The use of modern autopsy techniques to investigate human diseases (MODAU)

• Grant number: 13/21728-2
• Support Opportunities: Research Projects - Thematic Grants
• Duration: November 01, 2014 - October 31, 2019
• Field of knowledge: Health Sciences - Medicine - Pathological Anatomy and Clinical Pathology
• Principal Investigator: Paulo Hilário Nascimento Saldiva
• Grantee: Paulo Hilário Nascimento Saldiva
• Host Institution: Instituto de Estudos Avançados (IEA). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Pesquisadores principais:( Últimos ): Carlos Augusto Gonçalves Pasqualucci ; Edson Amaro Junior ; Elaine Maria Frade Costa ; Gregório Cardoso Tápias Ceccantini ; Julio da Motta Singer ; Ligia Vizeu Barrozo ; Luiz Fernando Ferraz da Silva ; Marcos Silveira Buckeridge ; Marisa Dolhnikoff ; Mitiko Saiki ; Pérola de Castro Vasconcellos ; Thais Mauad
• Pesquisadores principais:( Antigos ): João Eduardo Ferreira ; Maria de Fátima Andrade
• Associated researchers: Alexandre Valotta da Silva ; Aline Pivetta Cora ; Ana Luiza de Souza Bierrenbach ; Ana Paula Cremasco Takano ; Antonio Carlos Pedroso de Lima ; Carmen Diva Saldiva de André ; Catia Martinez Minto ; Claudia da Costa Leite ; Claudia Kimie Suemoto ; Gisela Tunes da Silva ; Henrique César Santejo Silveira ; José Marcelo Farfel ; lea tenenholz grinberg ; Leila Antonangelo ; Lucia Maria Machado Bógus ; Lucia Pereira Barroso ; Luiz Alberto Amador Pereira ; Maria de Fátima Andrade ; Maria Lucia Bueno Garcia ; Mariana Matera Veras ; Marina Jorge de Miranda ; Milton de Arruda Martins ; Mônica Valeria Marquezini ; Nelson Ithiro Tanaka ; Paulo Afonso de André ; Paulo Justiniano Ribeiro Junior ; Paulo Sergio Panse Silveira ; Regina Maura de Miranda ; Reinaldo Paul Pérez Machado ; Renata Elaine Paraizo Leite ; Renata Eloah de Lucena Ferretti-Rebustini ; Ricardo Nitrini ; Ruy de Camargo Pires Neto ; Silvia Helena Gelás Lage ; Silvia Regina Dias Medici Saldiva ; Suzana Pasternak ; Tiana Carla Lopes Moreira ; William Nilson de Amorim ; Wilson Jacob Filho
• Associated grant(s): 19/07519-8 - 62nd ISI World Statistics Congress 2019, AR.EXT; 19/02898-0 - Airborne microplastics: detection in environmental air samples, lung tissue and effects on cultured lung epithelial cells, AP.R SPRINT; 16/50192-1 - Evaluation of new alternatives to increase the accuracy of the determination of cause of death: a public health approach, AP.R SPRINT; 15/50081-2 - Achieving sustainable food production and irrigation in São Paulo and Melbourne, AP.R SPRINT
• Associated scholarship(s): 19/03397-5 - Identification and physical-chemical characterization of environmental microplastics in the atmosphere and in human lung tissues, BP.PD; 18/24085-9 - Expression of RAGE in pulmonary tissue of patients diagnosed with sepsis and acute respiratory distress syndrome, BP.IC; 17/06670-9 - Co-benefits of the reduction of atmospheric pollution from the transport of passengers in São Paulo: an integrated economic evaluation of health impacts using different vehicle emission scenarios, BP.PD; + associated scholarships 17/10515-9 - Biomonitoring using tree bark and its correlation with particulate matter, BP.IC; 17/10514-2 - Green areas as filters of atmospheric pollution of vehicular emissions in the city of São Paulo, BP.IC; 17/10544-9 - Dendrochronology of Cedrela fissilis from an urban park in São Paulo, BP.IC; 17/09486-4 - Digital atlas of pathology, BP.IC; 16/23129-7 - Impact of long-term exposure to air pollution on myocardium ageing, BP.PD; 16/09411-1 - Spatio-temporal model for predicting the concentration of fine particulate matter (PM 2.5) in metropolitan area of São Paulo, BP.DR; 16/23339-1 - Molecular characterization and occurrence of organic compounds in gaseous and particulate phase in atmospheric particulate matter collected in Petrochemical Industry of Capuava (SP), BP.DD; 16/22793-0 - Alzheimer's Disease in the olfactory epithelium: correlation with the environment, BP.PD; 16/15989-6 - Green spaces and health: the impact of green spaces on the population of the Metropolitan Area of São Paulo, BP.PD; 16/17936-7 - Secondary aerosol: precursors and contribution to the atmospheric particulate matter, BP.PD; 16/03461-7 - Comparison of minimally invasive autopsy and conventional autopsy for post-mortem malignant neoplasm diagnosis, BP.PD; 15/25511-3 - Climate and pollution reconstruction based on urban tree-rings growth records, BP.PD; 15/03932-7 - MetroHealth Data Warehouse: Multidimensional Data Visualization and Data Extract, BP.TT; 15/02770-3 - The use of semi-automated and automated strategies for co registration and correlation between radiographic and pathologic image analysis in the central nervous system - a feasibility study, BE.PQ; 15/01798-1 - MetroHealth Data Warehouse: Conceptual Modeling and Implementation, BP.TT - associated scholarships

