INCT 2014: biodiversidade e produtos naturais

• Processo: 14/50926-0
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Temático
• Data de Início da vigência: 01 de julho de 2017
• Data de Término da vigência: 30 de abril de 2025
• Área do conhecimento: Ciências Exatas e da Terra - Química
• Acordo de Cooperação: CNPq - INCTs
• Pesquisador responsável: Vanderlan da Silva Bolzani
• Beneficiário: Vanderlan da Silva Bolzani
• Instituição Sede: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brasil
• Município da Instituição Sede: Araraquara
• Pesquisadores principais:( Últimos ): Ian Castro-Gamboa ; Leticia Veras Costa Lotufo
• Pesquisadores principais:( Antigos ): Alberto Jose Cavalheiro ; Maria José Soares Mendes Giannini
• Auxílio(s) vinculado(s): 23/09497-7 - American Society of Pharmacognosy 2023 Annual Meeting, AR.EXT; 18/50025-3 - Green analytical chemistry applied to the investigation of agro industrial wastes generated in Brazil and Australia, AP.R SPRINT
• Bolsa(s) vinculada(s): 24/14964-6 - Mecanismos de controle da Apoptose na Carcinogênese e na Quimiorresistência: papel das proteínas inibidoras de apoptose como alvo terapêutico no melanoma, BP.DR; 24/02602-2 - Metabolômica, uma metodologia de vanguarda para a identificação micromolecular e estudos de quimiossistemática em Bignoniaceae, BP.DR; 24/05515-3 - Perspectivas químicas e biológicas para o isolamento, caracterização e síntese de ciclopeptídeos de plantas, BP.PD; 23/00454-3 - Avaliação de novos inibidores duais de histona desacetilases e metaloproteinases em linhagens celulares de glioblastoma, BP.IC; 23/02775-1 - Prospecção de novas substâncias com potencial anticâncer em bactérias isoladas da ascídia Trididemnum maragogi, BP.IC
• Assunto(s): Biodiversidade Produtos naturais Metabólitos secundários Pesquisa básica Desenvolvimento de produtos Sustentabilidade Micro-organismos
• Palavra(s)-Chave do Pesquisador: Quimica
• Publicação FAPESP: https://media.fapesp.br/bv/uploads/pdfs/Brazilian_biodiversity...future_syWaC2Z_55_56.pdf

Resumo

O projeto delineado está centrado nos pilares de sustentação da Ciência, Tecnologia e Inovação, que norteiam as sociedades do conhecimento: (a) pesquisa básica e aplicada de excelência; (b) formação de recursos humanos em biodiversidade e produtos naturais; (c) colaboração com o setor empresarial para desenvolvimento tecnológico a partir das inovações em produtos naturais; (d) difusão do conhecimento sobre a biodiversidade e produtos naturais bioativos para o ensino médio e outros segmentos da sociedade; (e) contribuição nas ações de políticas públicas de conservação e uso sustentável da biodiversidade. Dentro destes fundamentos, o Instituto Nacional de Ciência & Tecnologia (INCTBioNat) foi criado para mapear e catalogar de forma organizada todas as informações sobre os metabólitos secundários detectados e/ou isolados de organismos de nossa rica biodiversidade, fundamental para o avanço de pesquisa em química de produtos naturais do Brasil. O conhecimento e uso sustentável da biodiversidade brasileira foi preconizado no documento Política Nacional da Biodiversidade, editado pela Secretaria de Biodiversidade e Florestas (SBF), Ministério do Meio Ambiente (MMA), em 2002 e tem prioridade para o desenvolvimento nacional. A criação de uma rede nacional de pesquisa para mapeamento químico e biológico das espécies terrestres, marinhas e de microrganismos da nossa biodiversidade constitui-se numa estratégia racional para a seleção de substâncias ativas mais promissoras para posterior estudos farmacológicos e toxicológicos visando moléculas protótipos. Para atingir tais metas, o ICNTBioNat reúne pesquisadores de excelência e pesquisadores jovens e talentosos que iniciam suas carreiras em universidades federais e estaduais de vários estados da federação, englobando todas as regiões do Brasil. Toda equipe atuará de forma colaborativa e multidisciplinar objetivando o fortalecimento de uma área de pesquisa e inovação estratégica para o Brasil, através de uma rede de laboratórios de excelência em produtos naturais para exploração e uso sustentável da rica biodiversidade brasileira. (AU)

