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Effect of pulp oil and tea of leaves from avocado Hass variety associated with physical activity in the treatment of obesity induced by high-fat diet

Grant number: 15/13320-9
Support Opportunities:Regular Research Grants
Start date: March 01, 2016
End date: February 28, 2018
Field of knowledge:Health Sciences - Nutrition - Nutrition Biochemistry
Principal Investigator:Mário Roberto Maróstica Junior
Grantee:Mário Roberto Maróstica Junior
Host Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

Associated with a large number of diseases, obesity is directly related to the development of metabolic and endocrine disorders that have severe consequences such as peripheral insulin resistance, type 2 diabetes and non-alcoholic fatty liver disease. Seventy-one species of medicinal plants are used in the Brazilian public health system, due to cultural and traditional use for the treatment of diseases related to obesity. The avocado is a sheet of such medicinal plants that contain bioactive compounds, such as flavonoids, which are able to decrease the inflammatory subclinical obesity in order to improve the action of insulin in type 2 diabetes. The avocado pulp oil despite now marketed in the XXI century, already has records of positive effects on human health with the potential to reduce the effects of Non-alcoholic fatty liver disease, because it contains carotenoids, phytosterols and monounsaturated fatty acid in quantity higher than that of olive oil. Not only bioactive compounds from plants and oils are important in the treatment of obesity and its comorbidities. A balanced diet associated with physical activity potentiate the beneficial effects on metabolic recovery and help promote weight reduction, improvement of the inflammatory and oxidative improves insulin action and glucose uptake, and is the initial treatment for Non-alcoholic fatty liver disease. Within this scope, this paper aims to evaluate the effect of oil pulp, leaf tea of avocado Hass variety and physical activity in obesity and subclinical inflammation of male Wistar rats fed high-fat diet from weaning to adulthood. (AU)

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Scientific publications (41)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BUSCH FURLAN, CIBELE PRISCILA; VALLE, SANDRA COSTA; OSTMAN, ELIN; MAROSTICA, JR., MARIO ROBERTO; TOVAR, JUSCELINO. Inclusion of Hass avocado-oil improves postprandial metabolic responses to a hypercaloric-hyperlipidic meal in overweight subjects. Journal of Functional Foods, v. 38, n. A, p. 349-354, . (15/13320-9)
TARONE, ADRIANA GADIOLI; SILVA, ERIC KEVEN; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, JR., MARIO ROBERTO. Inulin/fructooligosaccharides/pectin-based structured systems: Promising encapsulating matrices of polyphenols recovered from jabuticaba peel. FOOD HYDROCOLLOIDS, v. 111, . (15/50333-1, 15/13320-9)
MACHADO, ANA PAULA DA FONSECA; DO NASCIMENTO, ROBERTO DE PAULA; ALVES, MARIANA DA ROCHA; REGUENGO, LIVIA MATEUS; MAROSTICA JUNIOR, MARIO ROBERTO. razilian tucuma-do-Amazonas (Astrocaryum aculeatum) and tucuma-do-Para (Astrocaryum vulgare) fruits: bioactive composition, health benefits, and technological potentia. Food Research International, v. 151, . (18/11069-5, 19/25048-2, 19/03228-9, 17/23657-6, 15/50333-1, 15/13320-9)
DE PAULA DO NASCIMENTO, ROBERTO; DA FONSECA MACHADO, ANA PAULA; LIMA, VERENA SILVA; TOMAZINI MUNHOZ MOYA, AMANDA MARIA; REGUENGO, LIVIA MATEUS; BOGUSZ JUNIOR, STANISLAU; LEAL, RAQUEL FRANCO; CAO-NGOC, PHU; ROSSI, JEAN CHRISTOPHE; LECLERCQ, LAURENT; et al. Chemoprevention with a tea from hawthorn (Crataegus oxyacantha) leaves and flowers attenuates colitis in rats by reducing inflammation and oxidative stress. FOOD CHEMISTRY-X, v. 12, . (15/50333-1, 15/13320-9, 18/11069-5, 17/23657-6)
FUENTES, EDUARDO; TROSTCHANSKY, ANDRES; REGUENGO, LIVIA M.; JUNIOR, MARIO R. M.; PALOMO, IVAN. Antiplatelet Effects of Bioactive Compounds Present in Tomato Pomace. CURRENT DRUG TARGETS, v. 22, n. 15, p. 1716-1724, . (18/11069-5, 15/50333-1, 15/13320-9)
SANZANA, SIGRID; RODRIGUEZ, LYANNE; BARRAZA BARRIONUEVO, HAYLEEN; ALBORNOZ POBLETE, CESAR; MAROSTICA JUNIOR, MARIO ROBERTO; FUENTES, EDUARDO; PALOMO, IVAN. ntiplatelet Activity of Cucurbita maxim. JOURNAL OF MEDICINAL FOOD, . (18/11069-5, 15/50333-1, 15/13320-9)
PASCOAL, GABRIELA DE FREITAS LAIBER; GERALDI, MARINA VILAR; MAROSTICA, MARIO ROBERTO, JR.; ONG, THOMAS PRATES. Effect of Paternal Diet on Spermatogenesis and Offspring Health: Focus on Epigenetics and Interventions with Food Bioactive Compounds. NUTRIENTS, v. 14, n. 10, p. 18-pg., . (15/13320-9, 18/11069-5, 19/13465-8, 15/50333-1, 19/12244-8, 13/07914-8)
DA SILVA-MAIA, JULIANA KELLY; NAGALINGAM, ARUMUGAM; CAZARIN, CINTHIA BAIL BETIM; MAROSTICA JR, MARIO ROBERTO; SHARMA, DIPALI. Jaboticaba (Myrciaria jaboticaba) peel extracts induce reticulum stress and apoptosis in breast cancer cells. FOOD CHEMISTRY: MOLECULAR SCIENCES, v. 6, p. 8-pg., . (19/13465-8, 15/50333-1, 18/11069-5, 15/13320-9)
DO NASCIMENTO, ROBERTO DE PAULA; POLEZI, GABRIELE; RIZZATO, JULIA SOTO; BATISTA, PATRICIA BERILLI; DOS SANTOS, NATHALIA MEDINA; LOUBET FILHO, PAULO SERGIO; REGUENGO, LIVIA MATEUS; MORARI, JOSEANE; JUNIOR, STANISLAU BOGUSZ; RIBEIRO PAIOTTI, ANA PAULA; et al. Brazilian berries prevent colitis induced in obese mice by reducing the clinical signs and intestinal damage. FOOD BIOSCIENCE, v. 44, n. B, . (15/50333-1, 15/13320-9, 18/11069-5)
ALEXANDRINO, THAIS DOLFINI; TOMAZINI MUNHOZ MOYA, AMANDA MARIA; MADUREIRA DE MEDEIROS, TIAGO DANIEL; MORARI, JOSEANE; VELLOSO, LICIO AUGUSTO; LEAL, RAQUEL FRANCO; MAROSTICA, MARIO ROBERTO; PASTORE, GLAUCIA MARIA; BETIM CAZARIN, CINTHIA BAU; BICAS, JULIANO LEMOS. Anti-inflammatory effects of monoterpenoids in rats with TNBS-induced colitis. PHARMANUTRITION, v. 14, . (16/21619-7, 15/50333-1, 15/13320-9, 18/11069-5)
ARRUDA, HENRIQUE SILVANO; LOPES ARAUJO, MARIA VITORIA; MAROSTICA JUNIOR, MARIO ROBERTO. Underexploited Brazilian Cerrado fruits as sources of phenolic compounds for diseases management: A review. FOOD CHEMISTRY: MOLECULAR SCIENCES, v. 5, p. 22-pg., . (15/13320-9, 20/08761-4, 18/11069-5, 19/13465-8, 15/50333-1)
CARNEIRO, MARA JUNQUEIRA; PINHEIRO, GUILHERME PEREZ; BASEGGIO, ANDRESSA MARA; MAROSTICA JR, MARIO ROBERTO; SAWAYA, ALEXANDRA CHRISTINE HELENA FRANKLAND. Chemical Composition and Antioxidant Activity of Essential Oil from Male and Female Schinus terebinthifolius. PHARMACOGNOSY RESEARCH, v. 15, n. 3, p. 8-pg., . (15/13320-9, 16/11524-9, 22/09493-9, 15/50333-1, 19/13465-8, 18/11069-5)
ARRUDA, HENRIQUE SILVANO; BORSOI, FELIPE TECCHIO; ANDRADE, AMANDA CRISTINA; PASTORE, GLAUCIA MARIA; MAROSTICA JUNIOR, MARIO ROBERTO. Scientific Advances in the Last Decade on the Recovery, Characterization, and Functionality of Bioactive Compounds from the Araticum Fruit (Annona crassiflora Mart.). PLANTS-BASEL, v. 12, n. 7, p. 39-pg., . (15/13320-9, 15/50333-1, 19/13465-8, 20/08761-4, 18/11069-5)
BUSCH FURLAN, CIBELE PRISCILA; VALLE, SANDRA COSTA; OSTMAN, ELIN; MAROSTICA, MARIO ROBERTO, JR.; TOVAR, JUSCELINO. Inclusion of Hass avocado-oil improves postprandial metabolic responses to a hypercaloric-hyperlipidic meal in overweight subjects. Journal of Functional Foods, v. 38, p. 6-pg., . (15/13320-9)
BASEGGIO, ANDRESSA MARA; KIDO, LARISSA AKEMI; VIGANO, JULIANE; CARNEIRO, MARA JUNQUEIRA; LAMAS, CELINA DE ALMEIDA; MARTINEZ, JULIAN; SAWAYA, ALEXANDRA CHRISTINE HELENA FRANKLAND; CAGNON, VALERIA HELENA ALVES; MAROSTICA JUNIOR, MARIO ROBERTO. Systemic antioxidant and anti-inflammatory effects of yellow passion fruit bagasse extract during prostate cancer progression. JOURNAL OF FOOD BIOCHEMISTRY, . (17/01573-5, 18/11069-5, 15/13320-9, 15/50333-1, 19/13465-8)
REGUENGO, LIVIA MATEUS; SALGACO, MATEUS KAWATA; SIVIERI, KATIA; MAROSTICA JUNIOR, MARIO ROBERTO. gro-industrial by-products: Valuable sources of bioactive compound. Food Research International, v. 152, . (15/50333-1, 19/25048-2, 18/11069-5, 15/13320-9)
DO NASCIMENTO, ROBERTO DE PAULA; REGUENGO, LIVIA MATEUS; DA FONSECA MACHADO, ANA PAULA; MAROSTICA JUNIOR, MARIO ROBERTO. he preventive and therapeutic potential of native Brazilian fruits on colorectal cance. FOOD BIOSCIENCE, v. 46, . (18/11069-5, 19/03228-9, 17/23657-6, 15/50333-1, 19/25048-2, 15/13320-9)
ARRUDA, HENRIQUE SILVANO; NERI-NUMA, IRAMAIA ANGELICA; KIDO, LARISSA AKEMI; MAROSTICA JUNIOR, MARIO ROBERTO; PASTORE, GLAUCIA MARIA. Recent advances and possibilities for the use of plant phenolic compounds to manage ageing-related diseases. Journal of Functional Foods, v. 75, . (18/11069-5, 15/13320-9, 17/01573-5, 15/50333-1)
PECANHA, JULIANA DE SOUZA; DOS SANTOS, NATHALIA MEDINA; MAROSTICA JUNIOR, MARIO ROBERTO; MICHELETTI, ANA CAMILA; LIAO, LUCIANO MORAIS; ALCANTARA, GLAUCIA BRAZ. NMR-based metabolomics of dried berries in comparison with dietary supplements. Journal of Pharmaceutical and Biomedical Analysis, v. 209, . (15/13320-9, 18/11069-5, 19/13465-8, 15/50333-1)
KIDO, LARISSA AKEMI; HAHM, EUN-RYEONG; KIM, SU-HYEONG; BASEGGIO, ANDRESSA MARA; CAGNON, VALERIA HELENA ALVES; SINGH, SHIVENDRA V.; MAROSTICA, JR., MARIO ROBERTO. Prevention of Prostate Cancer in Transgenic Adenocarcinoma of the Mouse Prostate Mice by Yellow Passion Fruit Extract and Antiproliferative Effects of Its Bioactive Compound Piceatannol. JOURNAL OF CANCER PREVENTION, v. 25, n. 2, p. 87-99, . (18/11069-5, 15/13320-9, 15/50333-1, 18/09793-7)
ARRUDA, HENRIQUE SILVANO; SILVA, ERIC KEVEN; PEIXOTO ARAUJO, NAYARA MACEDO; PEREIRA, GUSTAVO ARAUJO; PASTORE, GLAUCIA MARIA; MAROSTICA JUNIOR, MARIO ROBERTO. Anthocyanins Recovered from Agri-Food By-Products Using Innovative Processes: Trends, Challenges, and Perspectives for Their Application in Food Systems. Molecules, v. 26, n. 9, . (19/27103-0, 19/13465-8, 18/11069-5, 18/10608-0, 15/13320-9, 15/50333-1)
LAIBER PASCOAL, GABRIELA DE FREITAS; DE ALMEIDA SOUSA CRUZ, MARTA ANGELA; DE ABREU, JOEL PIMENTEL; BARROS SANTOS, MILLENA CRISTINA; FANARO, GUSTAVO BERNARDES; MAROSTICA JUNIOR, MARIO ROBERTO; SILVA, OTNIEL FREITAS; ALVES MOREIRA, RICARDO FELIPE; CAMERON, LUIZ CLAUDIO; LARRAZ FERREIRA, MARIANA SIMOES; et al. Evaluation of the antioxidant capacity, volatile composition and phenolic content of hybrid Vitis vinifera L. varieties sweet sapphire and sweet surprise. Food Chemistry, v. 366, . (19/13465-8, 18/11069-5, 15/50333-1, 15/13320-9)
BARROS MARIUTTI, LILIAN REGINA; REBELO, KEMILLA SARMENTO; BISCONSIN-JUNIOR, ANTONIO; DE MORAIS, JANNE SANTOS; MAGNANI, MARCIANE; MALDONADE, IRIANI RODRIGUES; MADEIRA, NUNO RODRIGO; TIENGO, ANDREA; MAROSTICA, JR., MARIO ROBERTO; BETIM CAZARIN, CINTHIA BAU. The use of alternative food sources to improve health and guarantee access and food intake. Food Research International, v. 149, . (19/13465-8, 18/11069-5, 15/50333-1, 15/13320-9)
GERALDI, MARINA VILAR; BETIM CAZARIN, CINTHIA BAU; DIAS-AUDIBERT, FLAVIA LUISA; PEREIRA, GUSTAVO ARAUJO; CARVALHO, GABRIELA GUIMARAES; KABUKI, DIRCE YORIKA; CATHARINO, RODRIGO RAMOS; PASTORE, GLAUCIA MARIA; BEHRENS, JORGE HERMAN; CRISTIANINI, MARCELO; et al. Influence of high isostatic pressure and thermal pasteurization on chemical composition, color, antioxidant properties and sensory evaluation of jabuticaba juice. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 139, . (15/50333-1, 18/11069-5, 19/12244-8, 15/13320-9)
AGUIAR, LAIS MARINHO; BICAS, JULIANO LEMOS; FUENTES, EDUARDO; ALARCON, MARCELO; GONZALEZ, IVAN PALOMO; PASTORE, GLAUCIA MARIA; MAROSTICA JUNIOR, MARIO ROBERTO; CAZARIN, CINTHIA BAU BETIM. Non-nutrients and nutrients from Latin American fruits for the prevention of cardiovascular diseases. Food Research International, v. 139, . (18/11069-5, 15/50333-1, 15/13320-9)
TARONE, ADRIANA GADIOLI; SILVA, ERIC KEVEN; BARROS, HELENA DIAS DE FREITAS QUEIROZ; CAZARIN, CINTHIA BAU BETIM; JUNIOR, MARIO ROBERTO MAROSTICA. High-intensity ultrasound-assisted recovery of anthocyanins from jabuticaba by-products using green solvents: Effects of ultrasound intensity and solvent composition on the extraction of phenolic compounds. Food Research International, v. 140, . (15/50333-1, 15/13320-9)
