Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Phenolic Isomers from Plantago catharinea Leaves: Isolation, Identification, Quantification and in vitro Antioxidant Activity

Author(s):
de Souza Mesquita, Leonardo Mendes ; da Rocha, Claudia Quintino ; Lima Affonso, Luiz Henrique ; Cerulli, Antonietta ; Piacente, Sonia ; Pereira Tangerina, Marcelo Marucci ; Goncalves Martins, Maria Bernadete ; Vilegas, Wagner
Total Authors: 8
Document type: Journal article
Source: NATURAL PRODUCT COMMUNICATIONS; v. 12, n. 3, p. 409-412, MAR 2017.
Web of Science Citations: 1
Abstract

In this study we isolated two polyphenolic acids of m/z 639, called catharinol A and catharinol B, from Plantago catharinea L. (Plantaginaceae) leaves. Although presenting very similar structures, catharinol A showed higher antioxidant activity when compared with gallic acid and quercetin standards. These compounds are position isomers and present in their chemical structure the rare sugar D-allose. Molecules with similar constitution are known to have important biological activities such as antitumor and immunosuppressive. These compounds were isolated by high-performance liquid chromatography (HPLC) and characterized by mass spectrometry (FIA-ESI-IT-MS/MS) and nuclear magnetic resonance (NMR). This work is the first study on the chemical composition of P. catharinea and encourages the production of Plantago species as a good source of bioactive molecules. (AU)

FAPESP's process: 13/07681-3 - Isolation and identification of secondary metabolites from Plantago catharinea (Plantaginaceaee) leaves
Grantee:Leonardo Mendes de Souza Mesquita
Support type: Scholarships abroad - Research Internship - Scientific Initiation
FAPESP's process: 09/52237-9 - Standardized herbal medicines for the treatment of chronic diseases
Grantee:Wagner Vilegas
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 11/23113-0 - Plantago Secretory Structures: structural morphology and chemical - a leaf compared study
Grantee:Leonardo Mendes de Souza Mesquita
Support type: Scholarships in Brazil - Scientific Initiation