Publicações científicas

(165)

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

MAIARA S. BORGES; CAROLINA R. BIASETTO; VANESSA M. CHAPLA; SAMAD N. EBRAHIMI; MAYRA F. COSTA; VANDERLAN S. BOLZANI; ANGELA R. ARAUJO. Assessment of Novel C-4 Methylated Tetraketide by HPLC-SPE-TT in Saccharicola sp., an Endophytic Fungus in Eugenia jambolana Lam.. Journal of the Brazilian Chemical Society, v. 30, n. 3, p. 522-527, 2019-03-00. (14/50926-0, 13/07600-3)

DANIELE RODRIGUES DE LIMA; MARIA GLEIZIANE DE ARAÚJO FRANCA; FÁTIMA DE CÁSSIA EVANGELISTA DE OLIVEIRA; CLÁUDIA DO Ó PESSOA; ALBERTO JOSÉ CAVALHEIRO; MARIA GORETTI DE VASCONCELOS SILVA. METABOLIC PROFILING AND CYTOTOXIC ACTIVITY OF METHANOL EXTRACTS FROM CHAMAECRISTA DUCKEANA (P. BEZERRA & A. FERN.) H. S. IRWIN & BARNEBY (LEGUMINOSAE, CAESALPINIOIDEAE). Química Nova, v. 45, n. 7, p. 803-806, 2022-09-26. (13/07600-3, 14/50926-0)

BERTOZO, LUIZA DE CARVALHO; NETO, ERNESTO TAVARES; DE OLIVEIRA, LEANDRO CRISTANTE; XIMENES, VALDECIR FARIAS. Oxidative Alteration of Trp-214 and Lys-199 in Human Serum Albumin Increases Binding Affinity with Phenylbutazone: A Combined Experimental and Computational Investigation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 19, n. 10, OCT 2018. (14/50926-0, 16/20549-5, 16/22014-1)

FERREIRA SANTOS, NATACHA CARVALHO; VALLI, MARILIA; BOLZANI, VANDERLAN DA SILVA. A brief overview on Brazilian women in chemistry. Pure and Applied Chemistry, v. 91, n. 4, SI, p. 743-749, APR 2019. (14/50926-0, 13/07600-3)

NUNES, WILHAN DONIZETE GONCALVES; RUSSO, HELENA MANNOCHIO; BOLZANI, VANDERLAN DA SILVA; CAIRES, FLAVIO JUNIOR. Thermal characterization and compounds identification of commercialStevia rebaudianaBertoni sweeteners and thermal degradation products at high temperatures by TG-DSC, IR and LC-MS/MS. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, AUG 2020. (18/24378-6, 14/50926-0, 13/07600-3, 16/16970-7)

DE FREITAS, LARISSA; VALLI, MARILIA; DAMETTO, ALESSANDRA C.; PENNACCHI, PAULA C.; ANDRICOPULO, ADRIANO D.; MARIA-ENGLER, SILVYA S.; BOLZANI, VANDERLAN S.. Advanced Glycation End Product Inhibition by Alkaloids from Ocotea paranapiacabensis for the Prevention of Skin Aging. Journal of Natural Products, v. 83, n. 3, SI, p. 649-656, MAR 27 2020. (14/50926-0, 19/05967-3, 13/07600-3)

DANUELLO, AMANDA; DE CASTRO, ROGERIO CARDOSO; PILON, ALAN CESAR; PIRES BUENO, PAULA CAROLINA; PIVATTO, MARCOS; VIEIRA JUNIOR, GERARDO MAGELA; CARVALHO, FLAVIO ALEXANDRE; ODA, FERNANDO BOMBARDA; PEREZ, CONSUELO JAVIERA; LOPES, NORBERTO PEPORINE; et al. Fragmentation study of clerodane diterpenes from Casearia species by tandem mass spectrometry (quadrupole time-of-flight and ion trap). RAPID COMMUNICATIONS IN MASS SPECTROMETRY, v. 34, n. 3, SI, MAY 2020. (11/21440-3, 16/13292-8, 17/19702-6, 13/07600-3, 14/50926-0)

