| Full text | |
| Author(s): |
Alan C. Pilon
;
Denise M. Selegato
;
Richard P. Fernandes
[3]
;
Paula C. P. Bueno
;
Danielle R. Pinho
[5]
;
Fausto Carnevale Neto
[6]
;
Rafael T. Freire
[7]
;
Ian Castro-Gamboa
[8]
;
Vanderlan S. Bolzani
[9]
;
Norberto P. Lopes
[10]
Total Authors: 10
|
| Document type: | Journal article |
| Source: | Química Nova; v. 43, n. 3, p. 329-354, 2020-06-01. |
| Abstract | |
Metabolomics has played a central role in various areas of plant sciences, offering new perspectives for the advancement of agriculture, drug discovery, chemical ecology and taxonomy. Plant metabolomics (identification and quantification) aims to understand the relationship between biological systems and genetic, pathological and or environmental stimuli in terms of differential expression of the metabolism. Owing to the unique challenges, such studies require multidisciplinary skills involving biology, chemistry, statistics, and computer science for the extraction and complete understanding of information. In this sense, this review summarizes the main procedures that involve the steps of plant metabolomic study (design of experiments, sample preparation, analytical methods and data analysis), providing a comprehensive overview, showing the main challenges and limitations and possible solutions for the different approaches used. (AU) | |
| FAPESP's process: | 14/05935-0 - Co-culture of microorganisms isolated from the rhizosphere of Senna spectabilis aiming to produce new bioactive metabolites |
| Grantee: | Denise Medeiros Selegato |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |
| FAPESP's process: | 14/50926-0 - INCT 2014: biodiversity and natural products |
| Grantee: | Vanderlan da Silva Bolzani |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |
| FAPESP's process: | 19/08477-7 - Integrated metabolism analysis for Glycine max responses to water stress |
| Grantee: | Paula Carolina Pires Bueno |
| Support Opportunities: | Scholarships abroad - Research Internship - Post-doctor |
| FAPESP's process: | 17/19702-6 - Integrated omics approaches for the evaluation of the micromolecular phenotypic dynamics of Glycine max (soja) genetically modified for water stress tolerance |
| Grantee: | Paula Carolina Pires Bueno |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 13/07600-3 - CIBFar - Center for Innovation in Biodiversity and Drug Discovery |
| Grantee: | Glaucius Oliva |
| Support Opportunities: | Research Grants - Research, Innovation and Dissemination Centers - RIDC |
| FAPESP's process: | 15/50488-5 - Nordeste: new science for a neglected biome |
| Grantee: | Jonathan James Lloyd |
| Support Opportunities: | Research Projects - SPEC Program |
| FAPESP's process: | 17/17850-8 - Metabolomic analysis of micromolecular diversity of ESI-MS based caatinga |
| Grantee: | Danielle Rocha Pinho |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |
| FAPESP's process: | 14/50265-3 - Distribution and metabolism of natural and synthetic xenobiotics: from the comprehension of reactional process to tissue imaging generation |
| Grantee: | Norberto Peporine Lopes |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |
| FAPESP's process: | 19/15889-0 - Plant traits and natural products databases combined the data mining for the modeling of functions and evolution of secondary metabolites in angiosperms |
| Grantee: | Alan Cesar Pilon |
| Support Opportunities: | Scholarships abroad - Research Internship - Post-doctor |
| FAPESP's process: | 16/13292-8 - Analysis of nitrogen content in antropic influenced areas in Amazon and Atlantic Forest using a metabolomic tools |
| Grantee: | Alan Cesar Pilon |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |