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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

PLANT METABOLOMICS: METHODS AND CHALLENGES

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Author(s):
Alan C. Pilon ; Denise M. Selegato ; Richard P. Fernandes [3] ; Paula C. P. Bueno ; Danielle R. Pinho [5] ; Fausto Carnevale Neto [6] ; Rafael T. Freire [7] ; Ian Castro-Gamboa [8] ; Vanderlan S. Bolzani [9] ; Norberto P. Lopes [10]
Total Authors: 10
Document type: Journal article
Source: Química Nova; v. 43, n. 3, p. 329-354, 2020-06-01.
Abstract

Metabolomics has played a central role in various areas of plant sciences, offering new perspectives for the advancement of agriculture, drug discovery, chemical ecology and taxonomy. Plant metabolomics (identification and quantification) aims to understand the relationship between biological systems and genetic, pathological and or environmental stimuli in terms of differential expression of the metabolism. Owing to the unique challenges, such studies require multidisciplinary skills involving biology, chemistry, statistics, and computer science for the extraction and complete understanding of information. In this sense, this review summarizes the main procedures that involve the steps of plant metabolomic study (design of experiments, sample preparation, analytical methods and data analysis), providing a comprehensive overview, showing the main challenges and limitations and possible solutions for the different approaches used. (AU)

FAPESP's process: 14/50265-3 - Metabolismo e distribuicao de xenobioticos naturais e sinteticos:da compreensao dos processos reacionais a geracao de imagens teciduais.
Grantee:Norberto Peporine Lopes
Support Opportunities: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 19/08477-7 - Integrated metabolism analysis for Glycine max responses to water stress
Grantee:Paula Carolina Pires Bueno
Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
FAPESP's process: 16/13292-8 - Analysis of nitrogen content in antropic influenced areas in Amazon and Atlantic forest using a metabolomic tools.
Grantee:Alan Cesar Pilon
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 15/50488-5 - Nordeste:uma nova ciencia para um importante,porem negligenciado bioma. (fapesp-nerc-biome)
Grantee:Jonathan James Lloyd
Support Opportunities: Research Projects - SPEC Program
FAPESP's process: 13/07600-3 - CIBFar - Center for Research and Innovation in Biodiversity and Drug Discovery
Grantee:Glaucius Oliva
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 19/15889-0 - PLANT TRAITS AND NATURAL PRODUCTS DATABASES COMBINED THE DATA MINING FOR THE MODELING OF FUNCTIONS AND EVOLUTION OF SECONDARY METABOLITES IN ANGIOSPERMS.
Grantee:Alan Cesar Pilon
Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
FAPESP's process: 14/05935-0 - Co-culture of microorganisms isolated from the rhizosphere of Senna spectabilis aiming to produce new bioactive metabolites
Grantee:Denise Medeiros Selegato
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 17/19702-6 - Integrated omics approaches for the evaluation of the micromolecular phenotypic dynamics of Glycine max (soja) genetically modified for water stress tolerance
Grantee:Paula Carolina Pires Bueno
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 17/17850-8 - METABOLOMIC ANALYSIS OF MICROMOLECULAR DIVERSITY OF ESI-MS BASED CAATING
Grantee:Danielle Rocha Pinho
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 14/50926-0 - Inct 2014 - em biodiversidade e produtos naturais.
Grantee:Vanderlan da Silva Bolzani
Support Opportunities: BIOTA-FAPESP Program - Thematic Grants