FUNARI, CRISTIANO SOLEO; CAVALHEIRO, ALBERTO JOSE; CARNEIRO, RENATO LAJARIM. Coupled monolithic columns as an alternative for the use of viscous ethanol-water mobile phases on chromatographic fingerprinting complex samples. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 28, n. 3, p. 261-266, MAY-JUN 2018. (14/50926-0, 13/07600-3, 10/18840-7)

WOLF, VANESSA GONCALVES; BONACORSI, CIBELE; GONCALVES RADDI, MARIA STELLA; DA FONSECA, LUIZ MARCOS; XIMENES, VALDECIR FARIAS. Octyl gallate, a food additive with potential beneficial properties to treat Helicobacter pylori infection. FOOD & FUNCTION, v. 8, n. 7, p. 2500-2511, JUL 1 2017. (14/50926-0, 15/21693-0)

VALLI, MARILIA; BOLZANI, VANDERLAN S.. Natural Products: Perspectives and Challenges for use of Brazilian Plant Species in the Bioeconomy. Anais da Academia Brasileira de Ciências, v. 91, n. 3, 2019. (03/02176-7, 14/50926-0, 13/07600-3)

AGUINALDO ROBINSON DE SOUZA; IZABELLE AMORIM FERREIRA BOZA; VALDECIR FARIAS XIMENES; MAURÍCIO IKEDA YOGUIN; MARÍA-JOSÉ DÁVILA-RODRIGUEZ; NELSON HENRIQUE MORGON; IGNEZ CARACELLI. ELUCIDAÇÃO DA QUIRALIDADE INDUZIDA NA MOLÉCULA DANSILGLICINA NA COMPLEXAÇÃO COM A PROTEÍNA ALBUMINA DO SORO HUMANO (HSA). Química Nova, v. 42, n. 2, p. 135-142, 2019-02-00. (16/20549-5, 14/50926-0, 15/22338-9)

SALDIVAR-GONZALEZ, FERNANDA I.; VALLI, MARILIA; ANDRICOPULO, ADRIANO D.; BOLZANI, VANDERLAN DA SILVA; MEDINA-FRANCO, JOSE L.. Chemical Space and Diversity of the NuBBE Database: A Chemoinformatic Characterization. JOURNAL OF CHEMICAL INFORMATION AND MODELING, v. 59, n. 1, p. 74-85, JAN 2019. (14/50926-0, 13/07600-3)

XIMENES, VALDECIR FARIAS; MORGON, NELSON HENRIQUE; DE SOUZA, AGUINALDO ROBINSON. Solvent-dependent inversion of circular dichroism signal in naproxen: An unusual effect!. CHIRALITY, v. 30, n. 9, p. 1049-1053, SEP 2018. (14/50926-0, 15/22338-9, 16/20549-5)

GOMEZ-GARCIA, ALEJANDRO; JIMENEZ, DANIEL A. ACUNA; ZAMORA, WILLIAM J.; BARAZORDA-CCAHUANA, HARUNA L.; CHAVEZ-FUMAGALLI, MIGUEL A.; VALLI, MARILIA; ANDRICOPULO, ADRIANO D.; BOLZANI, VANDERLAN DA S.; OLMEDO, DIONISIO A.; SOLIS, PABLO N.; et al. Latin American Natural Product Database (LANaPDB): An Update. JOURNAL OF CHEMICAL INFORMATION AND MODELING, v. 64, n. 22, p. 15-pg., 2024-11-06. (20/11967-3, 14/50926-0, 22/08333-8, 13/07600-3)

DE LIMA, LAIS RAMOS MONTEIRO; SILVA, MARIA FRANCILENE SOUZA; ARAUJO, GISELE S.; RIBEIRO, FABIO DE OLIVEIRA SILVA; RIBEIRO, IRISVAN S.; PESSOA, CLAUDIA; COSTA FILHO, RAIMUNDO N.; MARINHO FILHO, JOSE DELANO B.; ARAUJO, ANA JERSIA; DA SILVA, DURCILENE ALVES; et al. Doxorubicin-galactomannan nanoconjugates for potential cancer treatment. Carbohydrate Polymers, v. 342, p. 11-pg., 2024-06-10. (14/50926-0)