Abstract

Since ancient times, passing through the first known anatomic studies in the Middle Ages to the use of modern molecular techniques for the study of physiopathological processes, autopsy has shown to be a very rich source of material and inspiration for the advancement of scientific knowledge. Although a wide range of imaging techniques have emerged, several studies have shown that the autopsy remains crucial for: the complete assessment of the disease process, the assessment of new pathologies and quality control of the medical service. Autopsy also allows for the development of concomitant and associated projects in different areas due to the abundance of material. The School of Medicine of the University of Sao Paulo (FMUSP) seeks to make the best possible use of the great potential of its 14,000 annually autopsies Death Verification Service of Sao Paulo. Although it seems logical that the increased capacity of imaging techniques to observe biological alterations results in more reliable correlation, validations are, in general, conceptually performed on a daily basis of equipment use, based on assumptions, rather than in structured clinical/histological/imaging correlation studies. However, in spite of their several scientific contributions, the volume of studies post-mortem is small, as it is difficult to obtain specimens on a routine basis. The present proposal overarching goal is to use this new imaging facility to explore two important topics: (a) the concept of minimally invasive autopsy as an alternative to increase the number of autopsies, to understand diseases processes and to evaluate clinical diagnosis and treatment; and (b) the role of autopsy to investigate the effects of urban environment in determining human disease. (AU)

Scientific publications

(42)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LOCOSSELLI, GIULIANO MASELLI; LOPES MOREIRA, TIANA CARLA; CHACON-MADRIZ, KATHERINE; ZEZZI ARRUDA, MARCO AURELIO; DE CAMARGO, EVELYN PEREIRA; KAMIGAUTI, LEONARDO YOSHIAKI; FERREIRA DA TRINDADE, RICARDO IVAN; ANDRADE, MARIA DE FATIMA; SALDIVA DE ANDRE, CARMEN DIVA; DE ANDRE, PAULO AFONSO; et al. Spatial-temporal variability of metal pollution across an industrial district, evidencing the environmental inequality in Sao Paulo. Environmental Pollution, v. 263, n. A, AUG 2020. (15/25511-3, 17/10544-9, 13/21728-2)

LOCOSSELLI, GIULIANO MASELLI; BUCKERIDGE, MARCOS SILVEIRA. Dendrobiochemistry, a missing link to further understand carbon allocation during growth and decline of trees. TREES-STRUCTURE AND FUNCTION, v. 31, n. 6, p. 1745-1758, DEC 2017. (15/25511-3, 11/52065-3, 13/21728-2)

ZACCARELLI-MARINO, MARIA ANGELA; SALDIVA ANDRE, CARMEN DIVA; SINGER, JULIO M.. Overt Primary Hypothyroidism in an Industrial Area in Sao Paulo, Brazil: The Impact of Public Disclosure. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v. 13, n. 11, NOV 2016. (13/21728-2)

DE LIMA TAGA, MARCEL F.; SINGER, JULIO M.. Simple linear regression with interval censored dependent and independent variables. STATISTICAL METHODS IN MEDICAL RESEARCH, v. 27, n. 1, p. 198-207, JAN 2018. (13/21728-2)

ROCHA, FRANCISCO M. M.; SINGER, JULIO M.. Selection of terms in random coefficient regression models. Journal of Applied Statistics, v. 45, n. 2, p. 225-242, 2018. (13/21728-2)

