Cromatografia líquida em uma gota e seu acoplamento com espectrometria de massas: estratégias instrumentais, desenvolvimento de materiais, automatização e aplicações analíticas

• Processo: 17/02147-0
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Data de Início da vigência: 01 de julho de 2017
• Data de Término da vigência: 30 de junho de 2023
• Área do conhecimento: Ciências Exatas e da Terra - Química - Química Analítica
• Pesquisador responsável: Fernando Mauro Lanças
• Beneficiário: Fernando Mauro Lanças
• Instituição Sede: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brasil
• Pesquisadores principais: Alvaro José dos Santos Neto ; Maria Eugênia Queiroz Nassur
• Pesquisadores associados: Gisela de Aragão Umbuzeiro ; Henrique César Santejo Silveira ; José Alexandre de Souza Crippa ; José Luiz da Costa ; Marcelo Zaiat ; Paulo Clairmont Feitosa de Lima Gomes ; Vitor Tumas
• Auxílio(s) vinculado(s): 17/21985-6 - EMU concedido no processo 17/02147-0: sistema de nano/micro-cromatografia líquida de alta eficiência hifenada a espectrometria de massas com ionização por electrospray e analisador sequencial quadrupolar (ESI-QqQ (MS/MS)) - nano/µ-LC-ESI-MS/MS, AP.EMU; 17/21984-0 - EMU concedido no processo 17/02147-0: sistema de nano-cromatografia líquida de alta eficiência hifenada a espectrometria de massas com ionização por elétrons e analisador quadrupolar (EI-Q (MS)) - nano-LC-EI-MS, AP.EMU
• Bolsa(s) vinculada(s): 22/01612-9 - Desenvolvimento de sistemas/software de planejamento de operações para equipamento automatizado de microextrações, BP.IC; 20/06526-8 - Desenvolvimento de fase monolítica orgânica com grupos trocadores de ânions e revestimento hidrofílico para determinação de homocisteína e ácido homocisteico em amostras biológicas de pacientes com a Doença de Alzheimer por in-tube SPME-UHPLC-MS/MS, BP.DR; 20/11848-4 - Uso de microextração em fase sólida em ponteiras (SPME-Tips) para análise de cocaína e produtos de biotransformação em fluido oral por cromatografia líquida acoplada à espectrometria de massas (LC-MS/MS), BP.IC; + mais bolsas vinculadas 20/07470-6 - Desenvolvimento de método miniaturizado de extração para determinação de cetamina e seus metabólitos em amostras de fluido oral usando microextração líquido-líquido dispersiva (DLLME), BP.IC; 20/07864-4 - Microtécnicas analíticas de separação para metabolômica e determinação de resíduos de agrotóxicos em tecidos e mel de abelhas nativas sem ferrão (Tetragonisca angustula), BP.DD; 19/02866-1 - Desenvolvimento de método analítico para determinação de metilfenidato, etilfenidato e ácido ritalínico em amostras de fluido oral empregando cromatografia líquida acoplada à espectrometria de massas, BP.IC; 19/22724-7 - Novas estratégias instrumentais no desenvolvimento de métodos analíticos automatizados e miniaturizados para a determinação de compostos orgânicos mediante cromatografia líquida acoplada a espectrometria de massas, BP.PD; 19/26263-4 - Desenvolvimento de colunas capilares tubulares abertas para micro e nano cromatografia líquida acopladas a espectroscopia de massas sequencial, BP.DD; 19/19485-0 - Desenvolvimento de fibras de nitinol revestidas com líquidos iônicos poliméricos zwiteriônicos para a determinação de beta-amilóides em amostras de plasma de pacientes com doença de Alzheimer através do acoplamento direto fiber-in-tube SPME e MS/MS, BP.PD; 19/04386-7 - Desenvolvimento de fase monolítica orgânica para determinação de peptídeos b-amilóide AB40 e AB42 em amostras de plasma de pacientes com a Doença de Alzheimer por UHPLC-MS/MS no modo column switching, BP.DR; 19/04057-3 - Determinação de canabinóides em amostras de óleo vegetal por extração líquido-líquido (LLE) e cromatografia líquida de ultraeficiência acoplada à espectrometria de massas em tandem (UHPLC-MS/MS), BP.IC; 19/02845-4 - Desenvolvimento de método miniaturizado de extração (microextração líquido-líquido dispersiva - DLLME) para análise de ácido 11-nor-delta-9-tetraidrocanabinol-carboxílico em amostras de urina, BP.IC; 19/08168-4 - Síntese, caracterização e avaliação de novos materiais para micro colunas de extração e seu acoplamento online com micro e nano cromatografia líquida, BP.IC; 18/11700-7 - Determinação de fármacos em águas residuárias, BP.MS; 18/11849-0 - A toxicologia das Novas Substâncias Psicoativas (NSP): epidemiologia do consumo através da análise de amostras de fluido oral e caracterização de seu metabolismo in vitro, BP.DR; 18/01448-9 - Preparo de amostras e LC-MS para análises metabolômica e expossômica: estudos e aplicação para matrizes biológicas diversas, BE.PQ; 18/06068-0 - Desenvolvimento do método SALLE-UHPLC-MS/MS no modo column switching para determinação de anandamida e 2-araquidonoilglicerol em amostras de encéfalos de ratos submetidos a modelo animal da Doença de Parkinson, BP.MS; 17/26697-9 - Padronização e validação do método SALLE/HILIC-MS/MS para a determinação de carbidopa, 3-O-metildopa, levodopa, benserazida, dopamina em amostras de plasma de pacientes Parkinsonianos, BP.IC; 17/24515-0 - Desenvolvimento de método de microextração com sorbente empacotado (MEPS) para análise de opióides sintéticos em amostras de urina, BP.IC - menos bolsas vinculadas
• Assunto(s): Microextração em fase líquida Microextração em fase sólida Cromatografia Cromatografia líquida Espectrometria de massas
• Palavra(s)-Chave do Pesquisador: cromatografia líquida capilar | microextração em fase líquida | Microextração em fase sólida | nanocromatografia líquida (nano-LC) | sistemas multiplexados | sistemas paralelizados | Cromatografia

