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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Benzimidazoles in wastewater: Analytical method development, monitoring and degradation by photolysis and ozonation

Full text
Author(s):
Porto, Rafael Silveira [1] ; Rodrigues-Silva, Caio [1] ; Schneider, Jerusa [2] ; Rath, Susanne [1]
Total Authors: 4
Affiliation:
[1] Univ Estadual Campinas, Dept Analyt Chem, Inst Chem, POB 6154, BR-13084971 Campinas, SP - Brazil
[2] Univ Estadual Campinas, Sch Civil Engn Architecture & Urban Design, POB 6143, BR-13083889 Campinas, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Journal of Environmental Management; v. 232, p. 729-737, FEB 15 2019.
Web of Science Citations: 1
Abstract

Pharmaceutical residues are constantly released into natural waters, mainly from wastewater treatment plants (WWTPs) whose processes are unable to completely eliminate them. Among these drugs, the occurrence of benzimidazoles, a class of antiparasitics for human and veterinary use, has been reported in WWTP effluents and surface waters. In this study, an SPE-UHPLC-MS/MS method was developed and optimized for extraction and quantitation of benzimidazoles in influents and effluents of a local WWTP and in hospital wastewater. The extraction procedure was optimized using response surface methodology (Box-Behnken design) and the optimal parameters were as follows: 2.0 mL of loading solvent consisting of a mixture of water:methanol (95:5, v/v) and temperature at 43 degrees C. In hospital wastewater, albendazole (ABZ) and its principal metabolite ricobendazole (RBZ) were the main benzimidazole-related contaminants and were found at concentrations of up to 3810 and 3894 ng L-1, respectively. The WWTP system was able to remove from 46% to 95% of the ABZ quantified in the influent, discharging an effluent with 16-441 ng L-1 of ABZ. The concentrations of other benzimidazoles and metabolites in the WWTP effluents remained below 350 ng L-1. WWTP effluents fortified with 50 mu g L-1 of ABZ required 26.7 mg(o3) L-1 to remove ABZ and RBZ. After ozonation, the COD and BOD5 of the effluents were reduced by 27%. Photolysis by UVA radiation was not effective to remove ABZ and FBZ from the effluent samples. (AU)

FAPESP's process: 13/09543-7 - Residues of veterinary drugs in the environment
Grantee:Susanne Rath
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 14/16622-3 - Identification of intermediates formed during degradation of veterinary drugs by advanced oxidation processes
Grantee:Caio Alexandre Augusto Rodrigues da Silva
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 14/50951-4 - INCT 2014: Advanced Analytical Technologies
Grantee:Celio Pasquini
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 18/03571-2 - Pharmaceuticals in the Aquatic Environment.
Grantee:Susanne Rath
Support Opportunities: Regular Research Grants