ESPINOZA-CHAVEZ, ROCIO MARISOL; REZENDE JUNIOR, CELSO DE OLIVEIRA; DE SOUZA, MARIANA LAUREANO; CHELUCCI, RAFAEL CONSOLIN; MICHELAN-DUARTE, SIMONE; KROGH, RENATA; FERREIRA, LEONARDO LUIZ GOMES; VALLI, MARILIA; DE OLIVEIRA, ALDO SENA; ANDRICOPULO, ADRIANO D.; et al. Structure-Metabolism Relationships of Benzimidazole Derivatives with anti-Trypanosoma cruzi Activity for Chagas Disease. CHEMMEDCHEM, v. 19, n. 20, p. 21-pg., 2024-08-27. (18/14268-9, 13/25658-9, 20/11967-3, 14/50926-0, 19/05967-3, 15/50655-9, 22/08333-8, 13/07600-3, 15/09080-2)

CHIBLI, LUCAS APOLINARIO; DE LIMA, BRUNA RIBEIRO; CARNEIRO, ARIADNE MAGALHAES; FIGUEIRO, HARLEY CARDOSO; CICEK, SERHAT SEZAI; SPIEGLER, VERENA; FUNARI, CRISTIANO SOLEO. Toward a More Sustainable Sample Preparation in Phytochemistry: Case Studies in Four Subclasses of Alkaloids. Journal of Natural Products, v. 87, n. 3, p. 10-pg., 2024-02-21. (18/01786-1, 14/50926-0, 17/06216-6)

JORDAO, ANA CAROLINA; DOS SANTOS, GUSTAVO SOUZA; TEIXEIRA, THAIZ RODRIGUES; GLUZEZAK, ANA JULIA PASUCH; AZEVEDO, CLARISSA BECHUATE DE SOUZA; PEREIRA, KARINA DE CASTRO; TONANI, LUDMILLA; GASPAR, LORENA RIGO; KRESS, MARCIA REGINA VON ZESKA; COLEPICOLO, PIO; et al. Assessment of the photoprotective potential and structural characterization of secondary metabolites of Antarctic fungus Arthrinium sp.. Archives of Microbiology, v. 206, n. 1, p. 16-pg., 2024-01-01. (17/03552-5, 14/50926-0)

BORGES, MAIARA S.; BIASETTO, CAROLINA R.; CHAPLA, VANESSA M.; EBRAHIMI, SAMAD N.; COSTA, MAYRA F.; BOLZANI, VANDERLAN S.; ARAUJO, ANGELA R.. Assessment of Novel C-4 Methylated Tetraketide by HPLC-SPE-TT in Saccharicola sp., an Endophytic Fungus in Eugenia jambolana Lam. Journal of the Brazilian Chemical Society, v. 30, n. 3, p. 6-pg., 2019-03-01. (13/07600-3, 14/50926-0)

BIM-JUNIOR, ODAIR; GAGLIERI, CAROLINE; BEDRAN-RUSSO, ANA K.; BUENO-SILVA, BRUNO; BANNACH, GILBERT; FREM, REGINA; XIMENES, VALDECIR FARIAS; LISBOA-FILHO, PAULO N.. MOF-Based Erodible System for On-Demand Release of Bioactive Flavonoid at the Polymer-Tissue Interface. ACS BIOMATERIALS SCIENCE & ENGINEERING, v. 6, n. 8, p. 4539-4550, AUG 2020. (17/08820-8, 14/50926-0, 18/02186-8)

ASSE JUNIOR, LEONARDO RANDER; KRONENBERGER, THALES; MAGALHAES SERAFIM, MATEUS SA; SOUSA, YAMARA VIANA; FRANCO, ISABELLA DRUMOND; VALLI, MARILIA; BOLZANI, VANDERLAN DA SILVA; MONTEIRO, GUSTAVO CLARO; BRUNO PRATES, JOAO LUCAS; KROON, ERNA GEESSIEN; et al. Virtual screening of antibacterial compounds by similarity search of Enoyl-ACP reductase (FabI) inhibitors. Future Medicinal Chemistry, v. 12, n. 1, p. 51-68, JAN 2020. (19/05967-3, 14/50926-0, 13/07600-3)

RIBEIRO, SABRINA M.; FRATUCELLI, ERICK D. O.; BUENO, PAULA C. P.; DE CASTRO, V, MARLENE KELLY; FRANCISCO, AMANDA ALCALA; CAVALHEIRO, ALBERTO JOSE; KLEIN, I, MARLISE. Antimicrobial and antibiofilm activities of Casearia sylvestris extracts from distinct Brazilian biomes against Streptococcus mutans and Candida albicans. BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, v. 19, n. 1, NOV 12 2019. (13/07600-3, 14/50926-0, 11/21440-3, 12/21921-4, 17/07408-6)

CARNEIRO, ARIADNE MAGALHAES; MOREIRA, EDUARDA ANTUNES; BRAGAGNOLO, FELIPE SANCHEZ; BORGES, MAIARA STEFANINI; PILON, ALAN CESAR; RINALDO, DANIEL; FUNARI, CRISTIANO SOLEO. Soya agricultural waste as a rich source of isoflavones. Food Research International, v. 130, APR 2020. (16/13292-8, 14/50926-0, 16/08179-8, 17/06216-6)

FERRARI, ANNA BEATRIZ SABINO; MARCHEAFAVE, GUSTAVO GALO; MANNOCHIO-RUSSO, HELENA; BOLZANI, VANDERLAN DA SILVA; ZIED, DIEGO CUNHA; SCARMINIO, IEDA SPACINO; ZERAIK, MARIA LUIZA. Chemical composition and chromatographic fingerprint of three strains of Agaricus subrufescens cultivated with handmade and commercial supplements. Food Chemistry, v. 363, NOV 30 2021. (14/50926-0, 13/07600-3)

DA SILVA, GISELLE LOPES; CAMPIDELI, MARIANA BORDIN; SABINO FERRARI, ANNA BEATRIZ; MANNOCHIO-RUSSO, HELENA; FRAIGE, KARINA; DAMETTO, ALESSANDRA CRISTINA; BOLZANI, VANDERLAN DA SILVA; ZERAIK, MARIA LUIZA. In vitro antiglycation and antioxidant properties of Eugenia pyriformis leaves and fruits. NATURAL PRODUCT RESEARCH, NOV 2021. (13/07600-3, 14/50926-0)

DA SILVA, JAFF RIBEIRO; DE CERQUEIRA E SILVA, MARIANA BARROS; PHILADELPHO, BIANE OLIVEIRA; DE SOUZA, VICTORIA CRUZ; MACHADO DOS SANTOS, JOHNNIE ELTON; CASTILHO, MARCELO SANTOS; FERREIRA, EDERLAN DE SOUZA; CILLI, EDUARDO MAFFUD. PyrGF and GSTLN peptides enhance pravastatin's inhibition of 3-hydroxy-3-methyl-glutaryl coenzyme. FOOD BIOSCIENCE, v. 44, n. B, DEC 2021. (13/07600-3, 14/50926-0)

MAZZEU, BRUNA F.; SOUZA-MOREIRA, TATIANA M.; OLIVEIRA, ANDREW A.; REMLINGER, MELISSA; FELIPPE, LIDIANE G.; VALENTINI, SANDRO R.; GUIDO, RAFAEL V. C.; ZANELLI, CLESLEI F.; FURLAN, MAYSA. The Methionine 549 and Leucine 552 Residues of Friedelin Synthase from Maytenus ilicifolia Are Important for Substrate Binding Specificity. Molecules, v. 26, n. 22, NOV 2021. (13/07600-3, 11/10379-1, 14/25705-0, 14/50926-0)

ZERAIK, MARIA LUIZA; PAULI, IVANI; DUTRA, LUIZ A.; CRUZ, RAQUEL S.; VALLI, MARILIA; PARACATU, LUANA C.; DE FARIA, CAROLINA M. Q. G.; XIMENES, VALDECIR F.; REGASINI, LUIS O.; ANDRICOPULO, ADRIANO D.; et al. Identification of a Prenyl Chalcone as a Competitive Lipoxygenase Inhibitor: Screening, Biochemical Evaluation and Molecular Modeling Studies. Molecules, v. 26, n. 8, APR 2021. (10/01506-7, 13/07600-3, 11/03017-6, 19/05967-3, 19/18445-5, 09/15457-0, 14/50926-0)

