Beta-alanine supplementation improves isometric, but not isotonic or isokinetic strength endurance in recreationally strength-trained young men

Author(s):Show less -

Bassinello, Diogo ^[1] ; Painelli, Vitor de Salles ^[1] ; Dolan, Eimear ^[1] ; Lixandrao, Manoel ^[1] ; Cajueiro, Monique ^[1] ; de Capitani, Mariana ^[1] ; Saunders, Bryan ^{[1, 2]} ; Sale, Craig ^[3] ; Artioli, Guilherme G. ^{[1, 2]} ; Gualano, Bruno ^{[1, 2]} ; Roschel, Hamilton ^{[1, 2]}

Affiliation

^[1] Univ Sao Paulo, Fac Med FMUSP, Appl Physiol & Nutr Res Grp, Escola Educ Fis & Esporte, Ave Melo Moraes 65, BR-05508030 Sao Paulo, SP - Brazil

^[2] Univ Sao Paulo, Fac Med FMUSP, Inst Orthopaed & Traumatol, Sao Paulo - Brazil

^[3] Nottingham Trent Univ, Musculoskeletal Physiol Res Grp, Sport Hlth & Performance Enhancement Res Ctr, Sch Sci & Technol, Nottingham - England

• Document type: Journal article
• Source: Amino Acids; v. 51, n. 1, p. 27-37, JAN 2019.
• Web of Science Citations: 2

Abstract

beta-Alanine (BA) supplementation may be ergogenic during high-intensity exercise, primarily due to the buffering of hydrogen cations, although the effects of beta-alanine supplementation on strength endurance are equivocal. The aim of the study was to determine the effects of 4weeks of beta-alanine supplementation on skeletal muscle endurance using a battery of performance tests. This study employed a parallel group, repeated measures, randomised, double-blinded and placebo-controlled design. Twenty recreationally strength-trained healthy males completed tests of isotonic strength endurance (repeated bench and leg press), along with tests of isometric and isokinetic endurance conducted using an isokinetic dynamometer. Tests were performed before and after a 4week intervention, comprising an intake of 6.4gday(-1) of BA (n=9) or placebo (maltodextrin, n=11). Time-to-exhaustion during the isometric endurance test improved by 17% in the BA group (p<0.01), while PL remained unchanged. No significant within-group differences (p>0.1) were shown for any of the performance variables in the isokinetic test (peak torque, fatigue index, total work) nor for the total number of repetitions performed in the isotonic endurance tests (leg or bench press). Four weeks of BA supplementation (6.4gday(-1)) improved isometric, but not isokinetic or isotonic endurance performance. (AU)

• FAPESP's process: 13/14746-4 - Carnosine metabolism in skeletal muscle: a multi-approach study
• Grantee: Bruno Gualano
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 17/04973-4 - Nutritional supplementation and exercise to optimise exercise performance: focus on individual responses and a step towards personalized sports nutrition
• Grantee: Bryan Saunders
• Support Opportunities: Scholarships in Brazil - Young Researchers
• FAPESP's process: 16/50438-0 - Nutritional suplementation and exercise to optimize exercise performance: focus on individual responses and a step towards personalized sports nutrition
• Grantee: Bryan Saunders
• Support Opportunities: Research Grants - Young Investigators Grants
• FAPESP's process: 16/10993-5 - Effects of exercise training in patients undergoing bariatric surgery: a randomized and clinical trial
• Grantee: Hamilton Augusto Roschel da Silva
• Support Opportunities: Regular Research Grants
• FAPESP's process: 15/23072-2 - Effects of b-alanine supplementation on strength performance
• Grantee: Diogo Bassinello Bonoli do Carmo
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 13/04806-0 - Effects of 12 weeks of high-intensity intermittent training on intramuscular carnosine concentrations
• Grantee: Vitor de Salles Painelli
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 15/11328-2 - Carnosine metabolism in skeletal muscle: a multi-approach study. Substudy 3: exploring carnosine role in skeletal muscle
• Grantee: Eimear Bernadette Dolan
• Support Opportunities: Scholarships in Brazil - Post-Doctoral