Resumo

A motivação principal dessa proposta centra-se no reconhecimento de que uma bem explorada associação de micro técnicas cobrindo o preparo da amostras, a cromatografia e a espectrometria de massas exibe potencialidades concretas para ganhos em qualidade analítica em conjunto com um respeito a preceitos da química verde. Assim, de maneira objetiva, são previstos avanços cobrindo desde aspectos fundamentais até aplicações a amostras reais de relevância envolvendo essa associação de micro técnicas de análise. Os seguintes tópicos serão destacados, em busca de uma concreta evolução nas ciências analíticas: i) a pesquisa de novos materiais, meios e estratégias aplicadas ao aumento do desempenho de micro extrações; ii) a inovação na automatização e associação das técnicas analíticas de preparo de amostras, cromatografia e espectrometria de massas; iii) a busca por novas colunas cromatográficas mais eficientes e robustas em micro e nano escalas e (v) a avaliação, desenvolvimento e aplicação do acoplamento das micro e nano colunas desenvolvidas com a espectrometria de massas para maior eficiência de ionização e capacidades de obtenção de níveis de detecção sem precedentes a partir do uso de quantidades limitadas de amostras complexas. No quesito das aplicações em química e áreas relacionadas, enfocaremos: i) aplicações biomédicas para a análise de marcadores endógenos e fármacos/drogas em fluidos biológicos; ii) aplicações ambientais no estudo da degradação de fármacos e outros compostos emergentes em biorreatores; iii) aplicações ecotoxicológicas para monitorar a absorção de toxicantes por pequenos organismos aquáticos, correlacionando a informação química com outras observações toxicológicas; iv) aplicações em segurança alimentar buscando-se métodos mais rápidos, eficientes e robustos para analitos e matrizes que apresentam severas dificuldades analíticas. (AU)

Publicações científicas

(93)

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

CRUZ, JONAS CARNEIRO; DE FARIA, HENRIQUE DIPE; FIGUEIREDO, EDUARDO COSTA; QUEIROZ, MARIA EUGENIA COSTA. Restricted access carbon nanotube for microextraction by packed sorbent to determine antipsychotics in plasma samples by high-performance liquid chromatography-tandem mass spectrometry. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, v. 412, n. 11, SI, FEB 2020. (17/02147-0)

MACIEL, EDVALDO V. S.; BORSATTO, JOAO V. B.; MEJIA-CARMONA, KAREN; LANCAS, FERNANDO M.. Application of an in-house packed octadecylsilica-functionalized graphene oxide column for capillary liquid chromatography analysis of hormones in urine samples. Analytica Chimica Acta, v. 1239, p. 10-pg., 2022-12-20. (17/02147-0)

DA CUNHA, KELLY FRANCISCO; OLIVEIRA, KARINA DINIZ; HUESTIS, MARILYN A.; COSTA, JOSE LUIZ. Screening of 104 New Psychoactive Substances (NPS) and Other Drugs of Abuse in Oral Fluid by LC-MS-MS. JOURNAL OF ANALYTICAL TOXICOLOGY, v. 44, n. 7, p. 697-707, SEP 2020. (17/02147-0, 18/11849-0, 18/00432-1)

RODRIGUEZ CABAL, LUIS FELIPE; VARGAS MEDINA, DEYBER ARLEY; LIMA, ADRIEL MARTINS; LANCAS, FERNANDO MAURO; SANTOS-NETO, ALVARO JOSE. Robotic-assisted dynamic large drop microextraction. Journal of Chromatography A, v. 1608, DEC 20 2019. (17/02147-0, 16/21950-5, 10/19910-9)

ACQUARO JUNIOR, VINICIUS R.; GOMEZ-RIOS, GERMAN AUGUSTO; TASCON, MARCOS; COSTA QUEIROZ, MARIA EUGENIA; PAWLISZYN, JANUSZ. Analysis of endocannabinoids in plasma samples by biocompatible solid-phase microextraction devices coupled to mass spectrometry. Analytica Chimica Acta, v. 1091, p. 135-145, DEC 24 2019. (17/02147-0, 16/16180-6)

DA CUNHA, KELLY FRANCISCO; RODRIGUES, LEONARDO COSTALONGA; HUESTIS, MARILYN A.; COSTA, JOSE LUIZ. Miniaturized extraction method for analysis of synthetic opioids in urine by microextraction with packed sorbent and liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, v. 1624, AUG 2 2020. (17/02147-0, 18/11849-0, 17/24515-0, 18/00432-1)

VASCONCELOS SOARES MACIEL, EDVALDO; MEJIA-CARMONA, KAREN; LANCAS, FERNANDO MAURO. Evaluation of Two Fully Automated Setups for Mycotoxin Analysis Based on Online Extraction-Liquid Chromatography-Tandem Mass Spectrometry. Molecules, v. 25, n. 12, JUN 2020. (17/02147-0, 15/15462-5, 14/07347-9)

DA CUNHA, KELLY FRANCISCO; OLIVEIRA, KARINA DINIZ; CARDOSO, MARILIA SANTORO; FURIOZO ARANTES, ANA CAROLINA; PIRAS COSER, PEDRO HENRIQUE; LIMA, LUCAS DE NORONHA; SAMPAIO MALUF, ANA CRISTHINA; DE CASTRO COMIS, MARIA ANGELICA; HUESTIS, MARILYN A.; COSTA, JOSE LUIZ. Prevalence of new psychoactive substances (NPS) in Brazil based on oral fluid analysis of samples collected at electronic music festivals and parties. DRUG AND ALCOHOL DEPENDENCE, v. 227, OCT 1 2021. (17/02147-0, 18/11849-0, 18/00432-1)

MAGALHAES KAHL, JULIA MARTINELLI; DA CUNHA, KELLY FRANCISCO; RODRIGUES, LEONARDO COSTALONGA; CHINAGLIA, KAUE DE OLIVEIRA; OLIVEIRA, KARINA DINIZ; COSTA, JOSE LUIZ. Quantification of amphetamine and derivatives in oral fluid by dispersive liquid-liquid microextraction and liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, v. 196, MAR 20 2021. (17/02147-0, 18/00432-1)

VARGAS MEDINA, DEYBER ARLEY; SOARES MACIEL, EDVALDO VASCONCELOS; DE TOFFOLI, ANA LUCIA; LANCAS, FERNANDO MAURO. Miniaturization of liquid chromatography coupled to mass spectrometry. 2. Achievements on modern instrumentation for miniaturized liquid chromatography coupled to mass spectrometry. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 128, JUL 2020. (17/02147-0, 15/15462-5, 14/07347-9, 19/22724-7)

VARGAS MEDINA, DEYBER ARLEY; PEREIRA DOS SANTOS, NATALIA GABRIELLY; DA SILVA BURATO, JULIANA SOARES; BASOLLI BORSATTO, JOAO VICTOR; LANCAS, FERNANDO MAURO. An overview of open tubular liquid chromatography with a focus on the coupling with mass spectrometry for the analysis of small molecules. Journal of Chromatography A, v. 1641, MAR 29 2021. (19/26263-4, 19/22724-7, 14/07347-9, 17/02147-0, 14/03765-0, 15/15462-5)

DE CAMPOS, VICTORIA M.; ANDRADE, MARIANE A.; MACIEL, EDVALDO V. S.; DE TOFFOLI, ANA LUCIA; LANCAS, FERNANDO M.. Environmentally friendly analysis of sulphonamides in Brazilian honey through automated and miniaturised sample preparation coupled with LC-MS/MS. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure, v. 39, n. 5, p. 13-pg., 2022-03-25. (17/02147-0)

MARCHIONI, CAMILA; DE SOUZA, ISRAEL DONIZETI; ACQUARO JUNIOR, VINICIUS RICARDO; DE SOUZA CRIPPA, JOSE ALEXANDRE; TUMAS, VITOR; COSTA QUEIROZ, MARIA EUGENIA. Recent advances in LC-MS/MS methods to determine endocannabinoids in biological samples: Application in neurodegenerative diseases. Analytica Chimica Acta, v. 1044, p. 12-28, DEC 31 2018. (17/02147-0, 15/07619-1, 16/13639-8)

GRECCO, CAROLINE F.; SOUZA, ISRAEL D.; ACQUARO JUNIOR, VINICIUS R.; QUEIROZ, MARIA E. C.. Determination of Parabens in Breast Milk Samples by Dispersive Liquid-Liquid Microextraction (DLLME) and Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry. Journal of the Brazilian Chemical Society, v. 30, n. 1, p. 48-59, JAN 2019. (17/02147-0, 15/04060-3, 15/07619-1)

VARGAS MEDINA, DEYBER ARLEY; SANTOS-NETO, ALVARO JOSE; CERDA, VICTOR; MAYA, FERNANDO. Automated dispersive liquid-liquid microextraction based on the solidification of the organic phase. Talanta, v. 189, p. 241-248, NOV 1 2018. (17/02147-0, 10/19910-9, 16/21950-5)

CARNEIRO, JUSSARA F.; SILVA, FERNANDO L.; MARTINS, ALYSSON S.; DIAS, RAFAEL M. P.; TITATO, GUILHERME M.; SANTOS-NETO, ALVARO J.; BERTAZZOLI, RODNEI; LANZA, MARCOS R. V.. Simultaneous degradation of hexazinone and diuron using ZrO2-nanostructured gas diffusion electrode. CHEMICAL ENGINEERING JOURNAL, v. 351, p. 650-659, NOV 1 2018. (17/10118-0, 14/50945-4, 17/02147-0, 04/09498-2, 16/01937-4, 11/14314-1)

DA SILVA BURATO, JULIANA SOARES; VARGAS MEDINA, DEYBER ARLEY; DE TOFFOLI, ANA LUCIA; SOARES MACIEL, EDVALDO VASCONCELOS; LANCAS, FERNANDO MAURO. Recent advances and trends in miniaturized sample preparation techniques. JOURNAL OF SEPARATION SCIENCE, v. 43, n. 1, SI, p. 202-225, JAN 2020. (17/02147-0, 15/15462-5, 14/07347-9)

MEJIA-CARMONA, KAREN; DA SILVA BURATO, JULIANA SOARES; BASOLLI BORSATTO, JOAO VICTOR; DE TOFFOLI, ANA LUCIA; LACAS, FERNANDO MAURO. Miniaturization of liquid chromatography coupled to mass spectrometry 1. Current trends on miniaturized LC columns. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 122, JAN 2020. (17/02147-0, 15/15462-5, 14/07347-9)

SARTORE, DOUGLAS MORISUE; VARGAS MEDINA, DEYBER ARLEY; COSTA, JOSE LUIZ; LANCAS, FERNANDO MAURO; SANTOS-NETO, ALVARO JOSE. Automated microextraction by packed sorbent of cannabinoids from human urine using a lab-made device packed with molecularly imprinted polymer. Talanta, v. 219, NOV 1 2020. (17/02147-0, 19/22724-7, 10/19910-9)

AKAMINE, LIDIA AKEMI; MEDINA, DEYBER ARLEY VARGAS; LANCAS, FERNANDO MAURO. Magnetic solid-phase extraction of gingerols in ginger containing products. Talanta, v. 222, JAN 15 2021. (17/02147-0, 10/19910-9, 19/22724-7)

DA SILVA, LUIS FELIPE; VARGAS MEDINA, DEYBER ARLEY; LANCAS, FERNANDO MAURO. Automated needle-sleeve based online hyphenation of solid-phase microextraction and liquid chromatography. Talanta, v. 221, JAN 1 2021. (14/07347-9, 14/03765-0, 15/15462-5, 17/02147-0, 19/22724-7)

DE TOFFOLI, ANA LUCIA; SOARES MACIEL, EDVALDO VASCONCELOS; LANCAS, FERNANDO MAURO. Evaluation of the tubing material and physical dimensions on the performance of extraction columns for on-line sample preparation-LC-MS/MS. Journal of Chromatography A, v. 1597, p. 18-27, JUL 19 2019. (17/02147-0, 15/15462-5, 14/07347-9)

FRANCO, MARAISSA S.; PADOVAN, RODRIGO N.; FUMES, BRUNO H.; PALMER, CHRISTOPHER P.; MCGETTRICK, JULIE R.; LANCAS, FERNANDO M.. Silica modified with polymeric amphiphilic nanoparticles as first dimension for multidimensional separation techniques. Journal of Chromatography A, v. 1597, p. 149-158, JUL 19 2019. (17/02147-0, 15/15462-5, 14/07347-9, 15/03998-8)

