, 14/50867-3, 20/00325-0)

ABREU, JULIANA CALDEIRA; MAHR, AMANDA GUIRALDELLI; DO LAGO, CLAUDIMIR LUCIO. Stability-indicating method development for quantification of bromopride, its impurities, and degradation products by ultra-high performance liquid chromatography applying Analytical Quality by Design principles. Journal of Pharmaceutical and Biomedical Analysis, v. 205, OCT 25 2021. (17/13137-5, 12/06642-1)

GONCALVES, JOSUE M.; SILVA, MURILLO N. T.; NAIK, KUSHA KUMAR; MARTINS, PAULO R.; ROCHA, DIEGO P.; NOSSOL, EDSON; MUNOZ, RODRIGO A. A.; ANGNES, LUCIO; ROUT, CHANDRA SEKHAR. Multifunctional spinel MnCo2O4 based materials for energy storage and conversion: a review on emerging trends, recent developments and future perspectives. JOURNAL OF MATERIALS CHEMISTRY A, v. 9, n. 6, p. 3095-3124, FEB 14 2021. (14/50867-3, 20/00325-0, 18/16896-7, 17/13137-5)

GONCALVES, JOSUE M.; DA SILVA, MATHEUS L.; TOMA, HENRIQUE E.; ANGNES, LUCIO; MARTINS, PAULO R.; ARAKI, KOITI. Trimetallic oxides/hydroxides as hybrid supercapacitor electrode materials: a review. JOURNAL OF MATERIALS CHEMISTRY A, v. 8, n. 21, p. 10534-10570, JUN 7 2020. (18/21489-1, 17/13137-5, 18/16896-7)

FELIX, FABIANA S.; BACCARO, ALEXANDRE L. B.; ANGNES, LUCIO. Disposable Voltammetric Immunosensors Integrated with Microfluidic Platforms for Biomedical, Agricultural and Food Analyses: A Review. SENSORS, v. 18, n. 12, DEC 2018. (17/13137-5)

AGUIRRE-ARAQUE, JUAN S.; GONCALVES, JOSUE M.; NAKAMURA, MARCELO; ROSSINI, PAMELA O.; ANGNES, LUCIO; ARAKI, KOITI; TOMA, HENRIQUE E.. GO composite encompassing a tetraruthenated cobalt porphyrin-Ni coordination polymer and its behavior as isoniazid BIA sensor. Electrochimica Acta, v. 300, p. 113-122, MAR 20 2019. (13/24725-4, 17/13137-5)

AZEREDO, NATHALIA F. B.; ROSSINI, PAMELA O.; GONCALVES, JOSUE M.; ASSIS, GEOVANNE L.; ARAKI, KOITI; ANGNES, LUCIO. Nanostructured mixed Ni/Pt hydroxides electrodes for BIA-amperometry determination of hydralazine. Journal of the Taiwan Institute of Chemical Engineers, v. 95, p. 475-480, FEB 2019. (17/13137-5)

NEGAHDARY, MASOUD; ANGNES, LUCIO. Application of electrochemical biosensors for the detection of microRNAs (miRNAs) related to cancer. Coordination Chemistry Reviews, v. 464, p. 26-pg., 2022-08-01. (14/50867-3, 17/13137-5, 19/27021-4)

BALDO, THAISA APARECIDA; PROENCA, CAMILA DOS ANJOS; FELIX, FABIANA DA SILVA; FREITAS, TAYANE AGUIAR; SAKATA, SOLANGE KAZUMI; ANGNES, LUCIO; FARIA, RONALDO CENSI. Disposable electrochemical microfluidic device for ultrasensitive detection of egg allergen in wine samples. Talanta, v. 232, SEP 1 2021. (13/14262-7, 17/24053-7, 16/00991-5, 14/50867-3, 17/13137-5)

OLIVEIRA, THAWAN G.; SANTOS, BERLANE G.; GONCALVES, JOSUE M.; ANGNES, LUCIO. Amperometric detection of indapamide on glassy carbon electrode. Electroanalysis, v. 35, n. 9, p. 9-pg., 2023-05-11. (18/16896-7, 17/13137-5, 14/50867-3)

ATAIDE, VANESSA N.; PRADELA-FILHO, LAURO A.; AMEKU, WILSON A.; NEGAHDARY, MASOUD; OLIVEIRA, THAWAN G.; SANTOS, BERLANE G.; PAIXAO, THIAGO R. L. C.; ANGNES, LUCIO. Paper-based electrochemical biosensors for the diagnosis of viral diseases. Microchimica Acta, v. 190, n. 7, p. 17-pg., 2023-07-01. (19/22126-2, 18/16896-7, 18/08782-1, 14/50867-3, 21/00205-8, 18/14462-0, 17/13137-5)

SANTANA, MICHELE ALVES; LAGO, CLAUDIMIR LUCIO DO. Indirect calibration for capillary electrophoresis with conductivity detection. Analytica Chimica Acta, v. 1158, MAY 8 2021. (12/06642-1, 17/13137-5)

NEGAHDARY, MASOUD; HIRATA, MARIO HIROYUKI; SAKATA, SOLANGE KAZUMI; CICONELLI, ROZANA MESQUITA; BASTOS, GISELE MEDEIROS; BORGES, JESSICA BASSANI; THUROW, HELENA STRELOW; JUNIOR, ALCEU TOTTI SILVEIRA; SAMPAIO, MARCELO FERRAZ; GUIMARAES, LARISSA BERRETTA; et al. Sandwich-like electrochemical aptasensing of heat shock protein 70 kDa (HSP70): Application in diagnosis/prognosis of coronavirus disease 2019 (COVID-19). Analytica Chimica Acta, v. 1242, p. 10-pg., 2023-02-15. (19/27021-4, 17/13137-5, 14/50867-3)