MOREIRA, TIANA C. L.; AMATO-LOURENCO, LUIS F.; DA SILVA, GISELA T.; SALDIVA DE ANDRE, CARMEN D.; DE ANDRE, PAULO A.; BARROZO, LIGIA V.; SINGER, JULIO M.; SALDIVA, PAULO H. N.; SAIKI, MITIKO; LOCOSSELLI, GIULIANO M.. The Use of Tree Barks to Monitor Traffic Related Air Pollution: A Case Study in Sao Paulo-Brazil. FRONTIERS IN ENVIRONMENTAL SCIENCE, v. 6, JUL 13 2018. (13/21728-2, 14/19201-9, 15/25511-3)

SINGER, JULIO M.; ROCHA, FRANCISCO M. M.; PEDROSO-DE-LIMA, ANTONIO CARLOS; SILVA, GIOVANI L.; COATTI, GIULIANA C.; ZATZ, MAYANA. Random changepoint segmented regression with smooth transition. STATISTICAL METHODS IN MEDICAL RESEARCH, v. 30, n. 3, p. 643-654, MAR 2021. (13/21728-2)

DI DOMENICO, MARLISE; DE MENEZES BENEVENUTO, SARAH GOMES; TOMASINI, PAULA PELLENZ; YARIWAKE, VICTOR YUJI; ALVES, NILMARA DE OLIVEIRA; RAHMEIER, FRANCINE LUCIANO; FERNANDES, MARILDA DA CRUZ; MOURA, DINARA JAQUELINE; NASCIMENTO SALDIVA, PAULO HILARIO; VERAS, MARIANA MATERA. Concentrated ambient fine particulate matter (PM2.5) exposure induce brain damage in pre and postnatal exposed mice. NeuroToxicology, v. 79, p. 127-141, JUL 2020. (13/21728-2)

AMAIS, RENATA S.; MOREAU, PEDRO S.; FRANCISCHINI, DANIELLE S.; MAGNUSSON, RAFAEL; LOCOSSELLI, GIULIANO M.; GODOY-VEIGA, MILENA; CECCANTINI, GREGORIO; RODRIGUEZ, DAIGARD R. ORTEGA; TOMAZELLO-FILHO, MARIO; ARRUDA, MARCO A. Z.. Trace elements distribution in tropical tree rings through high-resolution imaging using LA-ICP-MS analysis. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, v. 68, DEC 2021. (19/24445-8, 20/09251-0, 13/21728-2, 17/50085-3, 18/22914-8, 18/25207-0, 15/25511-3, 18/23478-7, 19/08783-0, 19/00063-9, 17/50341-0, 19/00018-3, 19/05174-3)

COSTA, ELIARDO G.; PAULINO, CARLOS DANIEL; SINGER, JULIO M.. Verifying compliance with ballast water standards: a decision-theoretic approach. SORT-Statistics and Operations Research Transactions, v. 45, n. 1, p. 19-31, JAN-JUN 2021. (13/21728-2)

CAUMO, SOFIA; YERA, ALEINNYS B.; VICENTE, ANA; ALVES, CELIA; ROUBICEK, DEBORAH A.; VASCONCELLOS, PEROLA DE CASTRO. Particulate matter-bound organic compounds: levels, mutagenicity, and health risks. Environmental Science and Pollution Research, v. 29, n. 21, p. 18-pg., 2022-01-10. (16/23339-1, 13/21728-2, 17/20826-1)

DOS SANTOS, NATHALIA VILLA; ZILLI VIEIRA, CAROLINA LETICIA; NASCIMENTO SALDIVA, PAULO HILARIO; MAZZILLI, BARBARA PACI; SAIKI, MITIKO; SAUEIA, CATIA HELOISA; SALDIVA DE ANDRE, CARMEN DIVA; JUSTO, LISIE TOCCI; NISTI, MARCELO BESSA; KOUTRAKIS, PETROS. Levels of Polonium-210 in brain and pulmonary tissues: Preliminary study in autopsies conducted in the city of Sao Paulo, Brazil. SCIENTIFIC REPORTS, v. 10, n. 1, JAN 13 2020. (13/21728-2, 16/03461-7, 16/22793-0, 16/23129-7)