MACHADO, ANA PAULA DA FONSECA; ALVES, MARIANA DA ROCHA; NASCIMENTO, ROBERTO DE PAULA DO; REGUENGO, LIVIA MATEUS; MAROSTICA JR, MARIO ROBERTO. Antiproliferative effects and main molecular mechanisms of Brazilian native fruits and their by-products on lung cancer. Food Research International, v. 162, p. 9-pg., . (17/23657-6, 19/03228-9, 15/50333-1, 19/12244-8, 15/13320-9, 18/11069-5)
KIDO, LARISSA AKEMI; ROSSETTO, ISABELA MARIA URRA; BASEGGIO, ANDRESSA MARA; CHIAROTTO, GABRIELA BORTOLANZA; ALVES, LETICIA FERREIRA; SANTOS, FELIPE RABELO; LAMAS, CELINA DE ALMEIDA; MAROSTICA, MARIO ROBERTO; CAGNON, VALERIA HELENA ALVES. Brazilian Berry Extract Differentially Induces Inflammatory and Immune Responses in Androgen Dependent and Independent Prostate Cancer Cells. JOURNAL OF CANCER PREVENTION, v. 27, n. 3, p. 10-pg., . (18/04579-7, 15/50333-1, 19/13465-8, 15/13320-9, 18/11069-5)
REBELO, KEMILLA SARMENTO; COIMBRA NUNEZ, CARLA EVELYN; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, MARIO ROBERTO; KRISTIANSEN, KARSTEN; DANNESKIOLD-SAMSOE, NIELS BANHOS. Pot-pollen supplementation reduces fasting glucose and modulates the gut microbiota in high-fat/high-sucrose fed C57BL/6 mice. FOOD & FUNCTION, v. 13, n. 7, p. 11-pg., . (15/13320-9, 15/50333-1, 19/13465-8, 18/11069-5)
LONGO, MARJORIE BARCHA; LAMAS, CELINA DE ALMEIDA; ROSSETTO, ISABELA URRA; NOGUEIRA-LIMA, ELLEN; COLLARES-BUSATTO, CARLA BEATRIZ; MAROSTICA JUNIOR, MARIO ROBERTO; ALVES CAGNON QUITETE, VALERIA HELENA. Brazilian Berry Extract Chemopreventive Action: Hormone Receptors as a Target to Mitigate Aging Prostatic Disorders.. Brazilian Archives of Biology and Technology, v. 66, p. 12-pg., . (15/25714-1, 15/13320-9, 18/11069-5, 15/24793-5, 18/04579-7, 15/50333-1)
CAETANO, PATRICIA A.; DO NASCIMENTO, TATIELE C.; FERNANDES, ANDRESSA S.; NASS, PRICILA P.; VIEIRA, KAREM R.; MAROSTICA JUNIOR, MARIO R.; JACOB-LOPES, EDUARDO; ZEPKA, LEILA Q.. Microalgae-based polysaccharides: Insights on production, applications, analysis, and future challenges. BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY, v. 45, p. 18-pg., . (19/13465-8, 15/50333-1, 18/11069-5, 15/13320-9)
SOUZA, ALANN THAFFARELL PORTILHO; FREITAS, GILEADE PEREIRA; LOPES, HELENA BACHA; TOTOLI, GABRIELA GUARALDO CAMPOS; TARONE, ADRIANA GADIOLI; MAROSTICA-JUNIOR, MARIO ROBERTO; ROSA, ADALBERTO LUIZ; BELOTI, MARCIO MATEUS. Jabuticaba peel extract modulates adipocyte and osteoblast differentiation of MSCs from healthy and osteoporotic rats. JOURNAL OF BONE AND MINERAL METABOLISM, v. 39, n. 2, . (15/13320-9, 17/20349-9, 18/11069-5, 15/50333-1, 17/12622-7)
VALLE, MARIA C. P. R.; VIEIRA, ISABEL A.; FINO, LUCIANA C.; GALLINA, DARLILA A.; ESTEVES, ANDREA M.; DA CUNHA, DIOGO T.; CABRAL, LUCELIA; BENATTI, FABIANA B.; MAROSTICA JUNIOR, MARIO R.; BATISTA, ANGELA G.; et al. Immune status, well-being and gut microbiota in military supplemented with synbiotic ice cream and submitted to field training: a randomised clinical trial. BRITISH JOURNAL OF NUTRITION, v. 126, n. 12, p. 1794-1808, . (18/18366-5, 15/50333-1, 17/25007-9, 18/11069-5, 15/13320-9)
