Application of high pressure technology to obtain bioproducts: assembly of a multi-purpose equipment and development of processes for barbatimão

• Grant number: 20/07575-2
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2021
• End date: July 31, 2023
• Field of knowledge: Engineering - Chemical Engineering
• Principal Investigator: Priscilla Carvalho Veggi
• Grantee: Priscilla Carvalho Veggi
• Host Institution: Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF). Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Diadema , SP, Brazil
• Associated researchers: Juliane Viganó ; Mara Elga Medeiros Braga ; Maria Angela de Almeida Meireles Petenate ; Mariana Agostini de Moraes
• Associated research grant(s): 25/02231-7 - 14 th International Symposium on Supercritical Fluids, AR.EXT; 24/16645-5 - XVIII Latin American Polymer Symposium, XV Ibero-American Polymer Congress and XI Colloquium on Macromolecules, AR.EXT; 23/07906-7 - VI Iberoamerican Conference on Supercritical Fluids (PROSCIBA 2023), AR.EXT

Abstract

This project aims to develop a multi-purpose equipment to operate at high pressure in order to obtain products applicable to the pharmaceutical, cosmetic, and food industries. High pressure technology is emerging and widely used to obtain high-value products from natural sources. During the last decades, numerous researches have been carried out worldwide applying high-pressure technologies; and new applications are often proposed in the literature. The results have shown the viability of these technologies in the recovery and processing of active compounds through clean and environment-friendly methods. In this context, this project suggests the assembly of a multipurpose equipment for high-pressure processes, including the operations of extraction (supercritical fluids and pressurized liquids), separation (supercritical adsorption), impregnation and supercritical drying. In this way, a single unit will allow the study of different processes under high pressure, providing a better cost-benefit ratio associated with this technology. Precisely for this project, in addition to the assembly of the equipment, it is intended to apply high-pressure extraction techniques to obtain an extract rich in bioactive compounds from the bark of the barbatimão tree (Stryphnodendron adstringens (Mart.) Coville) and study the extract impregnation in solid materials. The processes will be evaluated in terms of extraction and impregnation yield, total phenolic and tannins content, and identification and quantification of target compounds by chromatography. Solid materials will be evaluated before and after the processing by X-ray diffraction, Fourier-transform infrared spectroscopy, and scanning electron microscopy. It is expected with the results of this project to obtain biologically safe products applicable in several formulations. (AU)

Scientific publications

(12)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE BRITO, VIVIAN P.; DE SOUZA RIBEIRO, MAURICIO M.; VIGANO, JULIANE; DE MORAES, MARIANA A.; VEGGI, PRISCILLA C.. Silk Fibroin Hydrogels Incorporated with the Antioxidant Extract of Stryphnodendron adstringens Bark. POLYMERS, v. 14, n. 22, p. 15-pg., 2022-11-01. (20/15774-5, 20/08212-0, 20/07575-2)

VIGANO, JULIANE; DE AGUIAR, ANA CAROLINA; VEGGI, PRISCILLA CARVALHO; SANCHES, VITOR L.; ROSTAGNO, MAURICIO ARIEL; MARTINEZ, JULIAN. Techno-economic evaluation for recovering phenolic compounds from acai (Euterpe oleracea) by-product by pressurized liquid extraction. JOURNAL OF SUPERCRITICAL FLUIDS, v. 179, JAN 2022. (20/07575-2, 17/23670-2, 16/18910-1, 19/13496-0, 20/15774-5)

RODRIGUES, CAMILA LOPES; TOMODA, BRUNO THORIHARA; VIGANO, JULIANE; BRAGA, ANNA RAFAELA CAVALCANTE; DE MORAES, MARIANA AGOSTINI; VEGGI, PRISCILLA CARVALHO. Production and Characterization of Silk Fibroin-Aloe vera Hydrogel: A Study on Extraction, Hydrogel Properties, and Release Mechanism. ACS OMEGA, v. 9, n. 51, p. 11-pg., 2024-12-13. (16/17555-3, 20/08212-0, 20/07575-2)