MEJIA-CARMONA, KAREN; JORDAN-SINISTERRA, MARCELA; LANCAS, FERNANDO M.. Current Trends in Fully Automated On-Line Analytical Techniques for Beverage Analysis. BEVERAGES, v. 5, n. 1, MAR 2019. (17/02147-0, 15/15462-5, 14/07347-9)

GRECCO, CAROLINE FERNANDES; SOUZA, ISRAEL D.; COSTA QUEIROZ, MARIA EUGENIA. Recent development of chromatographic methods to determine parabens in breast milk samples: A review. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, v. 1093, p. 82-90, SEP 1 2018. (17/03726-3, 17/02147-0)

SOARES MACIEL, EDVALDO VASCONCELOS; DE TOFFOLI, ANA LUCIA; ALVES, JUSSARA DA SILVA; LANCAS, FERNANDO MAURO. Multidimensional Liquid Chromatography Employing a Graphene Oxide Capillary Column as the First Dimension: Determination of Antidepressant and Antiepileptic Drugs in Urine. Molecules, v. 25, n. 5, MAR 1 2020. (17/02147-0, 15/15462-5, 14/07347-9)

BORSATTO, JOAO V. B.; MACIEL, EDVALDO V. S.; CIFUENTES, ALEJANDRO; LANCAS, FERNANDO M.. Online Extraction Followed by LC-MS/MS Analysis of Lipids in Natural Samples: A Proof-of-Concept Profiling Lecithin in Seeds. FOODS, v. 12, n. 2, p. 12-pg., 2023-01-01. (17/02147-0, 19/22724-7)

COSTA QUEIROZ, MARIA EUGENIA; DE SOUZA, ISRAEL DONIZETI; MARCHIONI, CAMILA. Current advances and applications of in-tube solid-phase microextraction. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 111, p. 261-278, FEB 2019. (17/02147-0)

QUEIROZ, MARIA EUGENIA C.; LEMOS PINTO, MONIA AP; CRUZ, JONAS CARNEIRO; USHIROHIRA, JULIANA MAYUMI; DA SILVA DIAS, ISABELLA CAROLINE; HALLAK, JAIME E. C.. Schizophrenia: recent advances in LC-MS/MS methods to determine antipsychotic drugs in biological samples. BIOANALYSIS, v. 11, n. 3, p. 215-231, FEB 2019. (17/02147-0)

VARGAS MEDINA, DEYBER ARLEY; SOARES MACIEL, EDVALDO VASCONCELOS; LANCAS, FERNANDO MAURO. Miniaturization of liquid chromatography coupled to mass spectrometry. 3. Achievements on chip-based LC-MS devices. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 131, OCT 2020. (19/22724-7, 14/03765-0, 15/15462-5, 17/02147-0, 14/07347-9)

CARVALHO OLIVEIRA, IGOR GUSTAVO; COSTA QUEIROZ, MARIA EUGENIA. A micro salting-out assisted liquid-liquid extraction combined with ultra-high performance liquid chromatography tandem mass spectrometry to determine anandamide and 2-arachidonoylglycerol in rat brain samples. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, v. 1158, NOV 20 2020. (14/50891-1, 17/02147-0)

SOARES MACIEL, EDVALDO VASCONCELOS; LANCAS, FERNANDO MAURO. cartridge-based device for automated analyses of solid matrices by online sample prep-capillary LC-MS/M. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, v. 414, n. 8, SI, p. 2725-2737, MAR 2022. (17/02147-0)

CRUZ, JONAS CARNEIRO; CABRAL MIRANDA, LUIS FELIPPE; COSTA QUEIROZ, MARIA EUGENIA. Pipette tip micro-solid phase extraction (octyl-functionalized hybrid silica monolith) and ultra-high-performance liquid chromatography-tandem mass spectrometry to determine cannabidiol and tetrahydrocannabinol in plasma samples. JOURNAL OF SEPARATION SCIENCE, v. 44, n. 8, JAN 2021. (17/02147-0)

SOARES MACIEL, EDVALDO VASCONCELOS; PEREIRA DOS SANTOS, NATALIA GABRIELLY; VARGAS MEDINA, DEYBER ARLEY; LANCAS, FERNANDO MAURO. Electron ionization mass spectrometry: Quo vadis?. ELECTROPHORESIS, v. 43, n. 15, p. 14-pg., 2022-05-20. (19/26263-4, 19/22724-7, 17/02147-0, 14/03765-0, 15/15462-5, 14/07347-9)

DOS SANTOS, NATALIA GABRIELLY; MEDINA, DEYBER ARLEY VARGAS; LANCAS, FERNANDO MAURO. Microextraction by packed sorbent of N-nitrosamines from Losartan tablets using a high-throughput robot platform followed by liquid chromatography-tandem mass spectrometry. JOURNAL OF SEPARATION SCIENCE, v. 46, n. 17, p. 13-pg., 2023-07-03. (15/15462-5, 19/22724-7, 17/02147-0, 14/07347-9, 19/26263-4)

DOS SANTOS, NATALIA GABRIELLY PEREIRA; MACIEL, EDVALDO VASCONCELOS SOARES; MEDINA, DEYBER ARLEY VARGAS; LANCAS, FERNANDO MAURO. NanoLC-EI-MS: Perspectives in Biochemical Analysis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 24, n. 14, p. 14-pg., 2023-07-01. (19/22724-7, 17/21984-0, 17/02147-0, 17/21985-6, 19/26263-4)

GRECCO, CAROLINE FERNANDES; TUMAS, VITOR; HALLAK, JAIME EDUARDO CECILIO; QUEIROZ, MARIA EUGENIA COSTA. In-tube solid-phase microextraction (sulfopropyl methacrylate-co-ethylene glycol dimethacrylate monolithic capillary) coupled to LC-MS/MS to determine beta amyloid peptides in Alzheimer's cerebrospinal fluid samples. SEPARATION SCIENCE PLUS, v. N/A, p. 12-pg., 2023-08-07. (17/02147-0, 20/00126-8, 19/04386-7)

