| Full text | |
| Author(s): |
Camargo, Jessica R.
[1]
;
Andreotti, Isabella A. A.
[1, 2]
;
Kalinke, Cristiane
[3]
;
Henrique, Julia M.
[1]
;
Bonacin, Juliano A.
[3]
;
Janegitz, Bruno C.
[1]
Total Authors: 6
|
| Affiliation: | [1] Univ Fed Sao Carlos, Dept Ciencias Nat Matemat & Educ, BR-13600970 Araras, SP - Brazil
[2] Univ Fed Sao Carlos, Ctr Ciencias Exatas & Tecnol, BR-13565905 Sao Carlos, SP - Brazil
[3] Univ Estadual Campinas, Inst Quim, BR-13083970 Campinas, SP - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | Talanta; v. 208, FEB 1 2020. |
| Web of Science Citations: | 0 |
| Abstract | |
Disposable electrochemical sensors using sustainable and cheap materials are an exciting alternative to produce new kinds of sensing platforms. Waterproof paper (WP) is a biodegradable and biocompatible material that allows dropped of the sample on its surface without absorption by fibers. Also, WP can be used for miniaturized sensors construction. In this work, a conductive ink was produced with nail polish and graphite powder, using the WP as the sensor substrate for paracetamol (PAR) and melatonin (MEL) voltammetric determination. PAR is a pharmaceutical commonly used in high doses for the relief of pain and fever, and MEL is a hormone related to several diseases besides a direct relation to sleep quality. Using differential pulse voltammetry for PAR determination, the WP sensor showed a linear response in the concentration ranging from 0.50 mu mol L-1 to 100 mu mol L-1 with a limit of detection (LOD) of 53.6 nmol L-1. Square wave voltammetry was applied for MEL determination, and the proposed electrode presented linear response ranging from 0.80 mu mol L-1 to 100 mu mol L-1 and LOD of 32.5 nmol L-1. The sensor showed excellent repeatability and reproducibility for consecutive measurements. Then, the disposable WP sensor was successfully applied in the determination of PAR and MEL in pharmaceutical and biological samples, with recovery values, above 91.1%. The described architecture allowed the manufacture of a disposable, simple, and low-cost electroanalytical device that can be used for electrochemical sensing. (AU) | |
| FAPESP's process: | 17/21898-6 - New conductive devices for application in electrochemical sensing and biosensing |
| Grantee: | Bruno Campos Janegitz |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 18/02162-1 - Disposable sensors using waterproof paper and graphite conductive ink for the detection of pharmaceutical interest analyses |
| Grantee: | Jéssica Rocha Camargo |
| Support Opportunities: | Scholarships in Brazil - Scientific Initiation |
| FAPESP's process: | 17/21097-3 - Bee-agriculture interactions: perspectives to sustainable use |
| Grantee: | Osmar Malaspina |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |
| FAPESP's process: | 19/00473-2 - Development of 3-dimensional (3D) printed electrochemical biosensors with PLA polymer and graphene for the determination of biomolecules and diagnosis of diseases |
| Grantee: | Cristiane Kalinke |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 13/22127-2 - Development of novel materials strategic for integrated analytical devices |
| Grantee: | Lauro Tatsuo Kubota |
| Support Opportunities: | Research Projects - Thematic Grants |