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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

PLANT METABOLOMICS: METHODS AND CHALLENGES

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Author(s):
Alan C. Pilon ; Denise M. Selegato ; Richard P. Fernandes [3] ; Paula C. P. Bueno ; Danielle R. Pinho [5] ; Fausto Carnevale Neto [6] ; Rafael T. Freire [7] ; Ian Castro-Gamboa [8] ; Vanderlan S. Bolzani [9] ; Norberto P. Lopes [10]
Total Authors: 10
Document type: Journal article
Source: Química Nova; v. 43, n. 3, p. 329-354, 2020-06-01.
Abstract

Metabolomics has played a central role in various areas of plant sciences, offering new perspectives for the advancement of agriculture, drug discovery, chemical ecology and taxonomy. Plant metabolomics (identification and quantification) aims to understand the relationship between biological systems and genetic, pathological and or environmental stimuli in terms of differential expression of the metabolism. Owing to the unique challenges, such studies require multidisciplinary skills involving biology, chemistry, statistics, and computer science for the extraction and complete understanding of information. In this sense, this review summarizes the main procedures that involve the steps of plant metabolomic study (design of experiments, sample preparation, analytical methods and data analysis), providing a comprehensive overview, showing the main challenges and limitations and possible solutions for the different approaches used. (AU)

FAPESP's process: 16/13292-8 - Analysis of nitrogen content in antropic influenced areas in Amazon and Atlantic Forest using a metabolomic tools
Grantee:Alan Cesar Pilon
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 17/17850-8 - Metabolomic analysis of micromolecular diversity of ESI-MS based caatinga
Grantee:Danielle Rocha Pinho
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 19/15889-0 - Plant traits and natural products databases combined the data mining for the modeling of functions and evolution of secondary metabolites in angiosperms
Grantee:Alan Cesar Pilon
Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
FAPESP's process: 14/50265-3 - Distribution and metabolism of natural and synthetic xenobiotics: from the comprehension of reactional process to tissue imaging generation
Grantee:Norberto Peporine Lopes
Support Opportunities: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 15/50488-5 - Nordeste: new science for a neglected biome
Grantee:Jonathan James Lloyd
Support Opportunities: Research Projects - SPEC Program
FAPESP's process: 17/19702-6 - Integrated omics approaches for the evaluation of the micromolecular phenotypic dynamics of Glycine max (soja) genetically modified for water stress tolerance
Grantee:Paula Carolina Pires Bueno
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 19/08477-7 - Integrated metabolism analysis for Glycine max responses to water stress
Grantee:Paula Carolina Pires Bueno
Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
FAPESP's process: 14/50926-0 - INCT 2014: biodiversity and natural products
Grantee:Vanderlan da Silva Bolzani
Support Opportunities: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 14/05935-0 - Co-culture of microorganisms isolated from the rhizosphere of Senna spectabilis aiming to produce new bioactive metabolites
Grantee:Denise Medeiros Selegato
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 13/07600-3 - CIBFar - Center for Innovation in Biodiversity and Drug Discovery
Grantee:Glaucius Oliva
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC