Determination of antioxidant potential, in vitro bioaccessibility and evaluation of antidiabetic and prebiotic activities from the uvaia (Eugenia pyriformis Cambess)

• Grant number: 20/00225-6
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): August 01, 2020
• Effective date (End): July 31, 2024
• Field of knowledge: Agronomical Sciences - Food Science and Technology - Food Science
• Principal Investigator: Glaucia Maria Pastore
• Grantee: David de Paulo Farias
• Host Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated scholarship(s): 22/05242-1 - Effect of colonic fermentation on the antidiabetic potential of uvaia (Eugenia pyriformis Cambess.), BE.EP.DR

Abstract

Noncommunicable Chronic Diseases (NCDs) are today a global concern due to economic and public health losses worldwide. Among the NCDs, diabetes mellitus stands out mainly for the high mortality rates, besides to the social and economic repercussions. Within this context, there is a growing demand for foods that can bring health benefits, as much scientific evidence has shown that adopting a healthy diet reduces the risk of developing NCDs, whose etiology is often related to nutritional and metabolic disorders. In addition, vegetable consumption is highly recommended because these foods, besides nourishing, can provide important bioactive compounds for maintaining redox status in the human body, reducing the incidence of NCDs such as type 2 diabetes. Brazil is a country rich in native fruit species with excellent nutritional and therapeutic characteristics. The uvaia (Eugenia pyriformis Cambess) is a native fruit species of the Atlantic Rainforest that, besides presenting excellent nutritional value, has high content of bioactive compounds such as phenolic. However, little information is available in the literature about its functional potential and biological properties. Thus, this project proposes to evaluate the antioxidant capacity and antidiabetic and prebiotic potential of extracts of edible fraction (pulp + peel) and seed from the uvaia, in order to know their biological effects and provide subsidies for future research aimed at elucidating the physiological and molecular mechanisms for the prevention of NCDs. (AU)

Scientific publications

(8)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ARAUJO, NAYARA MACEDO PEIXOTO; ARRUDA, HENRIQUE SILVANO; FARIAS, DAVID DE PAULO; MOLINA, GUSTAVO; PEREIRA, GUSTAVO ARAUJO; PASTORE, GLAUCIA MARIA. Plants from the genus Eugenia as promising therapeutic agents for the management of diabetes mellitus: A review. Food Research International, v. 142, APR 2021. (20/00225-6, 18/10608-0, 15/50333-1)

DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; DIAS-AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; DE SOUZA, FLORISVALDO GAMA; CATHARINO, RODRIGO RAMOS; DO SACRAMENTO, CELIO KERSUL; PASTORE, GLAUCIA MARIA. Gastrointestinal bioaccessibility and bioactivity of phenolic compounds from araca-boi fruit. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 135, JAN 2021. (20/00225-6, 19/05718-3)

DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; DIAS-AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; DE SOUZA, FLORISVALDO GAMA; CATHARINO, RODRIGO RAMOS; DO SACRAMENTO, CELIO KERSUL; PASTORE, GLAUCIA MARIA. Chemical characterization of Eugenia stipitata: A native fruit from the Amazon rich in nutrients and source of bioactive compounds. Food Research International, v. 139, JAN 2021. (20/00225-6, 15/50333-1, 19/05718-3)

DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; PASTORE, GLAUCIA MARIA. Underutilized plants of the Cactaceae family: Nutritional aspects and technological applications. Food Chemistry, v. 362, NOV 15 2021. (15/50333-1, 20/00225-6)

DE SOUZA, FLORISVALDO GAMA; DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; ZANOTTO, ALINE WASEM; NERI-NUMA, IRAMAIA ANGELICA; PASTORE, GLAUCIA MARIA. Brazilian fruits of Arecaceae family: An overview of some representatives with promising food, therapeutic and industrial applications. Food Research International, v. 138, p. 14-pg., 2020-12-01. (15/50333-1, 20/00225-6)

DE SOUZA, FLORISVALDO GAMA; DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; ZANOTTO, ALINE WASEM; NERI-NUMA, IRAMAIA ANGELICA; PASTORE, GLAUCIA MARIA. Brazilian fruits of Arecaceae family: An overview of some representatives with promising food, therapeutic and industrial applications. Food Research International, v. 138, n. A, DEC 2020. (15/50333-1, 20/00225-6)

FARIAS, DAVID DE PAULO; DE ARAUJO, FABIO FERNANDES; NERI-NUMA, IRAMAIA ANGELICA; DIAS-AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; CATHARINO, RODRIGO RAMOS; PASTORE, GLAUCIA MARIA. Effect of in vitro digestion on the bioaccessibility and bioactivity of phenolic compounds in fractions of Eugenia pyriformis fruit. Food Research International, v. 150, n. A, DEC 2021. (20/00225-6, 19/05718-3, 20/15163-6, 15/50333-1)

DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; DIAS-AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; DE SOUZA, FLORISVALDO GAMA; CATHARINO, RODRIGO RAMOS; DO SACRAMENTO, CELIO KERSUL; PASTORE, GLAUCIA MARIA. Influence of high-intensity ultrasound on color, chemical composition and antioxidant properties of araca-boi pulp. Food Chemistry, v. 338, FEB 15 2021. (20/00225-6, 15/50333-1, 19/05718-3)