CAUMO, SOFIA; TRAUB, ALISON; EVANS, GREG; VASCONCELLOS, PEROLA DE CASTRO. Health risk assessment in atmosphere near a petrochemical industrial complex: Measuring oxidative potential and oxidative burden. ATMOSPHERIC POLLUTION RESEARCH, v. 13, n. 7, p. 10-pg., 2022-07-01. (13/21728-2, 16/23339-1)

MOREIRA, TIANA C. L.; POLIZEL, JEFFERSON L.; SANTOS, ITAMAR DE SOUZA; FILHO, DEMOSTENES F. SILVA; BENSENOR, ISABELA; LOTUFO, PAULO A.; MAUAD, THAIS. Green Spaces, Land Cover, Street Trees and Hypertension in the Megacity of Sao Paulo. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v. 17, n. 3, p. 14-pg., 2020-02-01. (16/15989-6, 13/21728-2)

FERREIRA, JOAO E.; TAKECIAN, PEDRO L.; KAMAURA, LEONARDO T.; PADILHA, BRUNO; PU, CALTON; IEEE. Dependency Management with WED-flow Techniques and Tools: A Case Study. 2017 IEEE 3RD INTERNATIONAL CONFERENCE ON COLLABORATION AND INTERNET COMPUTING (CIC), v. N/A, p. 10-pg., 2017-01-01. (13/21728-2, 15/01587-0, 15/03932-7, 15/01798-1)

SALDIVA DE ANDRE, CARMEN DIVA; BIERRENBACH, ANA LUIZA; BARROSO, LUCIA PEREIRA; DE ANDRE, PAULO AFONSO; JUSTO, LISIE TOCCI; AMADOR PEREIRA, LUIZ ALBERTO; TANIGUCHI, MAURO T.; MINTO, CATIA MARTINEZ; TAKECIAN, PEDRO LOSCO; KAMAURA, LEONARDO TADASHI; et al. Validation of physician certified verbal autopsy using conventional autopsy: a large study of adult non-external causes of death in a metropolitan area in Brazil. BMC PUBLIC HEALTH, v. 22, n. 1, p. 11-pg., 2022-04-14. (13/21728-2)

MOREIRA, TIANA C. L.; POLIZE, JEFFERSON L.; BRITO, MARCELI; DA SILVA FILHO, DEMOSTENES F.; CHIAVEGATO FILHO, ALEXANDRE D. P.; VIANA, MARIA CARMEM; ANDRADE, LAURA HELENA; MAUAD, THAIS. Assessing the impact of urban environment and green infrastructure on mental health: results from the Sao Paulo Megacity Mental Health Survey. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, v. 32, n. 2, p. 8-pg., 2021-06-11. (13/21728-2, 16/50307-3, 03/00204-3, 16/15989-6)

CORDER, RODRIGO M.; DE LIMA, ANTONIO C. P.; KHOURY, DAVID S.; DOCKEN, STEFFEN S.; DAVENPORT, MILES P.; FERREIRA, MARCELO U.. Quantifying and preventingPlasmodium vivaxrecurrences in primaquine-untreated pregnant women: An observational and modeling study in Brazil. PLoS Neglected Tropical Diseases, v. 14, n. 7, JUL 2020. (13/21728-2, 16/18740-9, 17/50292-9)

LOCOSSELLI, GIULIANO MASELLI; CHACON-MADRID, KATHERINE; ZEZZI ARRUDA, MARCO AURELIO; DE CAMARGO, EVELYN PEREIRA; LOPES MOREIRA, TIANA CARLA; SALDIVA DE ANDRE, CARMEN DIVA; DE ANDRE, PAULO AFONSO; SINGER, JULIO M.; NASCIMENTO SALDIVA, PAULO HILARIO; BUCKERIDGE, MARCOS SILVEIRA. Tree rings reveal the reduction of Cd, Cu, Ni and Pb pollution in the central region of Sao Paulo, Brazil. Environmental Pollution, v. 242, n. A, p. 320-328, NOV 2018. (15/25511-3, 16/07384-7, 17/10544-9, 13/21728-2)

MOREIRA, TIANA C. L.; POLIZEL, JEFFERSON L.; SANTOS, ITAMAR DE SOUZA; FILHO, DEMOSTENES F. SILVA; BENSENOR, ISABELA; LOTUFO, PAULO A.; MAUAD, THAIS. Green Spaces, Land Cover, Street Trees and Hypertension in the Megacity of Sao Paulo. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v. 17, n. 3, FEB 1 2020. (13/21728-2, 16/15989-6)

MOREIRA, TIANA C. L.; POLIZE, JEFFERSON L.; BRITO, MARCELI; DA SILVA FILHO, DEMOSTENES F.; CHIAVEGATO FILHO, ALEXANDRE D. P.; VIANA, MARIA CARMEM; ANDRADE, LAURA HELENA; MAUAD, THAIS. Assessing the impact of urban environment and green infrastructure on mental health: results from the Sao Paulo Megacity Mental Health Survey. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, JUN 2021. (03/00204-3, 16/15989-6, 16/50307-3, 13/21728-2)

LOCOSSELLI, GIULIANO MASELLI; DE CAMARGO, EVELYN PEREIRA; LOPES MOREIRA, TIANA CARLA; TODESCO, ENZO; ANDRADE, MARIA DE FATIMA; SALDIVA DE ANDRE, CARMEN DIVA; DE ANDRE, PAULO AFONSO; SINGER, JULIO M.; FERREIRA, LUCIANA SCHWANDNER; NASCIMENTO SALDIVA, PAULO HILARIO; et al. The role of air pollution and climate on the growth of urban trees. Science of The Total Environment, v. 666, p. 652-661, MAY 20 2019. (15/25511-3, 17/10544-9, 08/57908-6, 13/21728-2)

CREMASCO TAKANO, ANA PAULA; JUSTO, LISIE TOCCI; DOS SANTOS, NATHALIA VILLA; MARQUEZINI, MONICA VALERIA; DE ANDRE, PAULO AFONSO; MONTEIRO DA ROCHA, FRANCISCO MARCELO; PASQUALUCCI, CARLOS AUGUSTO; BARROZO, LIGIA VIZEU; SINGER, JULIO M.; SALDIVA DE ANDRE, CARMEN DIVA; et al. Pleural anthracosis as an indicator of lifetime exposure to urban air pollution: An autopsy-based study in Sao Paulo. Environmental Research, v. 173, p. 23-32, JUN 2019. (16/22793-0, 16/23129-7, 16/03461-7, 13/21728-2)

ZERBINI, TALITA; PERCINIO GIANVECCHIO, VICTOR ALEXANDRE; REGINA, DAMARIS; TSUJIMOTO, TAMY; RITTER, VICTOR; SINGER, JULIO M.. Suicides by hanging and its association with meteorological conditions in Sao Paulo. JOURNAL OF FORENSIC AND LEGAL MEDICINE, v. 53, p. 22-24, JAN 2018. (13/21728-2)

LOCOSSELLI, GIULIANO MASELLI; BRIENEN, ROEL J. W.; DE SOUZA MARTINS, VERIDIANA TEIXEIRA; GLOOR, EMANUEL; BOOM, ARNOUD; DE CAMARGO, EVELYN PEREIRA; NASCIMENTO SALDIVA, PAULO HILARIO; BUCKERIDGE, MARCOS SILVEIRA. Intra-annual oxygen isotopes in the tree rings record precipitation extremes and water reservoir levels in the Metropolitan Area of Sao Paulo, Brazil. Science of The Total Environment, v. 743, p. 8-pg., 2020-11-15. (13/21728-2, 18/22422-8, 17/50085-3, 19/08783-0, 15/25511-3, 10/20876-0, 17/10544-9)

BARROZO, LIGIA VIZEU; FORNACIALI, MICHEL; SALDIVA DE ANDRE, CARMEN DIVA; ZIMEO MORAIS, GUILHERME AUGUSTO; MANSUR, GISELLE; CABRAL-MIRANDA, WILLIAM; DE MIRANDA, MARINA JORGE; SATO, JOAO RICARDO; AMARO JUNIOR, EDSON. GeoSES: A socioeconomic index for health and social research in Brazil. PLoS One, v. 15, n. 4, APR 29 2020. (13/21728-2)

COSTA, ELIARDO G.; PAULINO, CARLOS DANIEL; SINGER, JULIO M.. Optimal sample size for estimating the mean concentration of invasive organisms in ballast water via a semiparametric Bayesian analysis. Statistical Methods and Applications, v. N/A, p. 18-pg., 2022-05-13. (13/21728-2)

PEREIRA, GUILHERME MARTINS; DA SILVA CAUMO, SOFIA ELLEN; MOTA NASCIMENTO, EMERSON QUEIROZ; PARRA, YENDRY JOMOLCA; VASCONCELLOS, PEROLA DE CASTRO. Polycyclic aromatic hydrocarbons in tree barks, gaseous and particulate phase samples collected near an industrial complex in Sao Paulo (Brazil). Chemosphere, v. 237, DEC 2019. (13/21728-2)

LOCOSSELLI, GIULIANO MASELLI; BRIENEN, ROEL J. W.; LEITE, MELINA DE SOUZA; GLOOR, MANUEL; KROTTENTHALER, STEFAN; DE OLIVEIRA, ALEXANDRE A.; BARICHIVICH, JONATHAN; ANHUF, DIETER; CECCANTINI, GREGORIO; SCHONGART, JOCHEN; et al. Global tree-ring analysis reveals rapid decrease in tropical tree longevity with temperature. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v. 117, n. 52, p. 33358-33364, DEC 29 2020. (17/50085-3, 15/25511-3, 20/09251-0, 19/08783-0, 13/21728-2, 08/57908-6)

BAILEY, ADAM L.; KANG, I, LIANG-; FRANCISCO DE ASSIS BARROS D'ELIA ZANELLA, LUIZ GONZAGA; SILVEIRA, CASSIA G. T.; HO, YEH-LI; FOQUET, LANDER; BIAL, GREG; MCCUNE, BROC T.; DUARTE-NETO, AMARO NUNES; THOMAS, ARCHANA; et al. Consumptive coagulopathy of severe yellow fever occurs independently of hepatocellular tropism and massive hepatic injury. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v. 117, n. 51, p. 32648-32656, DEC 22 2020. (16/01735-2, 13/21728-2)

CUNHA, MARIELTON DOS PASSOS; DUARTE-NETO, AMARO NUNES; POUR, SHAHAB ZAKI; ORTIZ-BAEZ, AYDA SUSANA; CERNY, JIRI; DE SOUZA PEREIRA, BARBARA BRITO; BRACONI, CARLA TORRES; HO, YEH-LI; PERONDI, BEATRIZ; SZTAJNBOK, JAQUES; et al. Origin of the Sao Paulo Yellow Fever epidemic of 2017-2018 revealed through molecular epidemiological analysis of fatal cases. SCIENTIFIC REPORTS, v. 9, DEC 31 2019. (17/23281-6, 13/25434-3, 13/21728-2, 16/08204-2)

GODOY-VEIGA, MILENA; SLOTTA, FRANZISKA; ALECIO, PAULA CHRISTIANI; CECCANTINI, GREGORIO; BUCKERIDGE, MARCOS SILVEIRA; LOCOSSELLI, GIULIANO MASELLI. Improved tree-ring visualization using autofluorescence. DENDROCHRONOLOGIA, v. 55, p. 33-42, JUN 2019. (13/21728-2, 15/25511-3, 17/50085-3, 08/57908-6)

DOMBROWSKI, JAMILLE GREGORIO; DE SOUZA, RODRIGO MEDEIROS; LIMA, FLAVIA AFONSO; BANDEIRA, CARLA LETICIA; MURILLO, OSCAR; COSTA, DOUGLAS DE SOUSA; MACHADO PEIXOTO, ERIKA PAULA; CUNHA, MARIELTON DOS PASSOS; DE ANDRADE ZANOTTO, PAOLO MARINHO; BEVILACQUA, ESTELA; et al. Association of Malaria Infection During Pregnancy With Head Circumference of Newborns in the Brazilian Amazon. JAMA NETWORK OPEN, v. 2, n. 5, MAY 2019. (14/17766-9, 18/20468-0, 12/04755-3, 13/21728-2, 14/20451-0, 14/09964-5, 15/06106-0, 13/00981-1, 16/08204-2, 13/16417-8, 09/53889-0)

SINGER, JULIO M.; ROCHA, FRANCISCO M. M.; ANDRE, CARMEN D. S.; ZERBINI, TALITA. Fitting mixed models to messy longitudinal data: A case study involving estimation of post mortem intervals. BRAZILIAN JOURNAL OF PROBABILITY AND STATISTICS, v. 33, n. 1, p. 161-183, FEB 2019. (13/21728-2)

PASQUA, LEONARDO ALVES; DAMASCENO, MAYARA VIEIRA; CRUZ, RAMON; MATSUDA, MONIQUE; MARTINS, MARCO GARCIA; LIMA-SILVA, ADRIANO EDUARDO; MARQUEZINI, MONICA; NASCIMENTO SALDIVA, PAULO HILARIO; BERTUZZI, ROMULO. Exercising in Air Pollution: The Cleanest versus Dirtiest Cities Challenge. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v. 15, n. 7, JUL 2018. (13/21728-2)

