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Grant number: 15/11984-7
Support type:Regular Research Grants
Duration: November 01, 2015 - April 30, 2018
Field of knowledge:Agronomical Sciences - Food Science and Technology - Food Engineering
Principal researcher:Miriam Dupas Hubinger
Grantee:Miriam Dupas Hubinger
Home Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Assoc. researchers:Ana Silvia Prata


Increased incidence of diabetes, hypertension and cancer has caused changes in dietary habits of population, which impacts on a rise of the demand for functional foods, that is, foods that present functions besides nutrition. Beneficial effects for health are reached because of the presence of bioactive compounds (like polyunsaturated fatty acids, carotenoids, polyphenolics, probiotics and prebiotics) in such food. Resveratrol is a phenolic compound which is found in plant sources. Its antioxidant, antimicrobial, anti diabetes and antiobesity effects have been well reported in literature. Chia seed oil presents a high concentration of polyunsaturated fatty acids omega-3 and omega-6. These compounds are important on the prevention of inflammatory diseases, hypertension, diabetes and coronary disease. The use of oil-in-water (O/W) emulsions as encapsulants for lipophilic compounds can bring great results for promoting protection against external factors like oxygen and light; taste masking; and as delivery systems. Drying such products by spray drying technique is advantageous considering storage stability and transportation. The present project has as main goal the production of spray dried microparticles loaded with lipophilic cores (resveratrol or chia seed oil), by the atomization of simple and multilayer O/W emulsions, which will be obtained through the use of different mechanical devices (rotor-stator, high pressure homogenizer and sonication). Emulsions and microparticles will be characterized in order to compare the effects of emulsification methods on microparticles properties. (AU)