ANDRADE, FELIPE N.; SANTOS-NETO, ALVARO JOSE; MEDINA, DEYBER ARLEY V.; LANCAS, FERNANDO M.. A molecularly imprinted polymer for microextraction by packed sorbent of sulfonylureas herbicides from corn samples. Journal of Food Composition and Analysis, v. 121, p. 7-pg., 2023-05-12. (15/15462-5, 11/09898-4, 19/22724-7, 17/02147-0, 14/07347-9, 13/17425-4)

GRECCO, CAROLINE FERNANDES; DE SOUZA, ISRAEL DONIZETI; OLIVEIRA, IGOR GUSTAVO CARVALHO; QUEIROZ, MARIA EUGENIA COSTA. In-Tube Solid-Phase Microextraction Directly Coupled to Mass Spectrometric Systems: A Review. SEPARATIONS, v. 9, n. 12, p. 19-pg., 2022-12-01. (17/02147-0, 19/19485-0, 20/00126-8, 20/06526-8, 19/04386-7)

OLIVEIRA, THAIS CAMAROTTO; LANCAS, FERNANDO MAURO. Determination of selected herbicides employed in sugarcane crops by disposable pipette tip (DPX) extraction followed by LC-MS/MS and GC-MS/MS. Journal of Liquid Chromatography & Related Technologies, v. 44, n. 17-20, p. 8-pg., 2022-08-22. (17/02147-0, 14/07347-9, 19/22724-7, 15/15462-5)

DA SILVA BURATO, JULIANA SOARES; BASOLLI BORSATTO, JOAO VICTOR; LANCAS, FERNANDO MAURO. Practical aspects of preparation, optimization, and evaluation of poly (styrene-divinylbenzene)porous-layer open tubular (PLOT) columns for capillary liquid chromatography. Talanta, v. 253, p. 7-pg., 2023-02-01. (17/02147-0, 14/07347-9, 19/22724-7, 15/15462-5)

BORSATTO, JOAO V. B.; LANCAS, FERNANDO M. M.. Recent Trends in Graphene-Based Sorbents for LC Analysis of Food and Environmental Water Samples. Molecules, v. 28, n. 13, p. 21-pg., 2023-07-01. (17/02147-0, 19/22724-7)

DA CUNHA, KELLY FRANCISCO; LANARO, RAFAEL; MARTINS, ALINE FRANCO; OLIVEIRA, KARINA DINIZ; COSTA, JOSE LUIZ. Use of injection-port derivatization for the analysis of cocaine and its metabolites in urine by gas chromatography-tandem mass spectrometry. Forensic Toxicology, v. 39, n. 1, p. 8-pg., 2020-08-01. (17/02147-0, 18/11849-0, 18/00432-1)

CAROLINE F. GRECCO; EDUARDO JOSÉ CREVELIN; VITOR TUMAS; JAIME EDUARDO C. HALLAK; MARIA EUGÊNIA C. QUEIROZ. Disposable Pipette Extraction Followed by Direct MS/MS Analysis of Beta Amyloid Peptides (Aß38, Aß40, and Aβ42) in Cerebrospinal Fluid Samples. Journal of the Brazilian Chemical Society, v. 36, n. 1, 2024-06-17. (17/02147-0, 20/00126-8, 19/04386-7)

MEDINA, DEYBER ARLEY VARGAS; MACIEL, EDVALDO VASCONCELOS SOARES; DOS SANTOS, NATALIA GABRIELLY PEREIRA; LANCAS, FERNANDO MAURO. The overshadowed role of electron ionization-mass spectrometry in analytical biotechnology. CURRENT OPINION IN BIOTECHNOLOGY, v. 82, p. 9-pg., 2023-06-30. (17/02147-0, 19/22724-7)

VARGAS MEDINA, DEYBER ARLEY; RODRIGUEZ CABAL, LUIS FELIPE; LANCAS, FERNANDO MAURO; SANTOS-NETO, ALVARO JOSE. Sample treatment platform for automated integration of microextraction techniques and liquid chromatography analysis. HARDWAREX, v. 5, p. 16-pg., 2019-04-01. (17/02147-0, 10/19910-9, 14/03765-0)

DA SILVA BURATO, JULIANA SOARES; VARGAS MEDINA, DEYBER ARLEY; DE TOFFOLI, ANA LUCIA; SOARES MACIEL, EDVALDO VASCONCELOS; LANCAS, FERNANDO MAURO. Recent advances and trends in miniaturized sample preparation techniques. JOURNAL OF SEPARATION SCIENCE, v. 43, n. 1, p. 24-pg., 2019-12-23. (17/02147-0, 15/15462-5, 14/07347-9)

CRUZ, JONAS CARNEIRO; DE FARIA, HENRIQUE DIPE; FIGUEIREDO, EDUARDO COSTA; QUEIROZ, MARIA EUGENIA COSTA. Restricted access carbon nanotube for microextraction by packed sorbent to determine antipsychotics in plasma samples by high-performance liquid chromatography-tandem mass spectrometry. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, v. 412, n. 11, p. 11-pg., 2020-02-05. (17/02147-0)

DA CUNHA, KELLY FRANCISCO; LANARO, RAFAEL; MARTINS, ALINE FRANCO; OLIVEIRA, KARINA DINIZ; COSTA, JOSE LUIZ. Use of injection-port derivatization for the analysis of cocaine and its metabolites in urine by gas chromatography-tandem mass spectrometry. Forensic Toxicology, AUG 2020. (17/02147-0, 18/00432-1, 18/11849-0)

MEJIA-CARMONA, KAREN; MACIEL, EDVALDO VASCONCELOS SOARES; LANCAS, FERNANDO MAURO. Miniaturized liquid chromatography applied to the analysis of residues and contaminants in food: A review. ELECTROPHORESIS, v. 41, n. 20, SI, MAY 2020. (17/02147-0, 15/15462-5, 14/07347-9)

DA SILVA BURATO, JULIANA SOARES; VARGAS MEDINA, DEYBER ARLEY; DE TOFFOLI, ANA LUCIA; SOARES MACIEL, EDVALDO VASCONCELOS; LANCAS, FERNANDO MAURO. Recent advances and trends in miniaturized sample preparation techniques. JOURNAL OF SEPARATION SCIENCE, v. 43, n. 1, SI, DEC 2019. (17/02147-0, 15/15462-5, 14/07347-9)

SOUZA, ISRAEL D.; OLIVEIRA, IGOR G. C.; QUEIROZ, MARIA EUGENIA C.. Innovative extraction materials for fiber-in-tube solid phase microextraction: A review. Analytica Chimica Acta, v. 1165, JUN 22 2021. (20/00126-8, 18/06068-0, 17/02147-0, 19/19485-0)

DA SILVA, LUIS FELIPE; LANCAS, FERNANDO MAURO. beta-Cyclodextrin coupled to graphene oxide supported on aminopropyl silica as a sorbent material for determination of isoflavones. JOURNAL OF SEPARATION SCIENCE, v. 43, n. 23, OCT 2020. (17/02147-0)

VARGAS MEDINA, DEYBER ARLEY; RODRIGUEZ CABAL, LUIS FELIPE; TITATO, GUILHERME MIOLA; LANCAS, FERNANDO MAURO; SANTOS-NETO, ALVARO JOSE. Automated online coupling of robot-assisted single drop microextraction and liquid chromatography. Journal of Chromatography A, v. 1595, p. 66-72, JUN 21 2019. (17/02147-0, 10/19910-9, 16/21950-5)

MARCHIONI, CAMILA; VIEIRA, TATIANA MANZINI; MILLER CROTTI, ANTONIO EDUARDO; CRIPPA, JOSE ALEXANDRE; COSTA QUEIROZ, MARIA EUGENIA. In-tube solid-phase microextraction with a dummy molecularly imprinted monolithic capillary coupled to ultra-performance liquid chromatography-tandem mass spectrometry to determine cannabinoids in plasma samples. Analytica Chimica Acta, v. 1099, p. 145-154, FEB 22 2020. (17/02147-0, 16/13639-8)

MIRANDA, LUIS F. C.; GONCALVES, ROGERIA R.; QUEIROZ, MARIA E. C.. A Dual Ligand Sol-Gel Organic-Silica Hybrid Monolithic Capillary for In-Tube SPME-MS/MS to Determine Amino Acids in Plasma Samples. Molecules, v. 24, n. 9, MAY 1 2019. (17/02147-0)

SOUZA, ISRAEL D.; ANDERSON, JARED L.; QUEIROZ, MARIA EUGENIA C.. Crosslinked zwitterionic polymeric ionic liquid-functionalized nitinol wires for fiber-in-tube solid-phase microextraction and UHPLC-MS/MS as an amyloid beta peptide binding protein assay in biological fluids. Analytica Chimica Acta, v. 1193, FEB 8 2022. (17/02147-0, 19/19485-0, 20/00126-8)

CRUZ, JONAS CARNEIRO; DE SOUZA, ISRAEL DONIZETI; GRECCO, CAROLINE FERNANDES; FIGUEIREDO, EDUARDO COSTA; QUEIROZ, MARIA EUGENIA COSTA. Recent advances in column switching high-performance liquid chromatography for bioanalysis. SUSTAINABLE CHEMISTRY AND PHARMACY, v. 21, JUN 2021. (19/19485-0, 19/04386-7, 20/00126-8, 17/02147-0)

MACIEL, EDVALDO VASCONCELOS SOARES; MEDINA, DEYBER ARLEY VARGAS; BORSATTO, JOAO VICTOR BASSOLLI; LANCAS, FERNANDO MAURO. Towards a universal automated and miniaturized sample preparation approach. SUSTAINABLE CHEMISTRY AND PHARMACY, v. 21, JUN 2021. (17/02147-0, 14/03765-0, 19/22724-7, 14/07347-9)

SOARES MACIEL, EDVALDO VASCONCELOS; DE TOFFOLI, ANA LUCIA; SOBIESKI, EDUARDO; DOMINGUES NAZARIO, CARLOS EDUARDO; LANCAS, FERNANDO MAURO. Miniaturized liquid chromatography focusing on analytical columns and mass spectrometry: A review. Analytica Chimica Acta, v. 1103, p. 11-31, MAR 22 2020. (17/02147-0, 15/15462-5, 14/07347-9)

SOUZA, ISRAEL D.; HANTAO, LEANDRO W.; QUEIROZ, MARIA EUGENIA C.. Polymeric ionic liquid open tubular capillary column for on-line in-tube SPME coupled with UHPLC-MS/MS to determine endocannabinoids in plasma samples. Analytica Chimica Acta, v. 1045, p. 108-116, JAN 3 2019. (17/02147-0, 16/01082-9, 15/07619-1)

MEDINA, DEYBER ARLEY VARGAS; BORSATTO, JOAO VICTOR BASSOLLI; MACIEL, EDVALDO VASCONCELOS SOARES; LANCAS, FERNANDO MAURO. Current role of modern chromatography and mass spectrometry in the analysis of mycotoxins in food. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 135, FEB 2021. (17/02147-0, 15/15462-5, 14/07347-9)

RODRIGUEZ CABAL, LUIS FELIPE; VARGAS MEDINA, DEYBER ARLEY; COSTA, JOSE LUIZ; LANCAS, FERNANDO MAURO; SANTOS-NETO, ALVARO JOSE. Determination of ring-substituted amphetamines through automated online hollow fiber liquid-phase microextraction-liquid chromatography. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, v. 411, n. 29, p. 7889-7897, NOV 2019. (17/02147-0, 18/00432-1, 16/21950-5, 10/19910-9)

COSTA QUEIROZ, MARIA EUGENIA; DE SOUZA, ISRAEL DONIZETI; DE OLIVEIRA, IGOR GUSTAVO; GRECCO, CAROLINE FERNANDES. In vivo solid phase microextraction for bioanalysis. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 153, p. 18-pg., 2022-05-04. (20/06526-8, 17/02147-0, 19/04386-7, 19/19485-0, 20/00126-8)

SOARES MACIEL, EDVALDO VASCONCELOS; DE TOFFOLI, ANA LUCIA; SOBIESKI NETO, EDUARDO; DOMINGUES NAZARIO, CARLOS EDUARDO; LANCAS, FERNANDO MAURO. New materials in sample preparation: Recent advances and future trends. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 119, OCT 2019. (17/02147-0, 15/15462-5, 14/07347-9)

