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From seeds to final products: feasible manufacturing routes of annatto applying process intensification and process integration

Abstract

Perspectives and future trends about production processes are indicating new strategies for reducing expenses (energetic, time, reprocess, etc.) without affecting the products quality. Based on this scenario, the current project covers a research that focuses on applying the principles of process intensification and process integration to the whole use of annatto seeds as a source of bioactive compounds. We will study feasible routes for manufacturing annatto seeds through the use of supercritical technology and low-pressure technologies. The objective is to obtain fractionated extracts containing tocotrienols and geranylgeraniol, which could be applied in edible coatings and products with functional properties in the food, chemical and pharmaceutical fields. Coproducts from high-pressure processes will be used for obtaining other value-added products, as modified starch, oligosaccharides and the carotenoid bixin. This carotenoid is a coloring agent and presents antioxidant properties. Processes on encapsulation and particle formation will be applied to maintain the bioactive compounds stability. The more suitable manufacturing routes, based on experimental and simulated information, will be chosen. Thus, this project is intended to contribute with forthcoming useful information, both technic and economic data, aiming at overcoming the existing drawbacks for establishing small biorefineries of very promising raw materials and also enabling the creation of industrial opportunities. (AU)

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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (25)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
TORRES, R. ABEL C.; SANTANA, ADINA L.; SANTOS, DIEGO T.; ALBARELLI, JULIANA Q.; MEIRELES, M. ANGELA A. A novel process for CO2 purification and recycling based on subcritical adsorption in oat bran. JOURNAL OF CO2 UTILIZATION, v. 34, p. 362-374, DEC 2019. Web of Science Citations: 0.
SANTANA, ADINA L.; SANTOS, DIEGO T.; MEIRELES, M. ANGELA A. Perspectives on small-scale integrated biorefineries using supercritical CO2 as a green solvent. CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY, v. 18, p. 1-12, AUG 2019. Web of Science Citations: 3.
ZABOT, GIOVANI L.; SILVA, ERIC KEVEN; EMERICK, LUCAS B.; FELISBERTO, MARIA HERMINIA F.; SILVA CLERICI, MARIA TERESA P.; MEIRELES, M. ANGELA A. Physicochemical, morphological, thermal and pasting properties of a novel native starch obtained from annatto seeds. FOOD HYDROCOLLOIDS, v. 89, p. 321-329, APR 2019. Web of Science Citations: 3.
HATAMI, TAHMASB; JOHNER, JULIO C. F.; ZABOT, GIOVANI L.; MEIRELES, M. ANGELA A. Supercritical fluid extraction assisted by cold pressing from clove buds: Extraction performance, volatile oil composition, and economic evaluation. JOURNAL OF SUPERCRITICAL FLUIDS, v. 144, p. 39-47, FEB 2019. Web of Science Citations: 4.
ALBARELLI, JULIANA Q.; SANTOS, DIEGO T.; ENSINAS, ADRIANO V.; MARECHAL, FRANCOIS; COCERO, MARIA J.; MEIRELES, M. ANGELA A. Product diversification in the sugarcane biorefinery through algae growth and supercritical CO2 extraction: Thermal and economic analysis. RENEWABLE ENERGY, v. 129, n. B, SI, p. 776-785, DEC 2018. Web of Science Citations: 4.
ALBARELLI, JULIANA Q.; SANTOS, DIEGO T.; MEIRELES, M. ANGELA A. Thermo-economic evaluation of a new approach to extract sugarcane wax integrated to a first and second generation biorefinery. BIOMASS & BIOENERGY, v. 119, p. 69-74, DEC 2018. Web of Science Citations: 0.
NATHIA-NEVES, GRAZIELLE; NOGUEIRA, GISLAINE CHYSTINA; VARDANEGA, RENATA; DE ALMEIDA MEIRELES, MARIA ANGELA. Identification and quantification of genipin and geniposide from Genipa americana L. by HPLC-DAD using a fused-core column. FOOD SCIENCE AND TECHNOLOGY, v. 38, n. 1, p. 116-122, DEC 2018. Web of Science Citations: 0.
ALBARELLI, JULIANA Q.; SANTOS, DIEGO T.; ENSINAS, V, ADRIANO; MARECHAL, FRANCOIS; COCERO, MARIA J.; MEIRELES, M. ANGELA A. Comparison of extraction techniques for product diversification in a supercritical water gasification-based sugarcane-wet microalgae biorefinery: Thermoeconomic and environmental analysis. JOURNAL OF CLEANER PRODUCTION, v. 201, p. 697-705, NOV 10 2018. Web of Science Citations: 3.
JOHNER, JULIO C. F.; HATAMI, TAHMASB; ZABOT, GIOVANI L.; MEIRELES, M. ANGELA A. Kinetic behavior and economic evaluation of supercritical fluid extraction of oil from pequi (Caryocar brasiliense) for various grinding times and solvent flow rates. JOURNAL OF SUPERCRITICAL FLUIDS, v. 140, p. 188-195, OCT 2018. Web of Science Citations: 3.