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Scientific publications (17)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DA SILVA ANTHERO, ANA GABRIELA; COMUNIAN, TALITA ALINE; BEZERRA, EVELING OLIVEIRA; HUBINGER, MIRIAM DUPAS. Barley Malt Esterification after Ultrasound and Stearic Acid Treatment: Characterization and Use as Stabilizing Agent in Oil-in-Water Emulsions. Food and Bioprocess Technology, v. 14, n. 2 JAN 2021. Web of Science Citations: 0.
CONSOLI, LARISSA; HUBINGER, MIRIAM DUPAS; DRAGOSAVAC, MARIJANA M. Encapsulation of resveratrol using Maillard conjugates and membrane emulsification. Food Research International, v. 137, NOV 2020. Web of Science Citations: 0.
DA SILVA ANTHERO, ANA GABRIELA; BEZERRA, EVELING OLIVEIRA; COMUNIAN, TALITA ALINE; PROCOPIO, FERNANDA RAMALHO; HUBINGER, MIRIAM DUPAS. Effect of modified starches and gum arabic on the stability of carotenoids in paprika oleoresin microparticles. Drying Technology, NOV 2020. Web of Science Citations: 0.
MARSON, GABRIELA VOLLET; SATURNO, RAFAELA POLESSI; COMUNIAN, TALITA ALINE; CONSOLI, LARISSA; DA COSTA MACHADO, MARIANA TEIXEIRA; HUBINGER, MIRIAM DUPAS. Maillard conjugates from spent brewer's yeast by-product as an innovative encapsulating material. Food Research International, v. 136, OCT 2020. Web of Science Citations: 0.
VELEZ-ERAZO, ELIANA MARCELA; RABELO, RENATA S. High internal phase emulsions (HIPE) using pea protein and different polysaccharides as stabilizers. FOOD HYDROCOLLOIDS, v. 105, AUG 2020. Web of Science Citations: 0.
FELTRE, GABRIELA; ALMEIDA, FLAVIA SOUZA; KAWAZOE SATO, ANA CARLA; DACANAL, GUSTAVO CESAR; HUBINGER, MIRIAM DUPAS. Alginate and corn starch mixed gels: Effect of gelatinization and amylose content on the properties and in vitro digestibility. Food Research International, v. 132, JUN 2020. Web of Science Citations: 0.
FELTRE, GABRIELA; SARTORI, TANARA; SILVA, KLYCIA F. C.; DACANAL, GUSTAVO C.; MENEGALLI, FLORENCIA C.; HUBINGER, MIRIAM D. Encapsulation of wheat germ oil in alginate-gelatinized corn starch beads: Physicochemical properties and tocopherols' stability. Journal of Food Science, v. 85, n. 7 JUN 2020. Web of Science Citations: 0.
VELEZ-ERAZO, ELIANA MARCELA; CONSOLI, LARISSA; HUBINGER, MIRIAM DUPAS. Spray drying of mono- and double-layer emulsions of PUFA-rich vegetable oil homogenized by ultrasound. Drying Technology, FEB 2020. Web of Science Citations: 0.
RABELO, RENATA S.; TAVARES, GUILHERME M.; PRATA, ANA S.; HUBINGER, MIRIAM D. Complexation of chitosan with gum Arabic, sodium alginate and kappa-carrageenan: Effects of pH, polymer ratio and salt concentration. Carbohydrate Polymers, v. 223, NOV 1 2019. Web of Science Citations: 0.
CONSOLI, LARISSA; OLIVEIRA DIAS, RAMONITA APARECIDA; DA SILVA CARVALHO, ANA GABRIELA; DA SILVA, VANESSA MARTINS; HUBINGER, MIRIAM DUPAS. Resveratrol-loaded microparticles: Assessing Maillard conjugates as encapsulating matrices. Powder Technology, v. 353, p. 247-256, JUL 15 2019. Web of Science Citations: 0.
CERQUEIRA E SILVA, KLYCIA FIDELIS; DA SILVA CARVALHO, ANA GABRIELA; RABELO, RENATA SANTOS; HUBINGER, MIRIAM DUPAS. Sacha inchi oil encapsulation: Emulsion and alginate beads characterization. FOOD AND BIOPRODUCTS PROCESSING, v. 116, p. 118-129, JUL 2019. Web of Science Citations: 0.
GUEDES SILVA, KAREN CRISTINA; KAWAZOE SATO, ANA CARLA. Sonication technique to produce emulsions: The impact of ultrasonic power and gelatin concentration. ULTRASONICS SONOCHEMISTRY, v. 52, p. 286-293, APR 2019. Web of Science Citations: 0.
CONSOLI, LARISSA; DIAS, RAMONITA A. O.; RABELO, RENATA S.; FURTADO, GUILHERME F.; SUSSULINI, ALESSANDRA; CUNHA, ROSIANE L.; HUBINGER, MIRIAM DUPAS. Sodium caseinate-corn starch hydrolysates conjugates obtained through the Maillard reaction as stabilizing agents in resveratrol-loaded emulsions. FOOD HYDROCOLLOIDS, v. 84, p. 458-472, NOV 2018. Web of Science Citations: 9.
RABELO, RENATA S.; OLIVEIRA, ISABELA F.; DA SILVA, VANESSA M.; PRATA, ANA SILVIA; HUBINGER, MIRIAM D. Chitosan coated nanostructured lipid carriers (NLCs) for loading Vitamin D: A physical stability study. International Journal of Biological Macromolecules, v. 119, p. 902-912, NOV 2018. Web of Science Citations: 3.
VELEZ-ERAZO, ELIANA MARCELA; CONSOLI, LARISSA; HUBINGER, MIRIAM DUPAS. Mono and double-layer emulsions of chia oil produced with ultrasound mediation. FOOD AND BIOPRODUCTS PROCESSING, v. 112, p. 108-118, NOV 2018. Web of Science Citations: 1.
CONSOLI, LARISSA; FURTADO, GUILHERME DE FIGUEIREDO; DA CUNHA, ROSIANE LOPES; HUBINGER, MIRIAM DUPAS. High solids emulsions produced by ultrasound as a function of energy density. ULTRASONICS SONOCHEMISTRY, v. 38, p. 772-782, SEP 2017. Web of Science Citations: 10.
NOELLO, C.; CARVALHO, A. G. S.; SILVA, V. M.; HUBINGER, M. D. Spray dried microparticles of chia oil using emulsion stabilized by whey protein concentrate and pectin by electrostatic deposition. Food Research International, v. 89, n. 1, p. 549-557, NOV 2016. Web of Science Citations: 16.
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)

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