DE CARVALHO OLIVEIRA, IGOR GUSTAVO; MARCHIONI, CAMILA; COSTA QUEIROZ, MARIA EUGENIA. Determination of anandamide in cerebrospinal fluid samples by disposable pipette extraction and ultra-high performance liquid chromatography tandem mass spectrometry. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, v. 1130, NOV 1 2019. (17/02147-0)

MEJIA-CARMONA, KAREN; LANCAS, FERNANDO M.. Modified graphene-silica as a sorbent for in-tube solid-phase microextraction coupled to liquid chromatography-tandem mass spectrometry. Determination of xanthines in coffee beverages. Journal of Chromatography A, v. 1621, JUN 21 2020. (17/02147-0, 15/15462-5, 14/07347-9)

JORDAN-SINISTERRA, MARCELA; VARGAS MEDINA, DEYBER ARLEY; LANCAS, FERNANDO MAURO. Microextraction by packed sorbent of polycyclic aromatic hydrocarbons in brewed coffee samples with a new zwitterionic ionic liquid-modified silica sorbent. Journal of Food Composition and Analysis, v. 114, p. 9-pg., 2022-08-27. (14/07347-9, 19/22724-7, 17/02147-0, 15/15462-5)

SOARES MACIEL, EDVALDO VASCONCELOS; DE TOFFOLI, ANA LUCIA; LANCAS, FERNANDO MAURO. Current status and future trends on automated multidimensional separation techniques employing sorbent-based extraction columns. JOURNAL OF SEPARATION SCIENCE, v. 42, n. 1, p. 258-272, JAN 2019. (14/07347-9, 17/02147-0, 15/15462-5)

BELOTI, LUIZ G. M.; MIRANDA, LUIS F. C.; QUEIROZ, MARIA EUGENIA C.. Butyl Methacrylate-Co-Ethylene Glycol Dimethacrylate Monolith for Online in-Tube SPME-UHPLC-MS/MS to Determine Chlopromazine, Clozapine, Quetiapine, Olanzapine, and Their Metabolites in Plasma Samples. Molecules, v. 24, n. 2, JAN 2 2019. (17/02147-0)

MEDINA, V, DEYBER A.; FIGUEROLA, ANDREU; RODRIGUEZ, FELIPE; SANTOS-NETO, ALVARO J.; CABELLO, CARLOS P.; PALOMINO, GEMMA T.; CERDA, VICTOR; MAYA, FERNANDO. Hyperporous carbon-coated 3D printed devices. APPLIED MATERIALS TODAY, v. 14, p. 29-34, MAR 2019. (17/02147-0, 10/19910-9)

MACIEL, EDVALDO VASCONCELOS SOARES; MEJIA-CARMONA, KAREN; JORDAN-SINISTERRA, MARCELA; DA SILVA, LUIS FELIPE; VARGAS MEDINA, DEYBER ARLEY; LANCAS, FERNANDO MAURO. The Current Role of Graphene-Based Nanomaterials in the Sample Preparation Arena. FRONTIERS IN CHEMISTRY, v. 8, AUG 11 2020. (17/02147-0, 15/15462-5, 14/07347-9)

GRECCO, CAROLINE FERNANDES; MIRANDA, LUIS FELIPPE CABRAL; QUEIROZ, MARIA EUGENIA COSTA. Aminopropyl hybrid silica monolithic capillary containing mesoporous SBA-15 particles for in-tube SPME-HILIC-MS/MS to determine levodopa, carbidopa, benserazide, dopamine, and 3-O-methyldopa in plasma samples. Microchemical Journal, v. 157, SEP 2020. (17/02147-0, 17/03726-3)

SARTORE, DOUGLAS M.; MEDINA, DEYBER VARGAS A.; BOCELLI, MARCIO D.; JORDAN-SINISTERRA, MARCELA; SANTOS-NETO, ALVARO J.; LANCAS, FERNANDO M.. Modern automated microextraction procedures for bioanalytical, environmental, and food analyses. JOURNAL OF SEPARATION SCIENCE, v. 46, n. 15, p. 30-pg., 2023-05-26. (17/02147-0, 19/22724-7, 15/15462-5, 14/07347-9)

BOCELLI, MARCIO DAVID; MEDINA, DEYBER ARLEY VARGAS; LANCAS, FERNANDO MAURO; DOS SANTOS-NETO, ALVARO JOSE. Automated microextraction by packed sorbent of endocrine disruptors in wastewater using a high-throughput robotic platform followed by liquid chromatography-tandem mass spectrometry. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, v. N/A, p. 12-pg., 2023-08-03. (17/02147-0, 19/22724-7, 15/15462-5, 14/07347-9)

MEDINA, DEYBER ARLEY VARGAS; MACIEL, EDVALDO VASCONCELOS SOARES; LANCAS, FERNANDO MAURO. Modern automated sample preparation for the determination of organic compounds: A review on robotic and on-flow systems. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 166, p. 21-pg., 2023-09-01. (17/02147-0, 19/22724-7, 17/21984-0, 17/21985-6)

MEDINA, DEYBER ARLEY VARGAS; CARDOSO, ALESSANDRA TIMOTEO; BORSATTO, JOAO VICTOR BASOLLI; LANCAS, FERNANDO MAURO. Open tubular liquid chromatography: Recent advances and future trends. JOURNAL OF SEPARATION SCIENCE, v. N/A, p. 22-pg., 2023-08-15. (17/02147-0, 19/22724-7)

DE SOUZA, ISRAEL DONIZETI; QUEIROZ, MARIA EUGENIA COSTA. Advances in sample preparation and HPLC-MS/MS methods for determining amyloid-beta peptide in biological samples: a review. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, v. 415, n. 18, p. 19-pg., 2023-03-06. (17/02147-0, 19/19485-0, 20/00126-8)

VARGAS MEDINA, DEYBER ARLEY; PEREIRA DOS SANTOS, NATALIA GABRIELLY; SOARES MACIEL, EDVALDO VASCONCELOS; LANCAS, FERNANDO MAURO. Current prospects on nano liquid chromatography coupled to electron ionization mass spectrometry (nanoLC-EI-MS). Journal of Liquid Chromatography & Related Technologies, v. 44, n. 17-20, p. 10-pg., 2022-08-17. (19/26263-4, 19/22724-7, 17/02147-0, 14/03765-0, 15/15462-5, 14/07347-9)