BIASETTO, CAROLINA R.; SOMENSI, ANDRESSA; SORDI, RENATA; CHAPLA, VANESSA M.; EBRAHIMI, SAMAD N.; SILVA, GERALDO H.; TELES, HELDER L.; BOLZANI, VANDERLAN DA S.; YOUNG, MARIA CLAUDIA M.; PFENNING, LUDWIG H.; et al. The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl. PHYTOCHEMISTRY LETTERS, v. 36, p. 106-110, APR 2020. (14/50926-0, 13/07600-3, 03/02176-7)

BICALHO, KEYLLA U.; SANTONI, MARIANA M.; ARENDT, PHILIPP; ZANELLI, CLESLEI F.; FURLAN, MAYSA; GOOSSENS, ALAIN; POLLIER, JACOB. CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway. Plant and Cell Physiology, v. 60, n. 11, p. 2510-2522, NOV 2019. (14/50926-0, 13/07600-3, 15/25175-3, 17/10911-1, 16/16970-7)

DE ALMEIDA, LARISSA COSTA; BAUERMEISTER, ANELIZE; REZENDE-TEIXEIRA, PAULA; DOS SANTOS, EVELYNE ALVES; BERALDO DE MORAES, LUIZ ALBERTO; MACHADO-NETO, JOAO AGOSTINHO; COSTA-LOTUFO, LETICIA VERAS. Pradimicin-IRD exhibits antineoplastic effects by inducing DNA damage in colon cancer cells. Biochemical Pharmacology, v. 168, p. 38-47, OCT 2019. (17/17648-4, 15/17177-6, 18/17595-0, 17/24993-0, 14/50926-0)

DE VASCONCELOS, DEBORA NALIATI; LIMA, ANGELICA NAKAGAWA; PHILOT, ERIC ALLISON; SCOTT, ANA LIGIA; FERREIRA BOZA, IZABELLE AMORIM; DE SOUZA, AGUINALDO ROBINSON; MORGON, NELSON HENRIQUE; XIMENES, VALDECIR FARIAS. Methyl divanillate: redox properties and binding affinity with albumin of an antioxidant and potential NADPH oxidase inhibitor. RSC ADVANCES, v. 9, n. 35, p. 19983-19992, JUL 1 2019. (14/50926-0, 16/20549-5, 16/22014-1)

DOS SANTOS, GUSTAVO SOUZA; TEIXEIRA, THAIZ RODRIGUES; COLEPICOLO, PIO; DEBONSI, HOSANA MARIA. Natural Products from the Poles: Structural Diversity and Biological Activities. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 31, n. 5, p. 531-560, OCT 2021. (14/50926-0)

DOS SANTOS, MARIANA BASTOS; MARQUES, BEATRIZ CARVALHO; AYUSSO, GABRIELA MIRANDA; ROCHA GARCIA, MAYARA APARECIDA; PARACATU, LUANA CHIQUETTO; PAULI, IVANI; BOLZANI, VANDERLAN SILVA; ANDRICOPULO, ADRIANO DEFINI; XIMENES, VALDECIR FARIAS; ZERAIK, MARIA LUIZA; et al. Chalcones and their B-aryl analogues as myeloperoxidase inhibitors: In silico, in vitro and ex vivo investigations. BIOORGANIC CHEMISTRY, v. 110, MAY 2021. (16/00580-5, 14/18330-0, 09/53989-4, 18/15083-2, 14/50926-0)

CASTANEDA, CAROL; BRAVO, KARENT; CORTES, NATALIE; BEDOYA, JANETH; BORGES, WARLEY DE S.; BASTIDA, JAUME; OSORIO, EDISON. Amaryllidaceae alkaloids in skin cancer management: Photoprotective effect on human keratinocytes and anti-proliferative activity in melanoma cells. JOURNAL OF APPLIED BIOMEDICINE, v. 21, n. 1, p. 12-pg., 2023-03-31. (14/50926-0)

