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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Phenolic Isomers from Plantago catharinea Leaves: Isolation, Identification, Quantification and in vitro Antioxidant Activity

de Souza Mesquita, Leonardo Mendes ; da Rocha, Claudia Quintino ; Lima Affonso, Luiz Henrique ; Cerulli, Antonietta ; Piacente, Sonia ; Pereira Tangerina, Marcelo Marucci ; Goncalves Martins, Maria Bernadete ; Vilegas, Wagner
Total Authors: 8
Document type: Journal article
Source: NATURAL PRODUCT COMMUNICATIONS; v. 12, n. 3, p. 409-412, MAR 2017.
Web of Science Citations: 1

In this study we isolated two polyphenolic acids of m/z 639, called catharinol A and catharinol B, from Plantago catharinea L. (Plantaginaceae) leaves. Although presenting very similar structures, catharinol A showed higher antioxidant activity when compared with gallic acid and quercetin standards. These compounds are position isomers and present in their chemical structure the rare sugar D-allose. Molecules with similar constitution are known to have important biological activities such as antitumor and immunosuppressive. These compounds were isolated by high-performance liquid chromatography (HPLC) and characterized by mass spectrometry (FIA-ESI-IT-MS/MS) and nuclear magnetic resonance (NMR). This work is the first study on the chemical composition of P. catharinea and encourages the production of Plantago species as a good source of bioactive molecules. (AU)

FAPESP's process: 13/07681-3 - Isolation and identification of secondary metabolites from Plantago catharinea (Plantaginaceaee) leaves
Grantee:Leonardo Mendes de Souza Mesquita
Support type: Scholarships abroad - Research Internship - Scientific Initiation
FAPESP's process: 09/52237-9 - Standardized herbal medicines for the treatment of chronic diseases
Grantee:Wagner Vilegas
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 11/23113-0 - Plantago Secretory Structures: structural morphology and chemical - a leaf compared study
Grantee:Leonardo Mendes de Souza Mesquita
Support type: Scholarships in Brazil - Scientific Initiation