Cello-oligosaccharides production from lignocellulosic biomass and their emerging prebiotic applications

Author(s)

Avila, Patricia F. ^[1] ; Silva, Marcos F. ^[1] ; Martins, Manoela ^[1] ; Goldbeck, Rosana ^[1]

Affiliation

^[1] Univ Estadual Campinas, UNICAMP, Sch Food Engn, Lab Bioproc & Metab Engn, 80, Cidade Univ, BR-13083862 Campinas, SP - Brazil

• Document type: Review article
• Source: WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY; v. 37, n. 5 MAY 2021.
• Web of Science Citations: 1

Abstract

Cello-oligosaccharides (COS) are linear oligosaccharides composed of beta-1,4-linked glucopyranose units. They comprise a group of important new oligosaccharides of significant interest and potential applications in the pharmaceutical, food, chemical, and feed industries, currently emerging as potential prebiotic compounds. COS from lignocellulosic biomass, specifically the agro-industrial residues and by-products of the forestry industry, constitute a new attractive process that imposes the sustainable use of biomass resources. Two main strategies have been used for the production of COS: acid-based and enzyme-based cellulose hydrolysis. The latter has been considered more attractive due to the use of milder reaction conditions and less production of monomers. This review summarizes that although COS is emerging as a potential prebiotic with also other potential applications, there is a lack of information regarding the large-scale production, which could be associated with the recalcitrant nature of cellulose compared to other polysaccharides, which hinders the hydrolysis of its dense network. {[}GRAPHICS] . (AU)

• FAPESP's process: 19/08542-3 - Enzymatic biotechnology for the xylo-oligosaccharides production from lignocellulosic agroindustrial residues aimed the production of symbiotics
• Grantee: Rosana Goldbeck Coelho
• Support Opportunities: Regular Research Grants
• FAPESP's process: 15/20630-4 - Biorefinery development integrated to a bioethanol sugar cane plant with zero CO2 emission: routes to convert renewable resources to bio-products and bio-electricity
• Grantee: Rubens Maciel Filho
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 15/50612-8 - An integrated approach to explore a novel paradigm for biofuel production from lignocellulosic feedstocks
• Grantee: Telma Teixeira Franco
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 17/24503-2 - Use of agroindustrial lignocellulosic waste for the production of oligosaccharides aiming at obtaining a prebiotic agent in human health
• Grantee: Patricia Felix Avila
• Support Opportunities: Scholarships in Brazil - Doctorate