| Full text | |
| Author(s): |
Perim, Pedro
;
Gobbi, Nathan
;
Duarte, Breno
;
Farias de Oliveira, Luana
;
Costa, Luiz Augusto Riani
;
Sale, Craig
;
Gualano, Bruno
;
Dolan, Eimear
;
Saunders, Bryan
Total Authors: 9
|
| Document type: | Journal article |
| Source: | European Journal of Sport Science; v. 22, n. 8, p. 10-pg., 2021-06-16. |
| Abstract | |
This study investigated the effect of beta-alanine supplementation on short-duration sprints and final 4-km simulated uphill cycling time-trial performance during a comprehensive and novel exercise protocol representative of the demands of road-race cycling, and determined if changes were related to increases in muscle carnosine content. Seventeen cyclists (age 38 +/- 9 y, height 1.76 +/- 0.07 m, body mass 71.4 +/- 8.8 kg, V?O-2max 52.4 +/- 8.3 ml center dot kg(-1)center dot min(-1)) participated in this placebo-controlled, double-blind study. Cyclists undertook a prolonged intermittent cycling protocol lasting 125 min, with a 10-s sprint every 20 min, finishing with a 4-km time-trial at 5% simulated incline. Participants completed two familiarization sessions, and two main sessions, one pre-supplementation and one post-supplementation following 28 days of 6.4 g center dot day(-1) of beta-alanine (N=11) or placebo (N=6; maltodextrin). Muscle biopsies obtained pre- and post-supplementation were analysed for muscle carnosine content. There were no main effects on sprint performance throughout the intermittent cycling test (all P>0.05). There was no group (P=0.69), time (P=0.50) or group x time interaction (P=0.26) on time-to-complete the 4-km time-trial. Time-to-completion did not change from pre- to post-supplementation for BA (-19.2 +/- 45.6 s, P=0.43) or PL (+2.8 +/- 31.6 s, P=0.99). Beta-alanine supplementation increased muscle carnosine content from pre- to post-supplementation (+9.4 +/- 4.0 mmol center dot kg(-1)dm; P<0.0001) but was not related to performance changes (r=0.320, P=0.37). Chronic beta-alanine supplementation increased muscle carnosine content but did not improve short-duration sprint performance throughout simulated road race cycling, nor 4-km uphill time-trial performance conducted at the end of this cycling test. (AU) | |
| FAPESP's process: | 16/50438-0 - Nutritional suplementation and exercise to optimize exercise performance: focus on individual responses and a step towards personalized sports nutrition |
| Grantee: | Bryan Saunders |
| Support Opportunities: | Research Grants - Young Investigators Grants |
| FAPESP's process: | 19/07497-4 - Effects of different types of carbohydrates during exercise on performance and metabolic responses |
| Grantee: | Nathan Gobbi de Oliveira |
| Support Opportunities: | Scholarships in Brazil - Master |
| FAPESP's process: | 19/05616-6 - The bone response to exercise: a translational research program exploring clinical and mechanistic aspects |
| Grantee: | Eimear Bernadette Dolan |
| Support Opportunities: | Research Grants - Young Investigators Grants |
| FAPESP's process: | 19/06140-5 - Acute effects of b-alanine intake on regulatory mechanisms of muscle carnosine content |
| Grantee: | Breno Duarte Costa |
| Support Opportunities: | Scholarships in Brazil - Master |
| FAPESP's process: | 18/01594-5 - Blood and muscle responses to sodium bicarbonate supplementation and subsequent exercise performance |
| Grantee: | Pedro Henrique Lopes Perim |
| Support Opportunities: | Scholarships in Brazil - Master |
| FAPESP's process: | 17/13552-2 - Reducing sedentary time in clinical populations: the take a stand for health study |
| Grantee: | Bruno Gualano |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 16/17391-0 - Carnosine metabolism in skeletal muscle: a multi-approach study |
| Grantee: | Pedro Henrique Lopes Perim |
| Support Opportunities: | Scholarships in Brazil - Scientific Initiation |