Acute-phase protein behavior in dairy cattle herd naturally infected with Trypanosoma vivax

Author(s)

Sampaio, Paulo Henrique ^[1] ; Fidelis Junior, Otayio Luiz ^[1] ; Marques, Luiz Carlos ^[1] ; Machado, Rosangela Zacarias ^[1] ; Barnabe, Patricia de Athayde ^[2] ; Andre, Marcos Rogerio ^[1] ; Balbuena, Tiago Santana ^[1] ; Cadioli, Fabiano Antonio ^{[1, 3]}

Affiliation

^[1] UNESP Jaboticabal, FCAV, BR-14884900 Jaboticabal, SP - Brazil

^[2] Fundacao Educ Andradina, BR-16901160 Andradina, SP - Brazil

^[3] UNESP Aracatuba, FMVA, BR-16050470 Aracatuba, SP - Brazil

• Document type: Journal article
• Source: Veterinary Parasitology; v. 211, n. 3-4, p. 141-145, JUL 30 2015.
• Web of Science Citations: 2

Abstract

Trypanosoma vivax is a hemoprotozoon that causes disease in cattle and is difficult to diagnose. The host-parasite relationship in cattle that are infected by T. vivax has only been poorly studied. In the present study, a total of 429 serum proteinograms were produced from naturally infected animals (NIF) and were compared with 50 samples from control animals (C). The total protein, IgA band, complement C3 beta chain band, albumin band, antitrypsin band, IgG band, haptoglobin band, complement Cc a chain band and protein HP-20 band presented higher levels in the serum proteinograms of the NIF group. Inter-alphatrypsin inhibitor heavy chain H4, alpha 2-macroglobulin, complement C6, ceruloplasmin, transferrin band and apolipoprotein Al band presented lower levels in this group. There was no significant difference (p < 0.05) in acid glycoprotein serum concentration between the NIF and C groups. Acute phase proteins may be useful for understanding the host-parasite relationship, since the antitrypsin band was only present in the NIF group. This can be used as an indicator for infection in cattle that are naturally infected by T. vivax. (C) 2015 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 11/03302-2 - Serum proteinogram of bovines naturally infected by Trypanosoma vivax
• Grantee: Paulo Henrique Sampaio
• Support type: Scholarships in Brazil - Master
• FAPESP's process: 11/11650-0 - Changes in the protein expression profile of eucalyptus globulus in response to variations in the growth temperature and atmospheric carbon dioxide concentration
• Grantee: Tiago Santana Balbuena
• Support type: Research Grants - Young Investigators Grants
• FAPESP's process: 11/21531-9 - Serum proteinogram and humoral imune response of bovines naturally infected by Trypanosoma vivax
• Grantee: Fabiano Antonio Cadioli
• Support type: Regular Research Grants