MARCELINO, GABRIELA; HIANE, PRISCILA AIKO; POTT, ARNILDO; DE OLIVEIRA FILIU, WANDER FERNANDO; CAIRES, ANDERSON R. L.; MICHELS, FLAVIO S.; JUNIOR, MARIO R. MAROSTICA; SANTOS, NATHALIA M. S.; NUNES, ANGELA A.; OLIVEIRA, LINCOLN C. S.; et al. Characterization of Buriti (Mauritia flexuosa) Pulp Oil and the Effect of Its Supplementation in an In Vivo Experimental Model. NUTRIENTS, v. 14, n. 12, p. 22-pg., . (15/50333-1, 15/13320-9, 18/11069-5, 19/13465-8)
MOREIRA, RAFAEL CHELALA; DE MELO, RAYANNE PRISCILLA FRANCA; MARTINEZ, JULIAN; MAROSTICA JUNIOR, MARIO ROBERTO; PASTORE, GLAUCIA MARIA; ZORN, HOLGER; BICAS, JULIANO LEMOS. Supercritical CO2 as a Valuable Tool for Aroma Technology. Journal of Agricultural and Food Chemistry, v. 71, n. 24, p. 12-pg., . (21/01008-1, 15/13320-9, 20/06814-3, 17/11245-5, 15/50333-1, 19/13465-8, 18/11069-5)
DO NASCIMENTO, ROBERTO DE PAULA; RIZZATO, JULIA SOTO; POLEZI, GABRIELE; MOYA, AMANDA MARIA TOMAZINI MUNHOZ; SILVA, MILENA FERREIRA; MACHADO, ANA PAULA DA FONSECA; FRANCHI JUNIOR, GILBERTO CARLOS; BORGUINI, RENATA GALHARDO; SANTIAGO, MANUELA CRISTINA PESSANHA DE ARAUJO; PAIOTTI, ANA PAULA RIBEIRO; et al. Freeze-dried jaboticaba (Myrciaria jaboticaba) peel powder, a rich source of anthocyanins and phenolic acids, mitigates inflammation-driven colorectal cancer in mice. FOOD BIOSCIENCE, v. 53, p. 10-pg., . (15/13320-9, 20/00414-3, 19/03228-9, 15/50333-1, 17/23657-6, 18/11069-5)
REGUENGO, LIVIA MATEUS; DO NASCIMENTO, ROBERTO DE PAULA; MACHADO, ANA PAULA DA FONSECA; MAROSTICA JUNIOR, MARIO ROBERTO. Signaling pathways and the potential anticarcinogenic effect of native Brazilian fruits on breast cancer. Food Research International, v. 155, p. 13-pg., . (15/13320-9, 18/11069-5, 19/03228-9, 17/23657-6, 15/50333-1, 19/25048-2, 19/12244-8)
DO NASCIMENTO, ROBERTO DE PAULA; MOYA, AMANDA MARIA TOMAZINI MUNHOZ; MACHADO, ANA PAULA DA FONSECA; GERALDI, MARINA VILAR; DIEZ-ECHAVE, PATRICIA; VEZZA, TERESA; GALVEZ, JULIO; CAZARIN, CINTHIA BAIL BETIM; MAROSTICA, JR., MARIO ROBERTO. Review on the potential application of non-phenolic compounds from native Latin American food byproducts in inflammatory bowel diseases. Food Research International, v. 139, . (15/50333-1, 15/13320-9, 19/12244-8, 17/23657-6, 18/11069-5)
DE OLIVEIRA, ELLEN CRISTINA SOUZA; DALMAU, LESVI MOYA; DE ALMEIDA COSTA, CELSO ACACIO RODRIGUES; DE ALMEIDA JUNIOR, LUIZ DOMINGUES; BALLARD, CINTIA REIS; MAROSTICA JUNIOR, MARIO ROBERTO; STAHL, MARCELLA APARECIDA; GRIMALDI, RENATO; WITAICENIS, ALINE; DI STASI, LUIZ CLAUDIO. Dietary intervention with avocado (Persea americana Mill.) ameliorates intestinal inflammation induced by TNBS in rats. INFLAMMOPHARMACOLOGY, v. N/A, p. 14-pg., . (19/13465-8, 15/50333-1, 18/11069-5, 15/13320-9)
DE PAULA DO NASCIMENTO, ROBERTO; DA FONSECA MACHADO, ANA PAULA; GALVEZ, JULIO; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, MARIO ROBERTO. Ulcerative colitis: Gut microbiota, immunopathogenesis and application of natural products in animal models. Life Sciences, v. 258, p. 22-pg., . (17/23657-6, 15/13320-9, 18/11069-5, 15/50333-1)