DE NOVAIS, NATHALIA S.; RIBEIRO, MAURICIO M. DE SOUZA; VIGANO, JULIANE; COELHO, DEBORAH B.; FALCAO, LUCAS DE S.; DE MORAES, MARIANA A.; VEGGI, PRISCILA C.. High- and low-pressure fixed bed extraction behaviors to obtain phenolic compounds from barbatimão (Stryphnodendron adstringens) bark. SUSTAINABLE CHEMISTRY AND PHARMACY, v. 36, p. 13-pg., 2023-10-18. (20/15774-5, 20/07575-2, 20/00813-5)

VARDANEGA, RENATA; FERREIRA, WILSON S.; VIGANO, JULIANE; PRADO, JULIANA M.; MORANO, ROGERIO S.; VEGGI, PRISCILLA C.. Exploring the economic viability of Jatoba (Hymenaea courbaril L.) bark extraction: A comparative study. Separation and Purification Technology, v. 350, p. 12-pg., 2024-05-16. (20/15774-5, 08/10986-2, 20/07575-2)

VEGGI, PRISCILLA C.; HATAMI, TAHMASB; CAMPOS, LEONARDO F.; MAZUR, LUCIANA P.; DO CARMO, LUANA E.; MEI, LUCIA H. I.; VIGANO, JULIANE. High-pressure liquid impregnation of barbatimao bark extract into biopolymeric membrane composed of PBS/PLA and Cloisite 20 A blend. JOURNAL OF SUPERCRITICAL FLUIDS, v. 216, p. 9-pg., 2025-02-01. (20/07575-2)

FERREIRA, WILSON S.; VIGANO, JULIANE; VEGGI, PRISCILLA C.. Economic assessment of emerging extraction techniques: hybridization of high-pressure extraction and low-frequency ultrasound to produce piceatannol-rich extract from passion fruit bagasse. CHEMICAL ENGINEERING AND PROCESSING, v. 174, p. 10-pg., 2022-03-11. (20/15774-5, 20/07575-2)

VARDANEGA, RENATA; CEREZAL-MEZQUITA, PEDRO; VEGGI, PRISCILLA CARVALHO. Supercritical fluid extraction of astaxanthin-rich extracts from Haematococcus pluvialis: Economic assessment. Bioresource Technology, v. 361, p. 8-pg., 2022-07-29. (20/07575-2)

RIBEIRO, MAURICIO M. DE SOUZA; VIGANO, JULIANE; DE NOVAIS, NATHALIA STAHL; MESQUITA, LEONARDO M. DE SOUZA; KAMIKAWACHI, RENAN CANUTE; VILEGAS, WAGNER; LOPES, PATRICIA SANTOS; DA SILVA, CAMILA SOARES; ROSTAGNO, MAURICIO ARIEL; VEGGI, PRISCILA CARVALHO. The effect of ultrasound on improving the extraction of tannins from the Stryphnodendron adstringens bark. SUSTAINABLE CHEMISTRY AND PHARMACY, v. 33, p. 14-pg., 2023-03-10. (20/15774-5, 18/14582-5, 19/13496-0, 20/07575-2)

SILVA, ISABELA A.; CARMO, LUANA E.; SINNECKER, PATRICIA; CAVALARI, ALINE A.; VEGGI, PRISCILLA C.; PERRECHIL, FABIANA. Physicochemical characterization of Dillenia indica fruits and exploration of extraction methods to obtain reducing compounds and pectin. APPLIED FOOD RESEARCH, v. 4, n. 2, p. 10-pg., 2024-09-27. (18/15539-6, 20/07575-2, 19/08975-7)

FALCAO, LUCAS DE SOUZA; COELHO, DEBORAH BENTO; VEGGI, PRISCILLA CARVALHO; CAMPELO, PEDRO HENRIQUE; ALBUQUERQUE, PATRICIA MELCHIONNA; DE MORAES, MARIANA AGOSTINI. Starch as a Matrix for Incorporation and Release of Bioactive Compounds: Fundamentals and Applications. POLYMERS, v. 14, n. 12, p. 16-pg., 2022-06-01. (20/08212-0, 20/07575-2)

DE SOUZA RIBEIRO, MAURICIO M.; DOS SANTOS, LUANA C.; DE NOVAIS, NATHALIA S.; VIGANO, JULIANE; VEGGI, PRISCILA C.. An evaluative review on Stryphnodendron adstringens extract composition: Current and future perspectives on extraction and application. INDUSTRIAL CROPS AND PRODUCTS, v. 187, p. 21-pg., 2022-07-18. (20/15774-5, 20/07575-2, 20/00813-5)