JOHNER, JULIO C. F.; HATAMI, TAHMASB; MEIRELES, M. ANGELA A. Developing a supercritical fluid extraction method assisted by cold pressing for extraction of pequi (Caryocar brasiliense). JOURNAL OF SUPERCRITICAL FLUIDS, v. 137, p. 34-39, JUL 2018. Web of Science Citations: 6.
CARVALHO, PEDRO I. N.; OSORIO-TOBON, JUAN F.; ZABOT, GIOVANI L.; MEIRELES, M. ANGELA A. Spatial and temporal temperature distributions in fixed beds undergoing supercritical fluid extraction. INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES, v. 47, p. 504-516, JUN 2018. Web of Science Citations: 0.
JULIANA Q. ALBARELLI; DIEGO T. SANTOS; MARÍA JOSÉ COCERO; MARIA ANGELA. A. MEIRELES. Perspectives on the integration of a supercritical fluid extraction plant to a sugarcane biorefinery: thermo-economical evaluation of CO2 recycle systems. FOOD SCIENCE AND TECHNOLOGY, v. 38, n. 1, p. -, Mar. 2018.
ALBARELLI, JULIANA Q.; SANTOS, DIEGO T.; COCERO, MARIA JOSE; MEIRELES, MARIA ANGELA A. Perspectives on the integration of a supercritical fluid extraction plant to a sugarcane biorefinery: thermo-economical evaluation of CO2 recycle systems. FOOD SCIENCE AND TECHNOLOGY, v. 38, n. 1, p. 13-18, JAN-MAR 2018. Web of Science Citations: 1.
SANTANA, ADINA L.; ALBARELLI, JULIANA Q.; SANTOS, DIEGO T.; SOUZA, RENATO; MACHADO, NELIO T.; ARAUJO, MARILENA E.; MEIRELES, M. ANGELA A. Kinetic behavior, mathematical modeling, and economic evaluation of extracts obtained by supercritical fluid extraction from defatted assai waste. FOOD AND BIOPRODUCTS PROCESSING, v. 107, p. 25-35, JAN 2018. Web of Science Citations: 4.
GRAZIELLE NÁTHIA-NEVES; GISLAINE CHYSTINA NOGUEIRA; RENATA VARDANEGA; MARIA ANGELA DE ALMEIDA MEIRELES. Identification and quantification of genipin and geniposide from Genipa americana L. by HPLC-DAD using a fused-core column. FOOD SCIENCE AND TECHNOLOGY, v. 38, p. 116-122, Dez. 2018.
ALBARELLI, JULIANA Q.; SANTOS, DIEGO T.; ENSINAS, ADRIANO V.; MARECHAL, FRANCOIS; MATO, FIDEL A.; COCERO, MARIA J.; MEIRELES, M. ANGELA A. Thermo-economic and environmental comparison of supercritical water and enzymatic hydrolysis of sugarcane bagasse in a biorefinery concept. ENERGY, v. 141, p. 139-148, DEC 15 2017. Web of Science Citations: 3.
VARDANEGA, RENATA; DALMOLIN, IREDE A.; NOGUEIRA, GISLAINE C.; HATAMI, TAHMASB; MEIRELES, M. ANGELA A. Phase behaviour and mathematical modelling for the system annatto seed oil in compressed carbon dioxide plus ethanol as co-solvent. JOURNAL OF SUPERCRITICAL FLUIDS, v. 130, p. 56-62, DEC 2017. Web of Science Citations: 3.
ZABOT, GIOVANI L.; BITENCOURTE, IURI P.; TRES, MARCUS V.; MEIRELES, M. A. A. Process intensification for producing powdered extracts rich in bioactive compounds: An economic approach. JOURNAL OF SUPERCRITICAL FLUIDS, v. 119, p. 261-273, JAN 2017. Web of Science Citations: 8.
SILVA, ERIC KEVEN; ZABOT, GIOVANI L.; BARGAS, MATHEUS A.; MEIRELES, M. ANGELA A. Microencapsulation of lipophilic bioactive compounds using prebiotic carbohydrates: Effect of the degree of inulin polymerization. Carbohydrate Polymers, v. 152, p. 775-783, NOV 5 2016. Web of Science Citations: 17.
ZABOT, GIOVANI L.; SILVA, ERIC KEVEN; AZEVEDO, VIVIANE M.; MEIRELES, M. ANGELA A. Replacing modified starch by inulin as prebiotic encapsulant matrix of lipophilic bioactive compounds. Food Research International, v. 85, p. 26-35, JUL 2016. Web of Science Citations: 15.
SILVA, ERIC KEVEN; ZABOT, GIOVANI L.; CAZARIN, CINTHIA B. B.; MAROSTICA, JR., MARIO R.; MEIRELES, M. ANGELA A. Biopolymer-prebiotic carbohydrate blends and their effects on the retention of bioactive compounds and maintenance of antioxidant activity. Carbohydrate Polymers, v. 144, p. 149-158, JUN 25 2016. Web of Science Citations: 19.
ALBARELLI, JULIANA Q.; SANTOS, DIEGO T.; JOSE COCERO, MARIA; MEIRELES, M. ANGELA A. Economic Analysis of an Integrated Annatto Seeds-Sugarcane Biorefinery Using Supercritical CO2 Extraction as a First Step. MATERIALS, v. 9, n. 6 JUN 2016. Web of Science Citations: 9.
ZABOT, GIOVANI L.; MEIRELES, M. ANGELA A. On-line process for pressurized ethanol extraction of onion peels extract and particle formation using supercritical antisolvent. JOURNAL OF SUPERCRITICAL FLUIDS, v. 110, p. 230-239, APR 2016. Web of Science Citations: 16.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.
Filed patent(s) as a result of this research project

Solicitação em análise e dentro do prazo legal de sigilo previsto na legislação BR1320180732411 - Universidade Estadual de Campinas (UNICAMP) . Solicitação em análise e dentro do prazo legal de sigilo previsto na legislação - November 2018, 12