SELEGATO, DENISE M.; FREITAS, THAMIRES R.; PIVATTO, MARCOS; PIVATTO, AMANDA D.; PILON, ALAN C.; CASTRO-GAMBOA, IAN. Time-related multivariate strategy for the comprehensive evaluation of microbial chemical data. METABOLOMICS, v. 18, n. 6, p. 14-pg., 2022-05-24. (14/05935-0, 13/07600-3, 14/50926-0)

SOUZA, OTAVIO AGUIAR; RAMALHAO, VICTORIA GIOVANNA DA SILVA; TRENTIN, LUCAS DE MELO; FUNARI, CRISTIANO SOLEO; CARNEIRO, RENATO LAJARIM; BOLZANI, VANDERLAN DA SILVA; RINALDO, DANIEL. Combining natural deep eutectic solvent and microwave irradiation towards the eco-friendly and optimized extraction of bioactive phenolics from Eugenia uniflora L.. SUSTAINABLE CHEMISTRY AND PHARMACY, v. 26, p. 16-pg., 2022-05-01. (18/01786-1, 14/50926-0, 16/08179-8)

RIBEIRO, DAYANE C.; RUSSO, HELENA M.; FRAIGE, KARINA; ZERAIK, MARIA L.; NOGUEIRA, CLAUDIO R.; DA SILVA, PATRICIA B.; CODO, ANA C.; CALIXTO, GIOVANA M. F.; DE MEDEIROS, ALEXANDRA I.; CHORILLI, MARLUS; et al. Bioactive Biofllavonoids from Platonia insignis (Bacuri) Residues as Added Value Compounds. Journal of the Brazilian Chemical Society, v. 32, n. 4, p. 786-799, APR 2021. (16/16970-7, 17/18807-9, 14/50926-0, 17/19870-6, 13/07600-3)

VALLI, MARILIA; ATANAZIO, LETICIA CRISTINA VIEIRA; MONTEIRO, GUSTAVO CLARO; COELHO, ROBERTA RAMOS; DEMARQUE, DANIEL PECORARO; ANDRICOPULO, ADRIANO DEFINI; ESPINDOLA, LAILA SALMEN; BOLZANI, VANDERLAN DA SILVA. The Potential of Biologically Active Brazilian Plant Species as a Strategy to Search for Molecular Models for Mosquito Control. Planta Medica, v. 87, n. 01/02, p. 6-23, FEB 2021. (14/50926-0, 13/07600-3, 19/05967-3)

SANTOS REGINALDO, FERNANDA PRISCILA; PIRES BUENO, PAULA CAROLINA; DE MATOS COSTA, ISABELLY CRISTINA; ROQUE, ALAN DE ARAUJO; FETT-NETO, ARTHUR GERMANO; CAVALHEIRO, ALBERTO JOSE; GIORDANI, RAQUEL BRANDT. Molecular Networking Discloses the Chemical Diversity of Flavonoids and Selaginellins in Selaginella convoluta. Planta Medica, v. 87, n. 01/02, p. 113-123, FEB 2021. (14/50926-0, 19/08477-7, 17/19702-6)

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DE LIMA, DANIELE RODRIGUES; DE ARAUJO FRANCA, MARIA GLEIZIANE; EVANGELISTA DE OLIVEIRA, FATIMA DE CASSIA; PESSOA, CLAUDIA DO O.; CAVALHEIRO, ALBERTO JOSE; DE VASCONCELOS SILVA, MARIA GORETTI. METABOLIC PROFILING AND CYTOTOXIC ACTIVITY OF METHANOL EXTRACTS FROM Chamaecrista duckeana (P. BEZERRA & A. FERN.) H. S. IRWIN & BARNEBY (LEGUMINOSAE, CAESALPINIOIDEAE). Química Nova, v. N/A, p. 4-pg., 2022-04-05. (13/07600-3, 14/50926-0)

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FERREIRA, LAURA TEOFILO; MANNOCHIO-RUSSO, HELENA; ISQUIBOLA, GUILHERME; FERNANDES, RICHARD PEROSA; DE MOURAC, ANIELE; BOLZANI, VANDERLAN DA SILVA; CAIRES, FLAVIO JUNIOR. Thermal and degradation study of candesartan under pyrolysis and oxidizing conditions. JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS, v. 173, p. 9-pg., 2023-06-17. (18/24378-6, 13/07600-3, 14/50926-0)

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