SOUZA, ISRAEL D.; ANDERSON, JARED L.; TUMAS, VITOR; QUEIROZ, MARIA EUGENIA C.. Direct coupling of fiber-in-tube solid-phase microextraction with tandem mass spectrometry to determine amyloid beta peptides as biomarkers for Alzheimer's disease in cerebrospinal fluid samples. Talanta, v. 254, p. 8-pg., 2023-03-01. (19/19485-0, 20/00126-8, 17/02147-0)

GRECCO, CAROLINE FERNANDES; DE SOUZA, ISRAEL DONIZETI; QUEIROZ, MARIA EUGENIA COSTA. Novel materials as capillary coatings for in-tube solid-phase microextraction for bioanalysis. JOURNAL OF SEPARATION SCIENCE, v. 44, n. 8, p. 1662-1693, APR 2021. (17/02147-0, 20/00126-8, 19/04386-7, 19/19485-0)

CRUZ, JONAS CARNEIRO; DE SOUZA, ISRAEL DONIZETI; LANCAS, FERNANDO MAURO; COSTA QUEIROZ, MARIA EUGENIA. Current advances and applications of online sample preparation techniques for miniaturized liquid chromatography systems. Journal of Chromatography A, v. 1668, p. 16-pg., 2022-04-12. (19/19485-0, 17/02147-0, 20/00126-8)

OLIVEIRA, THAIS CAMAROTTO; LANCAS, FERNANDO MAURO. Determination of selected herbicides in sugarcane-derived foods by graphene-oxide based disposable pipette extraction followed by liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, v. 1687, p. 11-pg., 2023-01-04. (17/02147-0, 19/22724-7, 14/07347-9, 15/15462-5)

BORSATTO, JOAO V. B.; MACIEL, EDVALDO V. S.; LANCAS, FERNANDO M.. Investigation of the applicability of silica-graphene hybrid materials as stationary phases for capillary liquid chromatography. Journal of Chromatography A, v. 1685, p. 8-pg., 2022-11-04. (17/02147-0, 19/22724-7, 14/07347-9, 15/15462-5)

MEDINA, DEYBER ARLEY VARGAS; CARDOSO, ALESSANDRA TIMOTEO; MACIEL, EDVALDO VASCONCELOS SOARES; LANCAS, FERNANDO M.. Current materials for miniaturized sample preparation: Recent advances and future trends. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 165, p. 26-pg., 2023-06-09. (17/02147-0, 19/22724-7, 17/21984-0, 17/21985-6)

BORSATTO, JOAO VICTOR BASOLLI; MACIEL, EDVALDO VASCONCELOS SOARES; CIFUENTES, ALEJANDRO; LANCAS, FERNANDO MAURO. Applicability and Limitations of a Capillary-LC Column-Switching System Using Hybrid Graphene-Based Stationary Phases. Molecules, v. 28, n. 13, p. 14-pg., 2023-07-01. (17/02147-0, 19/22724-7)

SANTOS, NATALIA G. P.; MEDINA, DEYBER A. V.; LANCAS, FERNANDO M.. Development of Wall-Coated Open Tubular Columns and Their Application to Nano Liquid Chromatography Coupled to Tandem Mass Spectrometry. Molecules, v. 28, n. 13, p. 15-pg., 2023-07-01. (15/15462-5, 19/22724-7, 17/02147-0, 14/07347-9, 19/26263-4)

DA CUNHA, KELLY FRANCISCO; OLIVEIRA, KARINA DINIZ; COSTA, JOSE LUIZ. Green analytical toxicology method for determination of synthetic cathinones in oral fluid samples by microextraction by packed sorbent and liquid chromatography-tandem mass spectrometry. Forensic Toxicology, v. N/A, p. 13-pg., 2023-07-28. (17/02147-0, 20/10809-5, 18/11849-0, 18/00432-1)

PINTO, MANIA A. L.; DE SOUZA, ISRAEL D.; MIRANDA, LUIS FELIPPE C.; QUEIROZ, MARIA EUGENIA C.. A New Molecularly Imprinted Polymer for In-Tube SPME/UHPLC-MS/MS of Anandamide in Plasma Samples. Journal of the Brazilian Chemical Society, v. N/A, p. 9-pg., 2023-05-16. (13/03808-9, 15/07619-1, 17/02147-0, 20/00126-8, 19/19485-0)

MEJIA-CARMONA, KAREN; MACIEL, EDVALDO VASCONCELOS SOARES; LANCAS, FERNANDO MAURO. Miniaturized liquid chromatography applied to the analysis of residues and contaminants in food: A review. ELECTROPHORESIS, v. 41, n. 20, p. 14-pg., 2020-05-17. (17/02147-0, 15/15462-5, 14/07347-9)

SARTORE, DOUGLAS MORISUE; COSTA, JOSE LUIZ; LANCAS, FERNANDO MAURO; SANTOS-NETO, ALVARO JOSE. Packed in-tube SPME-LC-MS/MS for fast and straightforward analysis of cannabinoids and metabolites in human urine. ELECTROPHORESIS, v. 43, n. 15, p. 12-pg., 2022-04-29. (17/02147-0)

BOCELLI, MARCIO DAVID; VARGAS MEDINA, DEYBER ARLEY; GARCIA RODRIGUEZ, JULIE PAULIN; LANCAS, FERNANDO MAURO; SANTOS-NETO, ALVARO JOSE. Determination of parabens in wastewater samples via robot-assisted dynamic single-drop microextraction and liquid chromatography-tandem mass spectrometry. ELECTROPHORESIS, v. 43, n. 15, p. 10-pg., 2022-05-26. (17/02147-0, 19/22724-7, 14/07347-9, 15/15462-5)

MEDINA, DEYBER ARLEY VARGAS; BURATO, JULIANA SOARES DA SILVA; BORSATTO, JOAO VICTOR BASOLLI; LANCAS, FERNANDO MAURO. Porous layer open tubular nano liquid chromatography directly coupled to electron ionization mass spectrometry. Journal of Chromatography A, v. 1674, p. 9-pg., 2022-05-16. (17/02147-0, 19/22724-7, 14/07347-9, 15/15462-5)