DOS SANTOS, NATHALIA VILLA; VIEIRA, CAROLINA LETICIA ZILLI; SALDIVA, PAULO HILARIO NASCIMENTO; DE ANDRE, CARMEN DIVA SALDIVA; MAZZILLI, BARBARA PACI; ANDRADE, MARIA DE FATIMA; SAUEIA, CATIA HELOISA; SAIKI, MITIKO; VERAS, MARIANA MATERA; KOUTRAKIS, PETROS. Accumulation of trace element content in the lungs of Sao Paulo city residents and its correlation to lifetime exposure to air pollution. SCIENTIFIC REPORTS, v. 12, n. 1, p. 7-pg., 2022-06-30. (16/22793-0, 13/21728-2, 16/03461-7, 16/23129-7)

CORDER, RODRIGO M.; DE LIMA, ANTONIO C. P.; KHOURY, DAVID S.; DOCKEN, STEFFEN S.; DAVENPORT, MILES P.; FERREIRA, MARCELO U.. Quantifying and preventing Plasmodium vivax recurrences in primaquine-untreated pregnant women: An observational and modeling study in Brazil. PLoS Neglected Tropical Diseases, v. 14, n. 7, p. 16-pg., 2020-07-01. (17/50292-9, 13/21728-2, 16/18740-9)

LOCOSSELLI, GIULIANO MASELLI; LOPES MOREIRA, TIANA CARLA; CHACON-MADRIZ, KATHERINE; ZEZZI ARRUDA, MARCO AURELIO; DE CAMARGO, EVELYN PEREIRA; KAMIGAUTI, LEONARDO YOSHIAKI; FERREIRA DA TRINDADE, RICARDO IVAN; ANDRADE, MARIA DE FATIMA; SALDIVA DE ANDRE, CARMEN DIVA; DE ANDRE, PAULO AFONSO; et al. Spatial-temporal variability of metal pollution across an industrial district, evidencing the environmental inequality in Sao Paulo. Environmental Pollution, v. 263, p. 8-pg., 2020-08-01. (13/21728-2, 15/25511-3, 17/10544-9)

ALVES, NILMARA DE OLIVEIRA; PEREIRA, GUILHERME MARTINS; DI DOMENICO, MARLISE; COSTANZO, GIOVANNA; BENEVENUTO, SARAH; FONOFF, ADRIANA M. DE OLIVEIRA; XAVIER COSTA, NATALIA DE SOUZA; RIBEIRO, JR., GABRIEL; KAJITANI, GUSTAVO SATORU; MORENO, NATALIA CESTARI; et al. Inflammation response, oxidative stress and DNA damage caused by urban air pollution exposure increase in the lack of DNA repair XPC protein. Environment International, v. 145, DEC 2020. (17/17047-0, 19/19435-3, 13/21728-2)

CUNHA, MARIELTON DOS PASSOS; DUARTE-NETO, AMARO NUNES; POUR, SHAHAB ZAKI; HAJJAR, LUDHMILA ABRAHAO; FRASSETTO, FERNANDO PEREIRA; DOLHNIKOFF, MARISA; DO NASCIMENTO SALDIVA, PAULO HILARIO; DE ANDRADE ZANOTTO, PAOLO MARINHO. Systemic dengue infection associated with a new dengue virus type 2 introduction in Brazil - a case report. BMC INFECTIOUS DISEASES, v. 21, n. 1, APR 1 2021. (20/04602-9, 13/21728-2, 17/23281-6, 16/08204-2)

HART, JOHN D.; DE ANDRE, PAULO AFONSO; SALDIVA DE ANDRE, CARMEN DIVA; ADAIR, TIM; BARROSO, LUCIA PEREIRA; VALONGUEIRO, SANDRA; BIERRENBACH, ANA LUIZA; DE CARVALHO, PATRICIA ISMAEL; DE CERQUEIRA ANTUNES, MARIA BERNADETE; DE OLIVEIRA, CONCEICAO MARIA; et al. Validation of SmartVA using conventional autopsy: A study of adult deaths in Brazil. LANCET REGIONAL HEALTH-AMERICAS, v. 5, p. 8-pg., 2022-01-01. (13/21728-2)

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